Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CD3G (CD3g molecule) Homo sapiens
Symbol: CD3G
Name: CD3g molecule
Description: The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD3-GAMMA; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); FLJ17620; FLJ17664; FLJ79544; FLJ94613; IMD17; MGC138597; T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain; T3G
Mus musculus (house mouse) : Cd3g (CD3 antigen, gamma polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd3g (CD3g molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd3g (CD3g molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD3G (CD3g molecule)
Canis lupus familiaris (dog) : CD3G (CD3g molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd3g (CD3g molecule)
Sus scrofa (pig) : CD3G (CD3g molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3811118,344,344 - 118,353,782 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,215,032 - 118,224,497 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,720,311 - 117,729,261 (+)NCBINCBI36hg18NCBI36
Build 3411117,720,310 - 117,729,261NCBI
Celera11115,372,928 - 115,382,366 (+)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11114,148,956 - 114,158,393 (+)NCBIHuRef
CHM1_111118,101,492 - 118,110,943 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CD3G
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317072
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.