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Gene: GRAP2 (GRB2 related adaptor protein 2) Homo sapiens
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Symbol: GRAP2
Name: GRB2 related adaptor protein 2
Description: Predicted to be involved in several processes, including Ras protein signal transduction; T cell costimulation; and immune response-regulating cell surface receptor signaling pathway. Localizes to several cellular components, including cytosol; endosome; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adapter protein GRID; GADS; GRAP-2; GRB-2-like protein; GRB2-related adapter protein 2; GRB2-related adaptor protein 2; GRB2-related protein with insert domain; GRB2L; GRBLG; GrbX; grf-40; Grf40; grf40 adapter protein; GRID; growth factor receptor-binding protein; growth factor receptor-bound protein 2-related adaptor protein 2; GRPL; hematopoietic cell-associated adapter protein GrpL; hematopoietic cell-associated adaptor protein GRPL; Mona; P38; SH3-SH2-SH3 adapter Mona; SH3-SH2-SH3 adaptor molecule
Orthologs:
Mus musculus (house mouse) : Grap2 (GRB2-related adaptor protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Grap2 (GRB2-related adaptor protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grap2 (GRB2 related adaptor protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GRAP2 (GRB2 related adaptor protein 2)
Canis lupus familiaris (dog) : GRAP2 (GRB2 related adaptor protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grap2 (GRB2 related adaptor protein 2)
Sus scrofa (pig) : GRAP2 (GRB2 related adaptor protein 2)
Chlorocebus sabaeus (African green monkey) : GRAP2 (GRB2 related adaptor protein 2)
Heterocephalus glaber (naked mole-rat) : Grap2 (GRB2 related adaptor protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2239,901,084 - 39,973,721 (+)EnsemblGRCh38hg38GRCh38
GRCh382239,901,073 - 39,973,721 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372240,297,086 - 40,369,347 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,627,032 - 38,697,330 (+)NCBINCBI36hg18NCBI36
Build 342238,621,585 - 38,691,884NCBI
Celera2224,099,151 - 24,169,444 (+)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2223,260,094 - 23,330,327 (+)NCBIHuRef
CHM1_12240,256,126 - 40,328,553 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GRAP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316895
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.