Dppa1 (developmental pluripotency associated 1) - Rat Genome Database
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Gene: Dppa1 (developmental pluripotency associated 1) Mus musculus
Analyze
No known orthologs.
Symbol: Dppa1
Name: developmental pluripotency associated 1
RGD ID: 1316975
MGI Page MGI
Description: Predicted to have phosphatidylserine binding activity and virus receptor activity. Predicted to be involved in phagocytosis, engulfment and positive regulation of mast cell activation. Predicted to localize to cell surface. Is expressed in several structures, including 2-cell stage embryo; adrenal gland; genitourinary system; gut; and nervous system; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C77727
RGD Orthologs
Alliance Genes
More Info homologs ...
Related Pseudogenes: Gm12171  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391146,497,837 - 46,520,249 (-)NCBIGRCm39mm39
GRCm381146,607,010 - 46,629,274 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1146,607,772 - 46,629,261 (-)EnsemblGRCm38mm10GRCm38
MGSCv371146,420,512 - 46,442,776 (-)NCBIGRCm37mm9NCBIm37
MGSCv361146,451,876 - 46,472,684 (-)NCBImm8
Celera1151,189,552 - 51,211,737 (-)NCBICelera
Cytogenetic Map11B1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (IBA)

Molecular Function

References

References - curated
1. RGD automated import pipeline
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12620990   PMID:16141072   PMID:16141073   PMID:16602821  
PMID:21267068   PMID:21677750   PMID:21731673   PMID:21873635   PMID:24194600   PMID:24859004   PMID:27626380  


Genomics

Position Markers
RH126228  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381146,607,946 - 46,608,163UniSTSGRCm38
GRCm381146,556,739 - 46,556,956UniSTSGRCm38
MGSCv371146,421,448 - 46,421,665UniSTSGRCm37
MGSCv371146,370,241 - 46,370,458UniSTSGRCm37
Celera1151,137,034 - 51,137,251UniSTS
Celera1151,190,489 - 51,190,706UniSTS
Cytogenetic Map11B1.1UniSTS
Dppa1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B1.1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111868778952687889Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111868778952687889Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111868778952687889Mouse
12801460Intim2_mintima modifier 2 (mouse)111868778952687889Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111939175053391888Mouse
14746971Manh70_mmandible shape 70 (mouse)112001506354015063Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2127257955272579Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112588179959881914Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112724805750745267Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112724805750745267Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112724805750745267Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112724805750745267Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112724805750745267Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
1300569Eae6b_msusceptibility to experimental allergic encephalomyelitis 6b (mouse)Not determined114005990154203622Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined114005990154203622Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114288179954190238Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:350
Count of miRNA genes:282
Interacting mature miRNAs:294
Transcripts:ENSMUST00000077173, ENSMUST00000109227
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000077173   ⟹   ENSMUSP00000076416
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1146,607,772 - 46,629,261 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109227   ⟹   ENSMUSP00000104850
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1146,608,710 - 46,629,261 (-)Ensembl
RefSeq Acc Id: NM_001163358   ⟹   NP_001156830
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391146,497,837 - 46,520,101 (-)NCBI
GRCm381146,607,010 - 46,629,274 (-)NCBI
MGSCv371146,420,512 - 46,442,776 (-)RGD
Celera1151,189,552 - 51,211,737 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_178247   ⟹   NP_839978
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391146,497,837 - 46,520,101 (-)NCBI
GRCm381146,607,010 - 46,629,274 (-)NCBI
MGSCv371146,420,512 - 46,442,776 (-)RGD
Celera1151,189,552 - 51,211,737 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017314620   ⟹   XP_017170109
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391146,499,285 - 46,520,101 (-)NCBI
GRCm381146,608,458 - 46,629,274 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156789   ⟹   XP_036012682
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391146,499,285 - 46,520,249 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_839978   ⟸   NM_178247
- Peptide Label: precursor
- UniProtKB: Q810Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001156830   ⟸   NM_001163358
- Peptide Label: precursor
- UniProtKB: Q810Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017170109   ⟸   XM_017314620
- Peptide Label: isoform X1
- UniProtKB: Q3TL00 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000104850   ⟸   ENSMUST00000109227
RefSeq Acc Id: ENSMUSP00000076416   ⟸   ENSMUST00000077173
RefSeq Acc Id: XP_036012682   ⟸   XM_036156789
- Peptide Label: isoform X1

Promoters
RGD ID:8674412
Promoter ID:EPDNEW_M15237
Type:single initiation site
Name:Dppa1_1
Description:Mus musculus developmental pluripotency associated 1 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381146,629,274 - 46,629,334EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2157522 AgrOrtholog
Ensembl Genes ENSMUSG00000064010 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000076416 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000104850 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000077173 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000109227 ENTREZGENE, UniProtKB/TrEMBL
KEGG Report mmu:347708 UniProtKB/TrEMBL
MGD MGI:2157522 ENTREZGENE
NCBI Gene 347708 ENTREZGENE
PhenoGen Dppa1 PhenoGen
UniGene Mm.18119 ENTREZGENE
UniProt Q3TL00 ENTREZGENE, UniProtKB/TrEMBL
  Q810Y7 ENTREZGENE, UniProtKB/TrEMBL