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Gene: Recql4 (RecQ protein-like 4) Mus musculus
Symbol: Recql4
Name: RecQ protein-like 4
Description: Predicted to have ATP binding activity; DNA binding activity; and nucleoside-triphosphatase activity. Involved in several processes, including negative regulation of sister chromatid cohesion; positive regulation of cell population proliferation; and skeletal system morphogenesis. Predicted to localize to chromosome, telomeric region; cytoplasm; and nucleus. Used to study Rothmund-Thomson syndrome. Human ortholog(s) of this gene implicated in Baller-Gerold syndrome; Rothmund-Thomson syndrome; and rapadilino syndrome. Is expressed in several structures, including Harderian gland; alimentary system; immune system; male reproductive gland or organ; and nervous system. Orthologous to human RECQL4 (RecQ like helicase 4); INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-dependent DNA helicase Q4; DNA helicase, RecQ-like type 4; RecQ helicase protein-like 4; RecQ4
Homo sapiens (human) : RECQL4 (RecQ like helicase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Recql4 (RecQ like helicase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Recql4 (RecQ like helicase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : RECQL4 (RecQ like helicase 4)
Canis lupus familiaris (dog) : RECQL4 (RecQ like helicase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Recql4 (RecQ like helicase 4)
Sus scrofa (pig) : RECQL4 (RecQ like helicase 4)
Chlorocebus sabaeus (African green monkey) : RECQL4 (RecQ like helicase 4)
Heterocephalus glaber (naked mole-rat) : Recql4 (RecQ like helicase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1576,703,553 - 76,710,548 (-)EnsemblGRCm38mm10GRCm38
GRCm381576,703,553 - 76,710,616 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371576,534,171 - 76,540,906 (-)NCBIGRCm37mm9NCBIm37
MGSCv361576,530,996 - 76,537,731 (-)NCBImm8
Celera1578,197,351 - 78,204,086 (-)NCBICelera
Cytogenetic Map15D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Recql4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317097
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.