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Gene: D2hgdh (D-2-hydroxyglutarate dehydrogenase) Mus musculus
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Symbol: D2hgdh
Name: D-2-hydroxyglutarate dehydrogenase
Description: Predicted to have (R)-2-hydroxyglutarate dehydrogenase activity. Predicted to be involved in several processes, including response to cobalt ion; response to manganese ion; and response to zinc ion. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in D-2-hydroxyglutaric aciduria 1. Orthologous to human D2HGDH (D-2-hydroxyglutarate dehydrogenase); INTERACTS WITH 4-hydroxyphenyl retinamide; doxorubicin; methylphenidate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408776; AA408778; AI325464; D-2-hydroxyglutarate dehydrogenase, mitochondrial
Orthologs:
Homo sapiens (human) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
Canis lupus familiaris (dog) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : D2hgdh (D-2-hydroxyglutarate dehydrogenase)
Sus scrofa (pig) : D2HGDH (D-2-hydroxyglutarate dehydrogenase)
more info ...
Related Pseudogenes: Gm18666  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38193,823,195 - 93,853,857 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,721,817 - 95,748,751 (+)NCBIGRCm37mm9NCBIm37
MGSCv36195,655,699 - 95,682,580 (+)NCBImm8
Celera196,769,310 - 96,788,219 (+)NCBICelera
Cytogenetic Map1 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on D2hgdh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317480
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.