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Gene: Recql4 (RecQ protein-like 4) Mus musculus
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Symbol: Recql4
Name: RecQ protein-like 4
Description: Predicted to have ATP binding activity; DNA binding activity; and nucleoside-triphosphatase activity. Involved in several processes, including negative regulation of sister chromatid cohesion; positive regulation of cell population proliferation; and skeletal system morphogenesis. Predicted to localize to chromosome, telomeric region; cytoplasm; and nucleus. Used to study Rothmund-Thomson syndrome. Human ortholog(s) of this gene implicated in Baller-Gerold syndrome; Rothmund-Thomson syndrome; and rapadilino syndrome. Is expressed in several structures, including Harderian gland; alimentary system; immune system; male reproductive gland or organ; and nervous system. Orthologous to human RECQL4 (RecQ like helicase 4); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-dependent DNA helicase Q4; DNA helicase, RecQ-like type 4; RecQ helicase protein-like 4; RecQ4
Orthologs:
Homo sapiens (human) : RECQL4 (RecQ like helicase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Recql4 (RecQ like helicase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Recql4 (RecQ like helicase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : RECQL4 (RecQ like helicase 4)
Canis lupus familiaris (dog) : RECQL4 (RecQ like helicase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Recql4 (RecQ like helicase 4)
Sus scrofa (pig) : RECQL4 (RecQ like helicase 4)
Chlorocebus sabaeus (African green monkey) : RECQL4 (RecQ like helicase 4)
Heterocephalus glaber (naked mole-rat) : Recql4 (RecQ like helicase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1576,703,553 - 76,710,548 (-)EnsemblGRCm38mm10GRCm38
GRCm381576,703,553 - 76,710,616 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371576,534,171 - 76,540,906 (-)NCBIGRCm37mm9NCBIm37
MGSCv361576,530,996 - 76,537,731 (-)NCBImm8
Celera1578,197,351 - 78,204,086 (-)NCBICelera
Cytogenetic Map15D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Recql4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317097
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.