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Gene: Pak4 (p21 (RAC1) activated kinase 4) Mus musculus
Symbol: Pak4
Name: p21 (RAC1) activated kinase 4
RGD ID: 1317049
Description: Exhibits protein kinase activity. Involved in cellular response to organic cyclic compound and dendritic spine development. Predicted to localize to cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PAK4 (p21 (RAC1) activated kinase 4); PARTICIPATES IN fibroblast growth factor signaling pathway; epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730488L07Rik; AW555722; mKIAA1142; p21 protein (Cdc42/Rac)-activated kinase 4; p21-activated kinase 4; PAK-4; serine/threonine-protein kinase PAK 4
Homo sapiens (human) : PAK4 (p21 (RAC1) activated kinase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pak4 (p21 (RAC1) activated kinase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pak4 (p21 (RAC1) activated kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK4 (p21 (RAC1) activated kinase 4)
Canis lupus familiaris (dog) : PAK4 (p21 (RAC1) activated kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pak4 (p21 (RAC1) activated kinase 4)
Sus scrofa (pig) : PAK4 (p21 (RAC1) activated kinase 4)
Chlorocebus sabaeus (African green monkey) : PAK4 (p21 (RAC1) activated kinase 4)
Heterocephalus glaber (naked mole-rat) : Pak4 (p21 (RAC1) activated kinase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39728,258,244 - 28,297,609 (-)NCBI
GRCm38728,558,819 - 28,598,184 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl728,558,819 - 28,598,185 (-)EnsemblGRCm38mm10GRCm38
MGSCv37729,343,838 - 29,383,203 (-)NCBIGRCm37mm9NCBIm37
MGSCv36728,267,579 - 28,306,906 (-)NCBImm8
Celera723,123,936 - 23,163,272 (-)NCBICelera
Cytogenetic Map7B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Pak4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317049
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.