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Gene: LACTB2 (lactamase beta 2) Homo sapiens
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Symbol: LACTB2
Name: lactamase beta 2
Description: Exhibits endoribonuclease activity; single-stranded RNA binding activity; and zinc ion binding activity. Involved in RNA phosphodiester bond hydrolysis, endonucleolytic. Localizes to the mitochondrial matrix; INTERACTS WITH (+)-catechin; (-)-demecolcine; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta-lactamase-like protein 2; CGI-83; endoribonuclease LACTB2; lactamase, beta 2; testicular secretory protein Li 23
Orthologs:
Mus musculus (house mouse) : Lactb2 (lactamase, beta 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lactb2 (lactamase, beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lactb2 (lactamase beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LACTB2 (lactamase beta 2)
Canis lupus familiaris (dog) : LACTB2 (lactamase beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lactb2 (lactamase beta 2)
Sus scrofa (pig) : LACTB2 (lactamase beta 2)
Chlorocebus sabaeus (green monkey) : LACTB2 (lactamase beta 2)
Heterocephalus glaber (naked mole-rat) : Lactb2 (lactamase beta 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl870,635,318 - 70,669,185 (-)Ensembl
GRCh38870,637,266 - 70,669,185 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37871,549,501 - 71,581,447 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36871,712,045 - 71,743,946 (-)NCBINCBI36hg18NCBI36
Build 34871,712,044 - 71,743,946NCBI
Celera867,547,128 - 67,579,082 (-)NCBI
Cytogenetic Map8q13.3ENTREZGENE
HuRef867,042,341 - 67,074,194 (-)NCBIHuRef
CHM1_1871,605,012 - 71,636,965 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LACTB2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317324
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.