Phc2 (polyhomeotic 2) - Rat Genome Database

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Gene: Phc2 (polyhomeotic 2) Mus musculus
Analyze
Symbol: Phc2
Name: polyhomeotic 2
RGD ID: 1317381
MGI Page MGI
Description: Predicted to enable chromatin binding activity; histone binding activity; and identical protein binding activity. Acts upstream of or within spermatogenesis. Located in heterochromatin and nucleus. Part of PRC1 complex. Is expressed in several structures, including central nervous system and retina nuclear layer. Orthologous to human PHC2 (polyhomeotic homolog 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A3galt2; AA415044; D130050K19Rik; D4Ertd810; D4Ertd810e; early development regulator 2; early development regulator 2 (homolog of polyhomeotic 2); early development regulatory protein 2; Edr; Edr2; Mph; Mph2; p36; polyhomeotic 2 protein; polyhomeotic-like 2; polyhomeotic-like 2 (Drosophila); polyhomeotic-like protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394128,548,448 - 128,646,674 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4128,548,495 - 128,646,674 (+)EnsemblGRCm39 Ensembl
GRCm384128,654,655 - 128,752,881 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4128,654,702 - 128,752,881 (+)EnsemblGRCm38mm10GRCm38
MGSCv374128,382,240 - 128,430,118 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,207,300 - 128,255,178 (+)NCBIMGSCv36mm8
Celera4127,043,568 - 127,091,635 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
heterochromatin  (IDA)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IDA,ISO)
PcG protein complex  (ISO)
PRC1 complex  (IBA,IDA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axial skeleton morphology  (IAGP)
abnormal basioccipital bone morphology  (IAGP)
abnormal bone ossification  (IAGP)
abnormal cervical vertebrae morphology  (IAGP)
abnormal exoccipital bone morphology  (IAGP)
abnormal first pharyngeal arch morphology  (IAGP)
abnormal hyoid bone morphology  (IAGP)
abnormal occipital bone morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal second pharyngeal arch morphology  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal sternocostal joint morphology  (IAGP)
abnormal sternum morphology  (IAGP)
abnormal supraoccipital bone morphology  (IAGP)
abnormal thoracic cage morphology  (IAGP)
abnormal tympanic ring morphology  (IAGP)
absent presphenoid bone  (IAGP)
asymmetric sternocostal joints  (IAGP)
cervical vertebral fusion  (IAGP)
cervical vertebral transformation  (IAGP)
cleft secondary palate  (IAGP)
decreased fibroblast proliferation  (IAGP)
early cellular replicative senescence  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
fusion of atlas and odontoid process  (IAGP)
incomplete somite formation  (IAGP)
increased rib number  (IAGP)
lumbar vertebral transformation  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
rib fusion  (IAGP)
scapular bone foramen  (IAGP)
small tail bud  (IAGP)
split cervical atlas  (IAGP)
split cervical axis  (IAGP)
thoracic vertebral transformation  (IAGP)
vertebral transformation  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. PRC1 complex diversity: where is it taking us? Gil J and O'Loghlen A, Trends Cell Biol. 2014 Jul 22. pii: S0962-8924(14)00102-0. doi: 10.1016/j.tcb.2014.06.005.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
Additional References at PubMed
PMID:8889548   PMID:9627119   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11950896   PMID:12034499   PMID:12183370   PMID:12384788   PMID:12477932  
PMID:14610273   PMID:15009096   PMID:15033168   PMID:15226823   PMID:15489334   PMID:15580621   PMID:15735665   PMID:15741318   PMID:15782199   PMID:16024804   PMID:16141072   PMID:16141073  
PMID:16359901   PMID:16815646   PMID:17215307   PMID:17296600   PMID:17967808   PMID:18311137   PMID:18799693   PMID:19369945   PMID:19515240   PMID:20471950   PMID:21059868   PMID:21267068  
PMID:21677750   PMID:21873635   PMID:22325148   PMID:22496869   PMID:22872859   PMID:22922362   PMID:23605804   PMID:24091011   PMID:26206133   PMID:28900001   PMID:30186101   PMID:31375680  
PMID:32325033   PMID:33603070   PMID:34321999  


Genomics

Comparative Map Data
Phc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394128,548,448 - 128,646,674 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4128,548,495 - 128,646,674 (+)EnsemblGRCm39 Ensembl
GRCm384128,654,655 - 128,752,881 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4128,654,702 - 128,752,881 (+)EnsemblGRCm38mm10GRCm38
MGSCv374128,382,240 - 128,430,118 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,207,300 - 128,255,178 (+)NCBIMGSCv36mm8
Celera4127,043,568 - 127,091,635 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.12NCBI
PHC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38133,323,626 - 33,431,095 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl133,323,623 - 33,431,095 (-)EnsemblGRCh38hg38GRCh38
GRCh37133,789,227 - 33,896,696 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,561,811 - 33,613,781 (-)NCBINCBI36Build 36hg18NCBI36
Build 34133,458,319 - 33,510,287NCBI
Celera132,060,914 - 32,112,987 (-)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef131,905,459 - 31,957,330 (-)NCBIHuRef
CHM1_1133,904,604 - 33,956,563 (-)NCBICHM1_1
T2T-CHM13v2.0133,185,234 - 33,292,697 (-)NCBIT2T-CHM13v2.0
Phc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85146,285,000 - 146,383,664 (+)NCBIGRCr8
mRatBN7.25141,000,604 - 141,099,268 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5141,050,842 - 141,099,268 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5143,746,693 - 143,795,043 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05145,516,522 - 145,564,872 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05145,517,431 - 145,565,795 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05146,832,552 - 146,931,444 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5146,882,756 - 146,931,444 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05150,570,311 - 150,668,954 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45147,930,703 - 147,978,856 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15147,924,729 - 147,988,894 (+)NCBI
Celera5139,535,101 - 139,583,492 (+)NCBICelera
Cytogenetic Map5q36NCBI
Phc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545211,491,573 - 11,538,618 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545211,490,336 - 11,538,618 (-)NCBIChiLan1.0ChiLan1.0
PHC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21193,395,679 - 193,503,266 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11192,517,821 - 192,625,405 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0132,609,560 - 32,717,143 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1133,794,951 - 33,901,741 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl133,794,950 - 33,846,913 (-)Ensemblpanpan1.1panPan2
PHC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,993,587 - 68,115,307 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl267,993,366 - 68,115,324 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha264,571,172 - 64,693,473 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0268,554,343 - 68,677,404 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,554,359 - 68,677,400 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1265,366,474 - 65,490,177 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,389,728 - 66,512,720 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,381,540 - 67,504,721 (+)NCBIUU_Cfam_GSD_1.0
Phc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505850,322,918 - 50,427,312 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647416,145,496 - 16,236,854 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647416,147,699 - 16,252,073 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl689,574,035 - 89,685,272 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1689,574,030 - 89,685,275 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2683,623,713 - 83,647,255 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12099,447,099 - 99,558,783 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2099,507,489 - 99,557,540 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603317,134,794 - 17,246,546 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476416,351,954 - 16,456,119 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476416,353,193 - 16,456,115 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Phc2
137 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3969
Count of miRNA genes:739
Interacting mature miRNAs:953
Transcripts:ENSMUST00000030588, ENSMUST00000106079, ENSMUST00000106080, ENSMUST00000120946, ENSMUST00000133439, ENSMUST00000134421, ENSMUST00000136377, ENSMUST00000138445, ENSMUST00000143632, ENSMUST00000147572, ENSMUST00000148723, ENSMUST00000155653
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
10412072Ssen1_msuseptibility to Sendai virus 1 (mouse)Not determined4109658132133154782Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1300655Nidds_mnon-insulin-dependent diabetes mellitus in SJL (mouse)Not determined4115030777129465915Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494732255128732454Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse

Markers in Region
RH124377  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384128,752,646 - 128,752,747UniSTSGRCm38
MGSCv374128,429,890 - 128,429,991UniSTSGRCm37
Celera4127,091,407 - 127,091,508UniSTS
Cytogenetic Map4D2.2UniSTS
UniSTS:235033  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384128,740,371 - 128,740,592UniSTSGRCm38
MGSCv374128,417,615 - 128,417,836UniSTSGRCm37
Celera4127,079,137 - 127,079,358UniSTS
Cytogenetic Map4D2.2UniSTS
UniSTS:235034  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384128,752,592 - 128,752,794UniSTSGRCm38
MGSCv374128,429,836 - 128,430,038UniSTSGRCm37
Celera4127,091,353 - 127,091,555UniSTS
Cytogenetic Map4D2.2UniSTS
Edr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384128,744,852 - 128,745,872UniSTSGRCm38
MGSCv374128,422,096 - 128,423,116UniSTSGRCm37
Celera4127,083,614 - 127,084,634UniSTS
Cytogenetic Map4D2.2UniSTS
cM Map461.0UniSTS
D4Ertd810e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384128,752,634 - 128,752,850UniSTSGRCm38
MGSCv374128,429,878 - 128,430,094UniSTSGRCm37
Celera4127,091,395 - 127,091,611UniSTS
Cytogenetic Map4D2.2UniSTS
cM Map461.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001195083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001195130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_018774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017320320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004941936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_376334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB062362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF060076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL611969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL611983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC071246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE995150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU210837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU467499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U81491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000030588   ⟹   ENSMUSP00000030588
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,548,495 - 128,646,674 (+)Ensembl
GRCm38.p6 Ensembl4128,654,702 - 128,752,881 (+)Ensembl
Ensembl Acc Id: ENSMUST00000106079   ⟹   ENSMUSP00000101689
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,621,378 - 128,646,674 (+)Ensembl
GRCm38.p6 Ensembl4128,727,585 - 128,752,881 (+)Ensembl
Ensembl Acc Id: ENSMUST00000106080   ⟹   ENSMUSP00000101690
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,582,588 - 128,646,674 (+)Ensembl
GRCm38.p6 Ensembl4128,688,795 - 128,752,881 (+)Ensembl
Ensembl Acc Id: ENSMUST00000120946   ⟹   ENSMUSP00000113875
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,621,764 - 128,637,264 (+)Ensembl
GRCm38.p6 Ensembl4128,727,971 - 128,743,471 (+)Ensembl
Ensembl Acc Id: ENSMUST00000133439   ⟹   ENSMUSP00000117163
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,621,503 - 128,638,801 (+)Ensembl
GRCm38.p6 Ensembl4128,727,710 - 128,745,008 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134421   ⟹   ENSMUSP00000123307
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,621,775 - 128,640,925 (+)Ensembl
GRCm38.p6 Ensembl4128,727,982 - 128,747,132 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136377   ⟹   ENSMUSP00000116333
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,548,531 - 128,605,987 (+)Ensembl
GRCm38.p6 Ensembl4128,654,738 - 128,712,194 (+)Ensembl
Ensembl Acc Id: ENSMUST00000138445   ⟹   ENSMUSP00000117688
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,621,475 - 128,642,010 (+)Ensembl
GRCm38.p6 Ensembl4128,727,682 - 128,748,217 (+)Ensembl
Ensembl Acc Id: ENSMUST00000143632   ⟹   ENSMUSP00000120468
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,621,374 - 128,646,674 (+)Ensembl
GRCm38.p6 Ensembl4128,727,581 - 128,752,881 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147572   ⟹   ENSMUSP00000118298
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,621,726 - 128,641,867 (+)Ensembl
GRCm38.p6 Ensembl4128,727,933 - 128,748,074 (+)Ensembl
Ensembl Acc Id: ENSMUST00000148723
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,582,531 - 128,599,456 (+)Ensembl
GRCm38.p6 Ensembl4128,688,738 - 128,705,663 (+)Ensembl
Ensembl Acc Id: ENSMUST00000155653
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4128,603,957 - 128,618,217 (+)Ensembl
GRCm38.p6 Ensembl4128,710,164 - 128,724,424 (+)Ensembl
RefSeq Acc Id: NM_001195083   ⟹   NP_001182012
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,621,364 - 128,646,674 (+)NCBI
GRCm384128,727,571 - 128,752,881 (+)NCBI
Celera4126,993,212 - 127,091,642 (+)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001195130   ⟹   NP_001182059
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,548,495 - 128,646,674 (+)NCBI
GRCm384128,654,702 - 128,752,881 (+)NCBI
Celera4126,993,212 - 127,091,642 (+)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_018774   ⟹   NP_061244
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,582,531 - 128,646,674 (+)NCBI
GRCm384128,688,738 - 128,752,881 (+)NCBI
MGSCv374128,382,240 - 128,430,118 (+)RGD
Celera4126,993,212 - 127,091,642 (+)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006503234   ⟹   XP_006503297
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,548,492 - 128,646,668 (+)NCBI
GRCm384128,654,697 - 128,752,875 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006503236   ⟹   XP_006503299
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,621,731 - 128,646,668 (+)NCBI
GRCm384128,727,938 - 128,752,875 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006503238   ⟹   XP_006503301
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,621,780 - 128,646,668 (+)NCBI
GRCm384128,727,987 - 128,752,875 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011240576   ⟹   XP_011238878
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,548,448 - 128,635,851 (+)NCBI
GRCm384128,654,655 - 128,742,066 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017320320   ⟹   XP_017175809
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,548,648 - 128,646,668 (+)NCBI
GRCm384128,654,855 - 128,752,875 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036164241   ⟹   XP_036020134
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,621,367 - 128,646,667 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004941936
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,548,448 - 128,641,988 (+)NCBI
Sequence:
RefSeq Acc Id: XR_376334
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394128,548,448 - 128,646,667 (+)NCBI
GRCm384128,654,655 - 128,752,874 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001182012 (Get FASTA)   NCBI Sequence Viewer  
  NP_001182059 (Get FASTA)   NCBI Sequence Viewer  
  NP_061244 (Get FASTA)   NCBI Sequence Viewer  
  XP_006503297 (Get FASTA)   NCBI Sequence Viewer  
  XP_006503299 (Get FASTA)   NCBI Sequence Viewer  
  XP_006503301 (Get FASTA)   NCBI Sequence Viewer  
  XP_011238878 (Get FASTA)   NCBI Sequence Viewer  
  XP_017175809 (Get FASTA)   NCBI Sequence Viewer  
  XP_036020134 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC23570 (Get FASTA)   NCBI Sequence Viewer  
  AAD00519 (Get FASTA)   NCBI Sequence Viewer  
  AAH57571 (Get FASTA)   NCBI Sequence Viewer  
  AAH71246 (Get FASTA)   NCBI Sequence Viewer  
  BAB93527 (Get FASTA)   NCBI Sequence Viewer  
  CAQ52290 (Get FASTA)   NCBI Sequence Viewer  
  CAQ52291 (Get FASTA)   NCBI Sequence Viewer  
  CAQ52292 (Get FASTA)   NCBI Sequence Viewer  
  CAQ52293 (Get FASTA)   NCBI Sequence Viewer  
  CAQ52299 (Get FASTA)   NCBI Sequence Viewer  
  EDL30229 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000030588
  ENSMUSP00000030588.7
  ENSMUSP00000101689
  ENSMUSP00000101689.4
  ENSMUSP00000101690
  ENSMUSP00000101690.2
  ENSMUSP00000113875.2
  ENSMUSP00000116333.2
  ENSMUSP00000117163.2
  ENSMUSP00000117688.2
  ENSMUSP00000118298.2
  ENSMUSP00000120468.2
  ENSMUSP00000123307.2
GenBank Protein Q9QWH1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_061244   ⟸   NM_018774
- Peptide Label: isoform A
- UniProtKB: O88463 (UniProtKB/Swiss-Prot),   B1ASA4 (UniProtKB/Swiss-Prot),   B1AS98 (UniProtKB/Swiss-Prot),   Q8K5D9 (UniProtKB/Swiss-Prot),   Q9QWH1 (UniProtKB/Swiss-Prot),   B2KFW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001182059   ⟸   NM_001195130
- Peptide Label: isoform A
- UniProtKB: O88463 (UniProtKB/Swiss-Prot),   B1ASA4 (UniProtKB/Swiss-Prot),   B1AS98 (UniProtKB/Swiss-Prot),   Q8K5D9 (UniProtKB/Swiss-Prot),   Q9QWH1 (UniProtKB/Swiss-Prot),   B2KFW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001182012   ⟸   NM_001195083
- Peptide Label: isoform B
- UniProtKB: Q9QWH1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006503297   ⟸   XM_006503234
- Peptide Label: isoform X2
- UniProtKB: B2KFW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006503299   ⟸   XM_006503236
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006503301   ⟸   XM_006503238
- Peptide Label: isoform X5
- UniProtKB: Q9QWH1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011238878   ⟸   XM_011240576
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017175809   ⟸   XM_017320320
- Peptide Label: isoform X1
- UniProtKB: O88463 (UniProtKB/Swiss-Prot),   B1ASA4 (UniProtKB/Swiss-Prot),   B1AS98 (UniProtKB/Swiss-Prot),   Q8K5D9 (UniProtKB/Swiss-Prot),   Q9QWH1 (UniProtKB/Swiss-Prot),   B2KFW6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000117688   ⟸   ENSMUST00000138445
Ensembl Acc Id: ENSMUSP00000120468   ⟸   ENSMUST00000143632
Ensembl Acc Id: ENSMUSP00000117163   ⟸   ENSMUST00000133439
Ensembl Acc Id: ENSMUSP00000118298   ⟸   ENSMUST00000147572
Ensembl Acc Id: ENSMUSP00000101689   ⟸   ENSMUST00000106079
Ensembl Acc Id: ENSMUSP00000101690   ⟸   ENSMUST00000106080
Ensembl Acc Id: ENSMUSP00000113875   ⟸   ENSMUST00000120946
Ensembl Acc Id: ENSMUSP00000123307   ⟸   ENSMUST00000134421
Ensembl Acc Id: ENSMUSP00000030588   ⟸   ENSMUST00000030588
Ensembl Acc Id: ENSMUSP00000116333   ⟸   ENSMUST00000136377
RefSeq Acc Id: XP_036020134   ⟸   XM_036164241
- Peptide Label: isoform X5
Protein Domains
FCS-type   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QWH1-F1-model_v2 AlphaFold Q9QWH1 1-850 view protein structure

Promoters
RGD ID:6835843
Promoter ID:MM_KWN:39738
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000021842
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364128,387,221 - 128,388,022 (+)MPROMDB
RGD ID:6847830
Promoter ID:MM_ACW:35766
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung,   Spleen
Transcripts:PHC2.FSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364128,388,666 - 128,389,166 (+)MPROMDB
RGD ID:6835845
Promoter ID:MM_KWN:39739
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000106078,   ENSMUST00000120946,   OTTMUST00000021841,   OTTMUST00000021843,   OTTMUST00000021844,   OTTMUST00000021845,   OTTMUST00000021846,   UC008UVK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364128,403,941 - 128,405,432 (+)MPROMDB
RGD ID:6884716
Promoter ID:EPDNEW_M5809
Type:initiation region
Name:Phc2_2
Description:Mus musculus polyhomeotic 2 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5810  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384128,654,698 - 128,654,758EPDNEW
RGD ID:6884718
Promoter ID:EPDNEW_M5810
Type:initiation region
Name:Phc2_1
Description:Mus musculus polyhomeotic 2 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5809  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384128,727,611 - 128,727,671EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1860454 AgrOrtholog
Ensembl Genes ENSMUSG00000028796 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030588 ENTREZGENE
  ENSMUST00000030588.13 UniProtKB/Swiss-Prot
  ENSMUST00000106079 ENTREZGENE
  ENSMUST00000106079.10 UniProtKB/Swiss-Prot
  ENSMUST00000106080 ENTREZGENE
  ENSMUST00000106080.8 UniProtKB/Swiss-Prot
  ENSMUST00000120946.2 UniProtKB/TrEMBL
  ENSMUST00000133439.8 UniProtKB/TrEMBL
  ENSMUST00000134421.2 UniProtKB/TrEMBL
  ENSMUST00000136377.8 UniProtKB/TrEMBL
  ENSMUST00000138445.2 UniProtKB/TrEMBL
  ENSMUST00000143632.8 UniProtKB/TrEMBL
  ENSMUST00000147572.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.60.160 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PcG_chromatin_remod_factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FCS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FCS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:54383 UniProtKB/Swiss-Prot
MGD MGI:1860454 ENTREZGENE
NCBI Gene 54383 ENTREZGENE
PANTHER POLYCOMB GROUP PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POLYHOMEOTIC-LIKE PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PHC2_SAM_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-FCS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Phc2 PhenoGen
PROSITE SAM_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_FCS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B1AS97_MOUSE UniProtKB/TrEMBL
  B1AS98 ENTREZGENE
  B1ASA0_MOUSE UniProtKB/TrEMBL
  B1ASA1_MOUSE UniProtKB/TrEMBL
  B1ASA2_MOUSE UniProtKB/TrEMBL
  B1ASA3_MOUSE UniProtKB/TrEMBL
  B1ASA4 ENTREZGENE
  B2KFW6 ENTREZGENE, UniProtKB/TrEMBL
  B2KGX1_MOUSE UniProtKB/TrEMBL
  B2KGX4_MOUSE UniProtKB/TrEMBL
  D6REH8_MOUSE UniProtKB/TrEMBL
  O88463 ENTREZGENE
  PHC2_MOUSE UniProtKB/Swiss-Prot
  Q8K5D9 ENTREZGENE
  Q9QWH1 ENTREZGENE
UniProt Secondary B1AS98 UniProtKB/Swiss-Prot
  B1ASA4 UniProtKB/Swiss-Prot
  O88463 UniProtKB/Swiss-Prot
  Q8K5D9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-31 Phc2  polyhomeotic 2    polyhomeotic-like 2 (Drosophila)  Symbol and/or name change 5135510 APPROVED