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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FLII mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FLII mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FLII mRNA | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FLII mRNA] | CTD | PMID:15034205 | 2,4-dinitrotoluene | affects expression | ISO | RGD:1307590 | 6480464 | 2, 4-dinitrotoluene affects the expression of FLII mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | RGD:1307590 | 6480464 | 2, 6-dinitrotoluene affects the expression of FLII mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | ISO | RGD:1316872 | 6480464 | beta-methylcholine affects the expression of FLII mRNA | CTD | PMID:21179406 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of FLII mRNA | CTD | PMID:18648102 | acetamide | increases expression | ISO | RGD:1307590 | 6480464 | acetamide results in increased expression of FLII mRNA | CTD | PMID:31881176 | acetylsalicylic acid | decreases expression | ISO | RGD:1316872 | 6480464 | Aspirin results in decreased expression of FLII mRNA | CTD | PMID:15928584 | acrolein | multiple interactions | ISO | RGD:1316872 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of FLII mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of FLII mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | RGD:1316872 | 6480464 | Aflatoxin B1 results in decreased methylation of FLII gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | RGD:1316872 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of FLII mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of FLII mRNA | CTD | PMID:32699268 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in decreased expression of FLII mRNA, AHR protein inhibits the reaction [Benzoapyrene results in decreased expression of FLII mRNA] | CTD | PMID:15034205, PMID:27858113 | benzo[a]pyrene | decreases methylation | ISO | RGD:1316872 | 6480464 | Benzoapyrene results in decreased methylation of FLII promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzoapyrene results in decreased expression of FLII mRNA | CTD | PMID:15034205 | benzo[b]fluoranthene | multiple interactions | EXP | | 6480464 | [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in decreased expression of FLII mRNA | CTD | PMID:27858113 | bisphenol A | increases expression | ISO | RGD:1307590 | 6480464 | bisphenol A results in increased expression of FLII mRNA | CTD | PMID:25181051 | bisphenol A | affects expression | ISO | RGD:1316872 | 6480464 | bisphenol A affects the expression of FLII mRNA | CTD | PMID:30903817 | bisphenol A | decreases expression | ISO | RGD:1316872 | 6480464 | bisphenol A results in decreased expression of FLII mRNA | CTD | PMID:29275510 | bisphenol A | decreases expression | ISO | RGD:1307590 | 6480464 | bisphenol A results in decreased expression of FLII mRNA | CTD | PMID:30816183 | bromobenzene | increases expression | ISO | RGD:1307590 | 6480464 | bromobenzene results in increased expression of FLII mRNA | CTD | PMID:12628495, PMID:16036859 | capecitabine | decreases response to substance | ISO | RGD:1316872 | 6480464 | FLII protein results in decreased susceptibility to Capecitabine | CTD | PMID:16734730 | chrysene | multiple interactions | EXP | | 6480464 | [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in decreased expression of FLII mRNA | CTD | PMID:27858113 | cisplatin | multiple interactions | ISO | RGD:1316872 | 6480464 | [Piroxicam co-treated with Cisplatin] results in decreased expression of FLII mRNA | CTD | PMID:21858171 | cobalt dichloride | increases expression | ISO | RGD:1316872 | 6480464 | cobaltous chloride results in increased expression of FLII mRNA | CTD | PMID:19376846 | cyclosporin A | increases expression | ISO | RGD:1316872 | 6480464 | Cyclosporine results in increased expression of FLII mRNA | CTD | PMID:20106945, PMID:25562108 | diazinon | increases methylation | ISO | RGD:1316872 | 6480464 | Diazinon results in increased methylation of FLII gene | CTD | PMID:22964155 | dicrotophos | increases expression | ISO | RGD:1316872 | 6480464 | dicrotophos results in increased expression of FLII mRNA | CTD | PMID:28302478 | doxifluridine | decreases response to substance | ISO | RGD:1316872 | 6480464 | FLII protein results in decreased susceptibility to doxifluridine | CTD | PMID:16734730 | doxorubicin | decreases expression | ISO | RGD:1316872 | 6480464 | Doxorubicin results in decreased expression of FLII mRNA | CTD | PMID:29803840 | elemental selenium | increases expression | ISO | RGD:1316872 | 6480464 | Selenium results in increased expression of FLII mRNA | CTD | PMID:19244175 | folic acid | multiple interactions | EXP | | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FLII mRNA | CTD | PMID:22206623 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of FLII mRNA | CTD | PMID:25629700 | ozone | multiple interactions | ISO | RGD:1316872 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of FLII mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of FLII mRNA | CTD | PMID:17562736 | pentachlorophenol | decreases expression | EXP | | 6480464 | Pentachlorophenol results in decreased expression of FLII mRNA | CTD | PMID:23892564 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of FLII mRNA | CTD | PMID:18445702 | piroxicam | multiple interactions | ISO | RGD:1316872 | 6480464 | [Piroxicam co-treated with Cisplatin] results in decreased expression of FLII mRNA | CTD | PMID:21858171 | selenium atom | increases expression | ISO | RGD:1316872 | 6480464 | Selenium results in increased expression of FLII mRNA | CTD | PMID:19244175 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of FLII protein | CTD | PMID:28918527 | sunitinib | increases expression | ISO | RGD:1316872 | 6480464 | Sunitinib results in increased expression of FLII mRNA | CTD | PMID:31533062 | tetraphene | multiple interactions | EXP | | 6480464 | [Benzoapyrene co-treated with benzaanthracene co-treated with benzobfluoranthene co-treated with chrysene] results in decreased expression of FLII mRNA | CTD | PMID:27858113 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of FLII protein | CTD | PMID:24648495 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of FLII mRNA | CTD | PMID:29264374 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of FLII mRNA | CTD | PMID:30912803 | valproic acid | decreases expression | ISO | RGD:1316872 | 6480464 | Valproic Acid results in decreased expression of FLII mRNA | CTD | PMID:29154799 | valproic acid | increases methylation | ISO | RGD:1316872 | 6480464 | Valproic Acid results in increased methylation of FLII gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | RGD:1316872 | 6480464 | Valproic Acid affects the expression of FLII mRNA | CTD | PMID:25979313 | vitamin E | increases expression | ISO | RGD:1316872 | 6480464 | Vitamin E results in increased expression of FLII mRNA | CTD | PMID:19244175 | |