Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | Phc3 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of PHC3 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | ISO | Phc3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PHC3 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Phc3 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of PHC3 mRNA | CTD | PMID:29097150 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of PHC3 mRNA | CTD | PMID:23019147 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Phc3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PHC3 mRNA | CTD | PMID:21354282 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Phc3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PHC3 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Phc3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PHC3 mRNA | CTD | PMID:24680724 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Phc3 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 4,4'-sulfonyldiphenol | decreases expression | EXP | | 6480464 | bisphenol S results in decreased expression of PHC3 mRNA | CTD | PMID:30616060 | aflatoxin B1 | increases expression | ISO | Phc3 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PHC3 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of PHC3 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | EXP | | 6480464 | aflatoxin B2 results in decreased methylation of PHC3 intron | CTD | PMID:30157460 | antirheumatic drug | decreases expression | EXP | | 6480464 | Antirheumatic Agents results in decreased expression of PHC3 mRNA | CTD | PMID:24449571 | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to PHC3 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases methylation | ISO | Phc3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of PHC3 intron | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | EXP | | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[e]pyrene | increases methylation | EXP | | 6480464 | benzo(e)pyrene results in increased methylation of PHC3 intron | CTD | PMID:30157460 | bisphenol A | decreases expression | ISO | Phc3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of PHC3 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Phc3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PHC3 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | ISO | Phc3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PHC3 mRNA | CTD | PMID:30816183 and PMID:32528016 | bortezomib | increases expression | EXP | | 6480464 | Bortezomib results in increased expression of PHC3 mRNA | CTD | PMID:20977926 | butanal | decreases expression | EXP | | 6480464 | butyraldehyde results in decreased expression of PHC3 mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PHC3 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PHC3 mRNA | CTD | PMID:35301059 | caffeine | affects phosphorylation | EXP | | 6480464 | Caffeine affects the phosphorylation of PHC3 protein | CTD | PMID:35688186 | carbon nanotube | decreases expression | ISO | Phc3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | choline | multiple interactions | ISO | Phc3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PHC3 gene | CTD | PMID:20938992 | ciguatoxin CTX1B | affects expression | ISO | Phc3 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of PHC3 mRNA | CTD | PMID:18353800 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of PHC3 mRNA | CTD | PMID:19320972 | copper(II) sulfate | increases expression | EXP | | 6480464 | Copper Sulfate results in increased expression of PHC3 mRNA | CTD | PMID:19549813 | coumarin | affects phosphorylation | EXP | | 6480464 | coumarin affects the phosphorylation of PHC3 protein | CTD | PMID:35688186 | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of PHC3 mRNA | CTD | PMID:18687144 | CU-O LINKAGE | increases expression | EXP | | 6480464 | cupric oxide results in increased expression of PHC3 mRNA | CTD | PMID:22077320 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of PHC3 mRNA | CTD | PMID:22147139 and PMID:25562108 | cylindrospermopsin | increases expression | EXP | | 6480464 | cylindrospermopsin results in increased expression of PHC3 mRNA | CTD | PMID:24921660 | dicrotophos | increases expression | EXP | | 6480464 | dicrotophos results in increased expression of PHC3 mRNA | CTD | PMID:28302478 | disodium selenite | decreases expression | EXP | | 6480464 | Sodium Selenite results in decreased expression of PHC3 mRNA | CTD | PMID:18175754 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of PHC3 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | EXP | | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PHC3 protein | CTD | PMID:23301498 | ethyl methanesulfonate | increases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in increased expression of PHC3 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | ISO | Phc3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PHC3 gene | CTD | PMID:20938992 | folic acid | decreases expression | ISO | Phc3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PHC3 mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | EXP | | 6480464 | FR900359 affects the phosphorylation of PHC3 protein | CTD | PMID:37730182 | gentamycin | increases expression | ISO | Phc3 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of PHC3 mRNA | CTD | PMID:33387578 | L-methionine | multiple interactions | ISO | Phc3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of PHC3 gene | CTD | PMID:20938992 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of PHC3 mRNA | CTD | PMID:28988120 | methapyrilene | increases methylation | EXP | | 6480464 | Methapyrilene results in increased methylation of PHC3 intron | CTD | PMID:30157460 | methyl methanesulfonate | increases expression | EXP | | 6480464 | Methyl Methanesulfonate results in increased expression of PHC3 mRNA | CTD | PMID:23649840 | N,N-diethyl-m-toluamide | multiple interactions | ISO | Phc3 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of PHC3 gene | CTD | PMID:33148267 | nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of PHC3 mRNA | CTD | PMID:24768652 and PMID:25583101 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PHC3 mRNA | CTD | PMID:22230336 | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of PHC3 mRNA | CTD | PMID:27153767 | permethrin | multiple interactions | ISO | Phc3 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of PHC3 gene | CTD | PMID:33148267 | sodium arsenate | decreases expression | ISO | Phc3 (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of PHC3 mRNA | CTD | PMID:21795629 | succimer | multiple interactions | ISO | Phc3 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of PHC3 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of PHC3 mRNA | CTD | PMID:21641980 and PMID:26378955 | temozolomide | increases expression | EXP | | 6480464 | Temozolomide results in increased expression of PHC3 mRNA | CTD | PMID:31758290 | thioacetamide | increases expression | ISO | Phc3 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of PHC3 mRNA | CTD | PMID:34492290 | torcetrapib | increases expression | EXP | | 6480464 | torcetrapib results in increased expression of PHC3 mRNA | CTD | PMID:23228038 | troglitazone | decreases expression | ISO | Phc3 (Mus musculus) | 6480464 | troglitazone results in decreased expression of PHC3 mRNA | CTD | PMID:28973697 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of PHC3 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | Phc3 (Rattus norvegicus) | 6480464 | Valproic Acid results in decreased expression of PHC3 mRNA | CTD | PMID:29427782 | valproic acid | affects splicing | ISO | Phc3 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of PHC3 mRNA | CTD | PMID:29427782 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of PHC3 mRNA | CTD | PMID:28001369 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of PHC3 mRNA | CTD | PMID:23179753 and PMID:25979313 | zinc atom | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of PHC3 mRNA | CTD | PMID:18356318 | zinc(0) | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of PHC3 mRNA | CTD | PMID:18356318 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
|
| You must be logged in to use this feature |
| {{ loginError }} |
|
|
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
|
||||||||||
Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations Click to see Annotation Detail View
