Gkn3 (gastrokine 3) - Rat Genome Database
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Gene: Gkn3 (gastrokine 3) Mus musculus
Analyze
Symbol: Gkn3
Name: gastrokine 3
RGD ID: 1316989
MGI Page MGI
Description: Orthologous to human GKN3P (gastrokine 3, pseudogene); INTERACTS WITH 4-hydroxyphenyl retinamide; carbon nanotube; genistein.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1190003M12Rik; gastrokine-3
RGD Orthologs
Human
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,360,301 - 87,365,917 (-)NCBIGRCm39mm39
GRCm39 Ensembl687,360,238 - 87,365,917 (-)Ensembl
GRCm38687,383,319 - 87,388,935 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,383,256 - 87,388,935 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,333,313 - 87,338,929 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,348,902 - 87,354,488 (-)NCBImm8
Celera689,322,371 - 89,327,983 (-)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:20138039   PMID:21267068  
PMID:21677750   PMID:21873635   PMID:23715263   PMID:28604600  


Genomics

Comparative Map Data
Gkn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,360,301 - 87,365,917 (-)NCBIGRCm39mm39
GRCm39 Ensembl687,360,238 - 87,365,917 (-)Ensembl
GRCm38687,383,319 - 87,388,935 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,383,256 - 87,388,935 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,333,313 - 87,338,929 (-)NCBIGRCm37mm9NCBIm37
MGSCv36687,348,902 - 87,354,488 (-)NCBImm8
Celera689,322,371 - 89,327,983 (-)NCBICelera
Cytogenetic Map6D1NCBI
GKN3P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl268,921,248 - 68,926,834 (+)EnsemblGRCh38hg38GRCh38
GRCh38268,922,505 - 68,926,834 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37269,149,637 - 69,153,966 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36268,955,254 - 69,013,138 (+)NCBINCBI36hg18NCBI36
Celera269,000,141 - 69,004,470 (+)NCBI
Cytogenetic Map2p13.3NCBI
HuRef268,885,898 - 68,890,227 (+)NCBIHuRef
CHM1_1269,078,994 - 69,083,323 (+)NCBICHM1_1
Gkn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24119,828,859 - 119,833,924 (-)NCBI
Rnor_6.0 Ensembl4119,182,135 - 119,188,251 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04119,181,970 - 119,188,356 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04183,750,767 - 183,756,952 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,535,051 - 121,540,818 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4108,799,271 - 108,805,834 (-)NCBICelera
Cytogenetic Map4q34NCBI
GKN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl373,461,798 - 73,466,798 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1373,461,801 - 73,468,111 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2376,903,101 - 76,909,413 (-)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:130
Count of miRNA genes:123
Interacting mature miRNAs:127
Transcripts:ENSMUST00000032127
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000032127   ⟹   ENSMUSP00000032127
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl687,383,256 - 87,388,935 (-)Ensembl
RefSeq Acc Id: NM_026860   ⟹   NP_081136
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39687,360,301 - 87,365,917 (-)NCBI
GRCm38687,383,319 - 87,388,935 (-)ENTREZGENE
MGSCv37687,333,313 - 87,338,929 (-)RGD
Celera689,322,371 - 89,327,983 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_081136   ⟸   NM_026860
- Peptide Label: precursor
- UniProtKB: Q9D0T7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000032127   ⟸   ENSMUST00000032127
Protein Domains
BRICHOS

Promoters
RGD ID:6890326
Promoter ID:EPDNEW_M8614
Type:multiple initiation site
Name:Gkn3_1
Description:Mus musculus gastrokine 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38687,388,854 - 87,388,914EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916138 AgrOrtholog
Ensembl Genes ENSMUSG00000030048 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000032127 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000032127 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro BRICHOS_dom UniProtKB/Swiss-Prot
KEGG Report mmu:68888 UniProtKB/Swiss-Prot
MGD MGI:1916138 ENTREZGENE
NCBI Gene 68888 ENTREZGENE
Pfam BRICHOS UniProtKB/Swiss-Prot
PhenoGen Gkn3 PhenoGen
PROSITE BRICHOS UniProtKB/Swiss-Prot
SMART BRICHOS UniProtKB/Swiss-Prot
UniProt GKN3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE