Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kdsr (3-ketodihydrosphingosine reductase) Mus musculus
Symbol: Kdsr
Name: 3-ketodihydrosphingosine reductase
Description: Predicted to have 3-dehydrosphinganine reductase activity. Involved in sphingolipid biosynthetic process. Predicted to localize to the endoplasmic reticulum and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 4 and follicular lymphoma. Orthologous to human KDSR (3-ketodihydrosphingosine reductase); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 1,2-dichloroethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3-dehydrosphinganine reductase; 6330410P18Rik; 9430079B08Rik; follicular lymphoma variant translocation 1; follicular variant translocation protein 1 homolog; FVT-1; Fvt1; KDS reductase; RIKEN cDNA 9430079B08 gene
Homo sapiens (human) : KDSR (3-ketodihydrosphingosine reductase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdsr (3-ketodihydrosphingosine reductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdsr (3-ketodihydrosphingosine reductase)
Pan paniscus (bonobo/pygmy chimpanzee) : KDSR (3-ketodihydrosphingosine reductase)
Canis lupus familiaris (dog) : KDSR (3-ketodihydrosphingosine reductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdsr (3-ketodihydrosphingosine reductase)
Sus scrofa (pig) : KDSR (3-ketodihydrosphingosine reductase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1106,720,459 - 106,759,727 (-)Ensembl
GRCm381106,720,410 - 106,759,742 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371108,616,987 - 108,656,319 (-)NCBIGRCm37mm9NCBIm37
MGSCv361108,551,436 - 108,587,347 (-)NCBImm8
Celera1109,569,745 - 109,609,088 (-)NCBICelera
Cytogenetic Map1 E2.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Kdsr
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317162
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.