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Gene: CHAF1B (chromatin assembly factor 1 subunit B) Homo sapiens
Symbol: CHAF1B
Name: chromatin assembly factor 1 subunit B
RGD ID: 1316940
Description: Predicted to have chromatin binding activity and unfolded protein binding activity. Involved in DNA replication-dependent nucleosome assembly. Localizes to CAF-1 complex; nuclear chromatin; and nucleoplasm. Colocalizes with cytosol. Biomarker of glioblastoma multiforme; malignant glioma; oral squamous cell carcinoma; prostate cancer; and skin melanoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAF-1; CAF-1 subunit B; CAF-I 60 kDa subunit; CAF-I p60; CAF-IP60; CAF1; CAF1A; CAF1P60; chromatin assembly factor 1, subunit B (p60); chromatin assembly factor I p60 subunit; human chromatin assembly factor-I p60 subunit; M-phase phosphoprotein 7; MPHOSPH7; MPP7
Mus musculus (house mouse) : Chaf1b (chromatin assembly factor 1, subunit B (p60))  MGI  Alliance
Rattus norvegicus (Norway rat) : Chaf1b (chromatin assembly factor 1 subunit B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chaf1b (chromatin assembly factor 1 subunit B)
Pan paniscus (bonobo/pygmy chimpanzee) : CHAF1B (chromatin assembly factor 1 subunit B)
Canis lupus familiaris (dog) : CHAF1B (chromatin assembly factor 1 subunit B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chaf1b (chromatin assembly factor 1 subunit B)
Sus scrofa (pig) : CHAF1B (chromatin assembly factor 1 subunit B)
Chlorocebus sabaeus (African green monkey) : CHAF1B (chromatin assembly factor 1 subunit B)
Heterocephalus glaber (naked mole-rat) : Chaf1b (chromatin assembly factor 1 subunit B)
more info ...
Related Pseudogenes: LOC100130683  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2136,385,392 - 36,419,015 (+)EnsemblGRCh38hg38GRCh38
GRCh382136,380,145 - 36,419,015 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372137,757,689 - 37,789,125 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,679,559 - 36,710,995 (+)NCBINCBI36hg18NCBI36
Build 342136,679,558 - 36,710,994NCBI
Celera2122,956,076 - 22,987,501 (+)NCBI
Cytogenetic Map21q22.12-q22.13NCBI
HuRef2123,233,429 - 23,264,863 (+)NCBIHuRef
CHM1_12137,319,551 - 37,350,873 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHAF1B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316940
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.