Sat2 (spermidine/spermine N1-acetyl transferase 2)

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Gene: Sat2 (spermidine/spermine N1-acetyl transferase 2) Mus musculus

Analyze

Symbol:

Sat2

Name:

spermidine/spermine N1-acetyl transferase 2

RGD ID:

1317313

MGI Page

MGI

Description:

Predicted to have diamine N-acetyltransferase activity; identical protein binding activity; and spermidine binding activity. Predicted to be involved in polyamine metabolic process. Predicted to localize to cytoplasm. Orthologous to human SAT2 (spermidine/spermine N1-acetyltransferase family member 2); PARTICIPATES IN hypoxia inducible factor pathway; arginine and proline metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; busulfan; cerium trichloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

2610016A03Rik; diamine acetyltransferase 2; MGC74376; polyamine N-acetyltransferase 2; spermidine/spermine N(1)-acetyltransferase 2; SS; SSA; SSAT-2; SSAT2; thialysine N-epsilon-acetyltransferase

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	69,512,824 - 69,514,857 (+)	NCBI	GRCm39		mm39
GRCm38	11	69,621,996 - 69,624,032 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	69,622,024 - 69,623,870 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	69,435,611 - 69,437,371 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	69,438,219 - 69,440,480 (+)	NCBI			mm8
MGSCv36	11	70,206,131 - 70,208,392 (+)	NCBI			mm8
Cytogenetic Map	11	B3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

dyskeratosis congenita (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1-naphthyl isothiocyanate (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (ISO)

2,6-dinitrotoluene (ISO)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

acetamide (ISO)

antirheumatic drug (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

bisphenol F (ISO)

buspirone (ISO)

busulfan (EXP)

carbamazepine (ISO)

cerium trichloride (EXP)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

diclofenac (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (ISO)

ethyl methanesulfonate (ISO)

flutamide (ISO)

formaldehyde (ISO)

glafenine (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

lead(0) (ISO)

lead(2+) (ISO)

leflunomide (ISO)

methyl methanesulfonate (ISO)

paracetamol (EXP)

phenobarbital (ISO)

pirinixic acid (EXP,ISO)

potassium chromate (ISO)

pravastatin (EXP,ISO)

rac-lactic acid (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sulindac (EXP)

tetrachloromethane (EXP,ISO)

thioacetamide (ISO)

trichloroethene (ISO)

trichostatin A (ISO)

trimellitic anhydride (EXP)

valproic acid (ISO)

zaragozic acid A (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

nor-spermidine metabolic process (ISO)

polyamine biosynthetic process (ISO)

putrescine acetylation (ISO)

spermidine acetylation (IBA,ISO)

spermidine metabolic process (ISA)

spermine acetylation (ISO)

spermine metabolic process (ISA)

Cellular Component

cytoplasm (IEA)

Molecular Function

diamine N-acetyltransferase activity (IBA,ISA,ISO)

identical protein binding (ISO)

N-acetyltransferase activity (IBA,ISO)

protein binding (ISO)

spermidine binding (IBA)

transferase activity (IEA)

transferase activity, transferring acyl groups (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

arginine and proline metabolic pathway (IEA)

hypoxia inducible factor pathway (ISO)

References

References - curated


1.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGD data from the GO Consortium
3.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	Pipeline to import KEGG annotations from KEGG into RGD
5.	RGD automated import pipeline for gene-chemical interactions
6.	Semenza GL Physiology (Bethesda). 2009 Apr;24:97-106.

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11752298	PMID:12477932	PMID:12803540	PMID:14610273	PMID:14681479	PMID:15489334	PMID:16141072	PMID:16141073
PMID:17371273	PMID:19164485	PMID:21267068	PMID:21677750	PMID:21873635	PMID:28578006	PMID:31253191	PMID:32325033

Genomics

Comparative Map Data

Sat2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	69,512,824 - 69,514,857 (+)	NCBI	GRCm39		mm39
GRCm38	11	69,621,996 - 69,624,032 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	69,622,024 - 69,623,870 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	69,435,611 - 69,437,371 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	11	69,438,219 - 69,440,480 (+)	NCBI			mm8
MGSCv36	11	70,206,131 - 70,208,392 (+)	NCBI			mm8
Cytogenetic Map	11	B3	NCBI

SAT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	17	7,626,234 - 7,627,876 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	17	7,626,234 - 7,627,878 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	17	7,529,552 - 7,531,194 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	7,470,281 - 7,471,889 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	17	7,470,280 - 7,471,889	NCBI
Celera	17	7,555,972 - 7,557,610 (-)	NCBI
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	7,423,586 - 7,425,224 (-)	NCBI		HuRef
CHM1_1	17	7,538,732 - 7,540,374 (-)	NCBI		CHM1_1

Sat2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	54,340,756 - 54,343,507 (+)	NCBI
Rnor_6.0 Ensembl	10	56,227,692 - 56,229,850 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	10	56,227,703 - 56,229,796 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	10	55,973,151 - 55,975,434 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	56,440,651 - 56,442,403 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	10	56,454,206 - 56,456,015 (+)	NCBI
Celera	10	53,495,543 - 53,497,295 (+)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Sat2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	9,305,746 - 9,308,668 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	9,306,210 - 9,308,668 (+)	NCBI	ChiLan1.0	ChiLan1.0

SAT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	17	7,643,490 - 7,645,127 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	7,643,490 - 7,645,127 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	17	7,657,166 - 7,658,773 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

SAT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	5	32,534,310 - 32,535,846 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	5	32,534,302 - 32,536,022 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Sat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936595	891,380 - 892,937 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SAT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	52,911,723 - 52,913,363 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	52,911,725 - 52,913,314 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	55,261,007 - 55,262,600 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SAT2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	7,001,087 - 7,003,538 (-)	NCBI
ChlSab1.1 Ensembl	16	7,001,259 - 7,002,270 (-)	Ensembl

Sat2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624786	10,232,078 - 10,233,602 (-)	NCBI

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
26884453	Sklq16_m	skull length QTL 16, 16 week (mouse)					11	3300000	72800000	Mouse
13208559	Wght10_m	weight 10 (mouse)					11	4000000	89000000	Mouse
13208558	Lgth12_m	body length 12 (mouse)					11	4000000	95000000	Mouse
1300905	Scc6_m	colon tumor susceptibility 6 (mouse)			Not determined		11	6930277	89128908	Mouse
1559002	Lmrq4_m	Leishmania major resistance QTL 4 (mouse)			Not determined		11	12318637	69794121	Mouse
1357859	Lvrq7_m	liver weight QTL 7 (mouse)			Not determined		11	12318637	118131898	Mouse
39128214	Lwq20_m	liver weight QTL 20 (mouse)					11	12318637	118131898	Mouse
4141894	Nidd6k_m	Nidd6 on KK-A (mouse)			Not determined			19174204	97007000	Mouse
10412246	Dfs2_m	dental fluorosis suseptibility 2 (mouse)			Not determined		11	21857364	95990405	Mouse
1357782	Char8_m	P. chabaudi malaria resistance QTL 8 (mouse)			Not determined		11	35687789	69794161	Mouse
13208569	Bmiq10_m	body mass index QTL 10 (mouse)					11	36000000	85000000	Mouse
1301328	Mol4_m	modifier of LPS-response 4 (mouse)			Not determined		11	36391750	83590530	Mouse
1301788	Lbw8_m	lupus NZB x NZW 8 (mouse)			Not determined		11	36612460	70618665	Mouse
1301896	Tria1_m	T-cell receptor induced activation 1 (mouse)			Not determined		11	36722738	70723028	Mouse
4141853	Skmw17_m	skeletal muscle weight 17 (mouse)			Not determined		11	37190115	71190238	Mouse
10766457	Nwa3_m	New Zealand White autoimmunity 3 (mouse)					11	38125289	72125383	Mouse
11532698	Sluc36a_m	susceptibility to lung cancer 36a (mouse)					11	42365791	76365904	Mouse
11532699	Sluc36b_m	susceptibility to lung cancer 36b (mouse)					11	42365791	76365904	Mouse
4142300	Ctrq3_m	C. trachomatis resistance QTL 3 (mouse)			Not determined		11	44739211	76963931	Mouse
4141367	Inf1_m	acute ozone induced inflammation (mouse)			Not determined			44739211	113167183	Mouse
4141000	Nidd3_m	non-insulin-dependent diabetes mellitus 3 (mouse)			Not determined			45151201	79151308	Mouse
1302021	Nidd1n_m	non-insulin-dependent diabetes mellitus 1 in NSY (mouse)			Not determined		11	45275046	80087498	Mouse
1357878	Mastr_m	modifier of astrocytoma (mouse)			Not determined		11	45817754	89927907	Mouse
1300765	Bbaa4_m	B.burgdorferi-associated arthritis 4 (mouse)			Not determined		11	46294341	80294436	Mouse
1301988	Bmd11_m	bone mineral density 11 (mouse)			Not determined		11	46428581	80428696	Mouse
1301830	Ssta4_m	susceptibility to Salmonella typhimurium antigens 4 (mouse)			Not determined		11	50187365	84187585	Mouse
13524840	Ppiq9a_m	prepulse inhibition QTL 9a (mouse)					11	52603559	86603559	Mouse
1300774	Pgia7_m	proteoglycan induced arthritis 7 (mouse)			Not determined		11	53499762	87499911	Mouse
4141830	Pregq1_m	pregnancy QTL 1 (mouse)			Not determined		11	54235926	83842826	Mouse
4141875	Etax9_m	ethanol induced ataxia 9 (mouse)			Not determined			55394159	72319101	Mouse
4142121	Tmc1m2_m	Tmc1 modifier 2 (mouse)			Not determined		11	56973201	114267131	Mouse
1300664	Etohcta9_m	ethanol conditioned taste aversion 9 (mouse)			Not determined		11	57863834	91863932	Mouse
10053682	Eae45_m	experimental allergic encephalomyelitis susceptibility 45 (mouse)			Not determined		11	58599729	74863932	Mouse
1300924	Ity2_m	immunity to S. typhimurium 2 (mouse)			Not determined		1	58617204	87804412	Mouse
4141982	Skts-fp2_m	skin tumor susceptibility in FVB and PWK 2 (mouse)			Not determined			58828440	85175703	Mouse
1301987	Pid3_m	prior incubation determinant 3 (mouse)			Not determined		11	61795994	88808902	Mouse
1301319	Dautb4_m	dopamine uptake transporter binding 4 (mouse)			Not determined		11	62265179	96265327	Mouse
27226730	Tibmd1_m	tibia midshaft diameter 1, 5 week (mouse)					11	62700000	109500000	Mouse
1301999	Lmr15_m	leishmaniasis resistance 15 (mouse)			Not determined		11	63428581	81939647	Mouse
10044004	Stzid3_m	streptozotocin induced diabetes susceptibility 3 (mouse)			Not determined		11	63428581	94173092	Mouse
11039501	Ltpr6a_m	Leishmania tropica response 6a (mouse)					11	64939510	98939647	Mouse
11039502	Ltpr6b_m	Leishmania tropica response 6b (mouse)					11	64939510	98939647	Mouse
11039515	Ltpr6_m	Leishmania tropica response 6 (mouse)					11	64939510	98939647	Mouse
1301546	Pcir2_m	periosteal circumference 2 (mouse)			Not determined		11	66842594	100842826	Mouse
1357766	Si5lq6_m	serum IGFBP-5 level QTL 6 (mouse)			Not determined		11	66842594	100842826	Mouse
4141012	Femwf6_m	femur work to failure 6 (mouse)			Not determined			66842594	100842826	Mouse
1301833	Tbbmd5_m	total body bone mineral density 5 (mouse)			Not determined		11	66842594	100842826	Mouse
1300784	Prdt3_m	prion disease incubation time 3 (mouse)			Not determined		11	66842594	100842826	Mouse
1300628	Lgth6_m	body length 6 (mouse)			Not determined		11	66842594	100842826	Mouse
4142316	Ity2b_m	immunity to S. typhimurium 2b (mouse)			Not determined		11	67187365	79923086	Mouse
27226783	Tibl5_m	tibia length 5, 5 week (mouse)					11	68300000	102000000	Mouse
36049778	Ars6_m	antibody response to SARS-CoV 6, day 15, IgM (mouse)					11	69100000	72600000	Mouse
36049779	Ars7_m	antibody response to SARS-CoV 7, day 29, IgG1 (mouse)					11	69100000	72600000	Mouse
36049784	Ars8_m	antibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)					11	69100000	72600000	Mouse
36049785	Ars9_m	antibody response to SARS-CoV 9, day 29, IgM (mouse)					11	69100000	72600000	Mouse
36049786	Ars10_m	antibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)					11	69100000	72600000	Mouse
36049787	Ars11_m	antibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)					11	69100000	72600000	Mouse
36049788	Ars1_m	antibody response to SARS-CoV 1, day 7, IgG1 (mouse)					11	69100000	72600000	Mouse
36049789	Ars2_m	antibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)					11	69100000	72600000	Mouse
36049790	Ars3_m	antibody response to SARS-CoV 3, day 7, IgG2b (mouse)					11	69100000	72600000	Mouse
36049791	Ars4_m	antibody response to SARS-CoV 4, day 7, IgG3 (mouse)					11	69100000	72600000	Mouse
36049792	Ars5_m	antibody response to SARS-CoV 5, day 7, IgM (mouse)					11	69100000	72600000	Mouse
35673314	Ari2_m	antibody response to influenza 2, day 10, IgG3 (mouse)					11	69100000	72600000	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	452
Count of miRNA genes:	241
Interacting mature miRNAs:	262
Transcripts:	ENSMUST00000092969, ENSMUST00000108656, ENSMUST00000151255
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001356468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001356469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_026991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006534110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006534111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AI413743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK011406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK161230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL603707	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL731687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AV097768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BE995938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DV064807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000092969 ⟹ ENSMUSP00000090647

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	11	69,622,052 - 69,623,870 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000108656 ⟹ ENSMUSP00000104296

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	11	69,622,024 - 69,623,870 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000151255

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	11	69,622,052 - 69,623,458 (+)	Ensembl

RefSeq Acc Id:

NM_001356468 ⟹ NP_001343397

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	69,512,878 - 69,514,704 (+)	NCBI
GRCm38	11	69,622,052 - 69,623,878 (+)	NCBI

Sequence:

show sequence

AGAATTTAAGGCCTTTTCTGGCAGAAGAGACCACCAGGCCGGCTAATCCTCCCAGCTGAGACCG
TGAGGCTCGGAATGGCTTCCACGCGAATCCGAGAGGCCAGGGAGAGCGATTGTGGAGACATTAT
GAGGATGATCCGGGAACTGGCAGAGTTCGAGAAACTGTCCCATCAGGTGAAGATCAGTGAAGAA
GCTCTGCGAGCAGATGGCTTTGGAGAGAACCCTTTCTTTCACTGTTTGGTGGCAGAGATTATCC
CAGCACCTGGGGAGTCACAAGGGTCCCTTGTGGTGGGCTATGGGCTGTACTACTTCATCTATAG
CACATGGACCGGACGAAACGTTTATCTGGAAGACATCTATGTGATGCCGCAATATCGGGGTCAA
GGGATTGGTACCAAAATAATCAAAAAGGTGGCTGAGGTTGCCCTGAATAAGGGTTGCTCCCAGT
TCCGCCTGGCAGTTCTGGATTGGAACAAGAAGGCCGTGAACTTGTACAAATTTCTAGGGGCTCA
AGATCTGACTGAATCGGAAGGCTGGCTCTCCTTTCGATTTGAAGGCGAGGCAATGAGGGAGTTG
GCAGGACGCTGACTTACGCCCTCTCTCTCCTGCCTCTTCTTTGGGATCACCATATCAAGTTTTC
CTAAGACCATAACCATAGGCACTGACCCAGACAGACGCTCGCTCACCCAGAGGCCTCCCAGGGT
GCAGACTCCTGAAGTACAGAAAGAGTGGAAGAGGGAGAAGCCTTATTAGGAACCACAAATAAAA
TACTTGCTTTGCCCTCATGGGTAGAGGATGTGATGCTGCAAAAA

hide sequence

RefSeq Acc Id:

NM_001356469 ⟹ NP_001343398

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	69,512,878 - 69,514,277 (+)	NCBI
GRCm38	11	69,622,052 - 69,623,451 (+)	NCBI

Sequence:

show sequence

AGAATTTAAGGCCTTTTCTGGCAGAAGAGACCACCAGGCCGGCTAATCCTCCCAGCTGAGACCG
GTTGGTGCCAGAATCTTGTCTAGAAGCTTCTAGCATTTCTTCTGCCCCTCGCTCCCAGCACTTT
GAGACCTGAGCTTTGAGACCAGACCTCCGCGGTTCTGCAAACGTGGGAGTTGTCTGTGATCTTT
GATTTTTGACAGTGAGGCTCGGAATGGCTTCCACGCGAATCCGAGAGGCCAGGGAGAGCGATTG
TGGAGACATTATGAGGATGATCCGGGAACTGGCAGAGTTCGAGAAACTGTCCCATCAGGTGAAG
ATCAGTGAAGAAGCTCTGCGAGCAGATGGCTTTGGAGAGAACCCTTTCTTTCACTGTTTGGTGG
CAGAGATTATCCCAGCACCTGGGGAGTCACAAGGGTCCCTTGTGGTGGGCTATGGGCTGTACTA
CTTCATCTATAGCACATGGACCGGACGAAACGTTTATCTGGAAGACATCTATGTGATGCCGCAA
TATCGGGGTACTGGCTGGGGCTAAGGATGGACAGAATGCCCACAGACCCAATGAACAGTCCTCA
GACCTATCCCATTACCCCAACCTCAGATTATAGTTTCCTTTGATACCCTTTCAACTCAAATAAT
AGTCCTTCCTGTCCCTTTCTCCACTATAGGTCAAGGGATTGGTACCAAAATAATCAAAAAGGTG
GCTGAGGTGAGCAAAGGGGTGGGGCTTACAAACTAGTTACCGCCCCCAAACGAAAGCCAGCCAG
TCAGCCAAACCATCAATCAATCAATCAATCAATCAGTCACGTAAGTGGGAGTGTCGAGGTTGAA
TGAGGGGGATGAGAAAGATTTTTCTTTTTATTGTTTGTTGTTCAAGACAGGGTTTCTCTGTGTA
GTCCTGATTGTCCTAGAACTTGCTCTGTAGACCAGGCTGGCCTCCAACTCAGAGGTCTGCCTGC
CTCTGCAGGAATTAAAGGTGCTGGGATTAAAGGTGTGTGCCAGCCATTAAAAAAAAAAAAAAAA
AA

hide sequence

RefSeq Acc Id:

NM_026991 ⟹ NP_081267

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	69,512,878 - 69,514,704 (+)	NCBI
GRCm38	11	69,622,052 - 69,623,878 (+)	NCBI
MGSCv37	11	69,435,611 - 69,437,371 (+)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

AGAATTTAAGGCCTTTTCTGGCAGAAGAGACCACCAGGCCGGCTAATCCTCCCAGCTGAGACCG
GTTGGTGCCAGAATCTTGTCTAGAAGCTTCTAGCATTTCTTCTGCCCCTCGCTCCCAGCACTTT
GAGACCTGAGCTTTGAGACCAGACCTCCGCGGTTCTGCAAACGTGGGAGTTGTCTGTGATCTTT
GATTTTTGACAGTGAGGCTCGGAATGGCTTCCACGCGAATCCGAGAGGCCAGGGAGAGCGATTG
TGGAGACATTATGAGGATGATCCGGGAACTGGCAGAGTTCGAGAAACTGTCCCATCAGGTGAAG
ATCAGTGAAGAAGCTCTGCGAGCAGATGGCTTTGGAGAGAACCCTTTCTTTCACTGTTTGGTGG
CAGAGATTATCCCAGCACCTGGGGAGTCACAAGGGTCCCTTGTGGTGGGCTATGGGCTGTACTA
CTTCATCTATAGCACATGGACCGGACGAAACGTTTATCTGGAAGACATCTATGTGATGCCGCAA
TATCGGGGTCAAGGGATTGGTACCAAAATAATCAAAAAGGTGGCTGAGGTTGCCCTGAATAAGG
GTTGCTCCCAGTTCCGCCTGGCAGTTCTGGATTGGAACAAGAAGGCCGTGAACTTGTACAAATT
TCTAGGGGCTCAAGATCTGACTGAATCGGAAGGCTGGCTCTCCTTTCGATTTGAAGGCGAGGCA
ATGAGGGAGTTGGCAGGACGCTGACTTACGCCCTCTCTCTCCTGCCTCTTCTTTGGGATCACCA
TATCAAGTTTTCCTAAGACCATAACCATAGGCACTGACCCAGACAGACGCTCGCTCACCCAGAG
GCCTCCCAGGGTGCAGACTCCTGAAGTACAGAAAGAGTGGAAGAGGGAGAAGCCTTATTAGGAA
CCACAAATAAAATACTTGCTTTGCCCTCATGGGTAGAGGATGTGATGCTGCAAAAA

hide sequence

RefSeq Acc Id:

XM_006534110 ⟹ XP_006534173

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	69,512,826 - 69,514,857 (+)	NCBI
GRCm38	11	69,621,998 - 69,624,032 (+)	NCBI

Sequence:

show sequence

GAAATGGTCGTAAGCAGCAAGCTGATTGGCTGCAGGGAGGCCCGGAGGGGGCTCAGAATTTAAG
GCCTTTTCTGGCAGAAGAGACCACCAGGCCGGCTAATCCTCCCAGCTGAGACCGGTTGGTGCCA
GAATCTTGTCTAGAAGCTTCTAGCATTTCTTCTGCCCCTCGCTCCCAGCACTTTGAGACCTGAG
CTTTGAGACCAGACCTCCGCGGTTCTGCAAACGTGGGAGTTGTCTGTGATCTTTGATTTTTGAC
AGTGAGGCTCGGAATGGCTTCCACGCGAATCCGAGAGGCCAGGGAGAGCGATTGTGGAGACATT
ATGAGGATGATCCGGGAACTGGCAGAGTTCGAGAAACTGTCCCATCAGGTGAAGATCAGTGAAG
AAGCTCTGCGAGCAGATGGCTTTGGAGAGAACCCTTTCTTTCACTGTTTGGTGGCAGAGATTAT
CCCAGCACCTGGGGAGTCACAAGGTAAGGAAGCCTGCAGTTATCCTCCGTGTTTTTCCTCCCAA
AAGCCTCACTCTTCTCTCTCATTTTCAGGGTCCCTTGTGGTGGGCTATGGGCTGTACTACTTCA
TCTATAGCACATGGACCGGACGAAACGTTTATCTGGAAGACATCTATGTGATGCCGCAATATCG
GGGTCAAGGGATTGGTACCAAAATAATCAAAAAGGTGGCTGAGGTTGCCCTGAATAAGGGTTGC
TCCCAGTTCCGCCTGGCAGTTCTGGATTGGAACAAGAAGGCCGTGAACTTGTACAAATTTCTAG
GGGCTCAAGATCTGACTGAATCGGAAGGCTGGCTCTCCTTTCGATTTGAAGGCGAGGCAATGAG
GGAGTTGGCAGGACGCTGACTTACGCCCTCTCTCTCCTGCCTCTTCTTTGGGATCACCATATCA
AGTTTTCCTAAGACCATAACCATAGGCACTGACCCAGACAGACGCTCGCTCACCCAGAGGCCTC
CCAGGGTGCAGACTCCTGAAGTACAGAAAGAGTGGAAGAGGGAGAAGCCTTATTAGGAACCACA
AATAAAATACTTGCTTTGCCCTCATGGGTAGAGGATGTGATGCTGCAGCCATTTTGAAGCCCTT
CTATTTGAACATTGTTCTGATGAGGGCTGGGACAGCCAAAGAGGCAGGGGTCATGGAGGCCTCA
AGGACTCTGGGCACCCTAGTCTTGCCTCTAGCCTGTTAGAAAAAAAAAAAAAAAAAAAAAAAGA
ACAAGAGGG

hide sequence

RefSeq Acc Id:

XM_006534111 ⟹ XP_006534174

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	69,512,824 - 69,514,857 (+)	NCBI
GRCm38	11	69,621,996 - 69,624,032 (+)	NCBI

Sequence:

show sequence

GGGAAATGGTCGTAAGCAGCAAGCTGATTGGCTGCAGGGAGGCCCGGAGGGGGCTCAGAATTTA
AGGCCTTTTCTGGCAGAAGAGACCACCAGGCCGGCTAATCCTCCCAGCTGAGACCGTGAGGCTC
GGAATGGCTTCCACGCGAATCCGAGAGGCCAGGGAGAGCGATTGTGGAGACATTATGAGGATGA
TCCGGGAACTGGCAGAGTTCGAGAAACTGTCCCATCAGGTGAAGATCAGTGAAGAAGCTCTGCG
AGCAGATGGCTTTGGAGAGAACCCTTTCTTTCACTGTTTGGTGGCAGAGATTATCCCAGCACCT
GGGGAGTCACAAGGTAAGGAAGCCTGCAGTTATCCTCCGTGTTTTTCCTCCCAAAAGCCTCACT
CTTCTCTCTCATTTTCAGGGTCCCTTGTGGTGGGCTATGGGCTGTACTACTTCATCTATAGCAC
ATGGACCGGACGAAACGTTTATCTGGAAGACATCTATGTGATGCCGCAATATCGGGGTCAAGGG
ATTGGTACCAAAATAATCAAAAAGGTGGCTGAGGTTGCCCTGAATAAGGGTTGCTCCCAGTTCC
GCCTGGCAGTTCTGGATTGGAACAAGAAGGCCGTGAACTTGTACAAATTTCTAGGGGCTCAAGA
TCTGACTGAATCGGAAGGCTGGCTCTCCTTTCGATTTGAAGGCGAGGCAATGAGGGAGTTGGCA
GGACGCTGACTTACGCCCTCTCTCTCCTGCCTCTTCTTTGGGATCACCATATCAAGTTTTCCTA
AGACCATAACCATAGGCACTGACCCAGACAGACGCTCGCTCACCCAGAGGCCTCCCAGGGTGCA
GACTCCTGAAGTACAGAAAGAGTGGAAGAGGGAGAAGCCTTATTAGGAACCACAAATAAAATAC
TTGCTTTGCCCTCATGGGTAGAGGATGTGATGCTGCAGCCATTTTGAAGCCCTTCTATTTGAAC
ATTGTTCTGATGAGGGCTGGGACAGCCAAAGAGGCAGGGGTCATGGAGGCCTCAAGGACTCTGG
GCACCCTAGTCTTGCCTCTAGCCTGTTAGAAAAAAAAAAAAAAAAAAAAAAAGAACAAGAGGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001343397	(Get FASTA)	NCBI Sequence Viewer
	NP_001343398	(Get FASTA)	NCBI Sequence Viewer
	NP_081267	(Get FASTA)	NCBI Sequence Viewer
	XP_006534173	(Get FASTA)	NCBI Sequence Viewer
	XP_006534174	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH61227	(Get FASTA)	NCBI Sequence Viewer
	BAE36254	(Get FASTA)	NCBI Sequence Viewer
	CAI52020	(Get FASTA)	NCBI Sequence Viewer
	Q6P8J2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_081267 ⟸ NM_026991
- Peptide Label:	isoform 1
- UniProtKB:	Q6P8J2 (UniProtKB/Swiss-Prot), A0A158SIT0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASTRIREARESDCGDIMRMIRELAEFEKLSHQVKISEEALRADGFGENPFFHCLVAEIIPAPG ESQGSLVVGYGLYYFIYSTWTGRNVYLEDIYVMPQYRGQGIGTKIIKKVAEVALNKGCSQFRLA VLDWNKKAVNLYKFLGAQDLTESEGWLSFRFEGEAMRELAGR hide sequence

RefSeq Acc Id:	XP_006534174 ⟸ XM_006534111
- Peptide Label:	isoform X1
- Sequence:	show sequence MASTRIREARESDCGDIMRMIRELAEFEKLSHQVKISEEALRADGFGENPFFHCLVAEIIPAPG ESQGKEACSYPPCFSSQKPHSSLSFSGSLVVGYGLYYFIYSTWTGRNVYLEDIYVMPQYRGQGI GTKIIKKVAEVALNKGCSQFRLAVLDWNKKAVNLYKFLGAQDLTESEGWLSFRFEGEAMRELAG R hide sequence

RefSeq Acc Id:	XP_006534173 ⟸ XM_006534110
- Peptide Label:	isoform X1
- Sequence:	show sequence MASTRIREARESDCGDIMRMIRELAEFEKLSHQVKISEEALRADGFGENPFFHCLVAEIIPAPG ESQGKEACSYPPCFSSQKPHSSLSFSGSLVVGYGLYYFIYSTWTGRNVYLEDIYVMPQYRGQGI GTKIIKKVAEVALNKGCSQFRLAVLDWNKKAVNLYKFLGAQDLTESEGWLSFRFEGEAMRELAG R hide sequence

RefSeq Acc Id:	NP_001343397 ⟸ NM_001356468
- Peptide Label:	isoform 1

RefSeq Acc Id:	NP_001343398 ⟸ NM_001356469
- Peptide Label:	isoform 2

RefSeq Acc Id:

ENSMUSP00000090647 ⟸ ENSMUST00000092969

RefSeq Acc Id:

ENSMUSP00000104296 ⟸ ENSMUST00000108656

Protein Domains

N-acetyltransferase

Promoters

RGD ID:

6822027

Promoter ID:

MM_KWN:8085

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Liver, MEF_B4

Transcripts:

ENSMUST00000092969, OTTMUST00000013450, OTTMUST00000062238

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	69,435,279 - 69,435,779 (+)	MPROMDB

RGD ID:

8675190

Promoter ID:

EPDNEW_M15626

Type:

initiation region

Name:

Sat2_1

Description:

Mus musculus spermidine/spermine N1-acetyl transferase 2 , transcriptvariant 1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	11	69,622,052 - 69,622,112	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1916465	AgrOrtholog
Ensembl Genes	ENSMUSG00000069835	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSMUSP00000090647	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000104296	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000092969	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000108656	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000151255	ENTREZGENE
InterPro	Acyl_CoA_acyltransferase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GNAT_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAT2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:69215	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1916465	ENTREZGENE
NCBI Gene	69215	ENTREZGENE
PANTHER	PTHR10545:SF51	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Acetyltransf_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Sat2	PhenoGen
PROSITE	GNAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF55729	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A158SIT0	ENTREZGENE, UniProtKB/TrEMBL
	Q3TTS0_MOUSE	UniProtKB/TrEMBL
	Q6P8J2	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q5F299	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)