Med15 (mediator complex subunit 15) - Rat Genome Database

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Gene: Med15 (mediator complex subunit 15) Mus musculus
Analyze
Symbol: Med15
Name: mediator complex subunit 15
RGD ID: 1316827
MGI Page MGI
Description: Predicted to enable transcription coregulator activity. Acts upstream of or within somatic stem cell population maintenance. Predicted to be located in nucleoplasm. Predicted to be part of core mediator complex. Is expressed in several structures, including branchial arch; central nervous system; facial prominence; limb; and limb bud. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MED15 (mediator complex subunit 15).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A230074L19Rik; AW536074; mediator of RNA polymerase II transcription subunit 15; mPcqap; Pc; PC2 glutamine/Q-rich-associated protein; Pcqap; positive cofactor 2 glutamine/Q-rich-associated protein; positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,469,072 - 17,540,811 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,469,072 - 17,550,755 (-)EnsemblGRCm39 Ensembl
GRCm381617,651,208 - 17,722,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,651,208 - 17,732,891 (-)EnsemblGRCm38mm10GRCm38
MGSCv371617,651,314 - 17,723,023 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361617,564,785 - 17,611,257 (-)NCBIMGSCv36mm8
Celera1618,224,459 - 18,296,014 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Association study between CAG trinucleotide repeats in the PCQAP gene (PC2 glutamine/Q-rich-associated protein) and schizophrenia. De Luca A, etal., Am J Med Genet B Neuropsychiatr Genet 2003 Jan 1;116(1):32-5.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. The Mediator complex and transcription regulation. Poss ZC, etal., Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11414760   PMID:11559591   PMID:12466851   PMID:12477932   PMID:12520002   PMID:14610273  
PMID:14614146   PMID:14681479   PMID:15449545   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18799693   PMID:20059953   PMID:20362541   PMID:20508642   PMID:20720539   PMID:21267068  
PMID:21677750   PMID:21873635   PMID:22496869   PMID:22922362   PMID:30196744   PMID:32325033   PMID:34161765   PMID:34506481   PMID:36878279  


Genomics

Comparative Map Data
Med15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,469,072 - 17,540,811 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,469,072 - 17,550,755 (-)EnsemblGRCm39 Ensembl
GRCm381617,651,208 - 17,722,947 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,651,208 - 17,732,891 (-)EnsemblGRCm38mm10GRCm38
MGSCv371617,651,314 - 17,723,023 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361617,564,785 - 17,611,257 (-)NCBIMGSCv36mm8
Celera1618,224,459 - 18,296,014 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.94NCBI
MED15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,507,610 - 20,587,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2220,495,913 - 20,587,632 (+)EnsemblGRCh38hg38GRCh38
GRCh372220,861,897 - 20,941,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,191,886 - 19,271,919 (+)NCBINCBI36Build 36hg18NCBI36
Build 342219,186,439 - 19,266,472NCBI
Celera224,352,845 - 4,432,848 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef224,129,649 - 4,209,632 (+)NCBIHuRef
CHM1_12220,862,630 - 20,942,640 (+)NCBICHM1_1
T2T-CHM13v2.02220,916,219 - 20,996,263 (+)NCBIT2T-CHM13v2.0
Med15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,784,974 - 96,859,635 (+)NCBIGRCr8
mRatBN7.21183,280,722 - 83,356,006 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,280,762 - 83,355,362 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1192,008,658 - 92,082,830 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,669,811 - 84,743,990 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,723,426 - 83,797,605 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,553,868 - 87,628,631 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,553,868 - 87,628,502 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,606,469 - 90,681,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,270,503 - 85,344,999 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11185,299,560 - 85,384,726 (+)NCBI
Celera1182,052,699 - 82,127,011 (+)NCBICelera
Cytogenetic Map11q23NCBI
Med15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544219,112,270 - 19,179,742 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544219,112,269 - 19,179,742 (+)NCBIChiLan1.0ChiLan1.0
MED15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22330,116,981 - 30,210,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12232,664,022 - 32,757,053 (+)NCBINHGRI_mPanPan1
PanPan1.12219,191,880 - 19,272,884 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2219,192,156 - 19,271,965 (+)Ensemblpanpan1.1panPan2
MED15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,299,424 - 30,368,460 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,299,442 - 30,367,572 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2630,258,317 - 30,327,156 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02631,707,993 - 31,776,853 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,707,980 - 31,776,849 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,753,891 - 29,822,740 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02629,378,095 - 29,446,935 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02630,467,664 - 30,536,521 (+)NCBIUU_Cfam_GSD_1.0
Med15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,973,141 - 140,067,071 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366192,687,011 - 2,759,294 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366192,687,004 - 2,780,898 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,703,019 - 50,759,310 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,703,010 - 50,759,310 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,266,459 - 54,318,847 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MED15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1195,111,512 - 5,195,677 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl195,112,435 - 5,167,139 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660851,741,216 - 1,826,089 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Med15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624945488,396 - 562,084 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Med15
1651 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:879
Count of miRNA genes:373
Interacting mature miRNAs:414
Transcripts:ENSMUST00000012259, ENSMUST00000080936
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120780888Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122500574Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122520318Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16713690629225471Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
15092082Igly9_mIgG glycosylation 9, GP17b (mouse)161477522320103513Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse

Markers in Region
AW536074  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381617,651,446 - 17,651,572UniSTSGRCm38
MGSCv371617,651,539 - 17,651,665UniSTSGRCm37
Celera1618,224,684 - 18,224,810UniSTS
Cytogenetic Map16A3UniSTS
cM Map169.9UniSTS
Whitehead/MRC_RH16135.12UniSTS
Pcqap  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381617,652,071 - 17,653,334UniSTSGRCm38
MGSCv371617,652,164 - 17,653,427UniSTSGRCm37
Celera1618,225,309 - 18,226,572UniSTS
Cytogenetic Map16A3UniSTS
cM Map169.9UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001040683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001285884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001285886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_033609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004939258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC087802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC115733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF328770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY201797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000012259   ⟹   ENSMUSP00000012259
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,469,075 - 17,540,811 (-)Ensembl
GRCm38.p6 Ensembl1617,651,211 - 17,722,947 (-)Ensembl
RefSeq Acc Id: ENSMUST00000080936   ⟹   ENSMUSP00000079737
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,469,085 - 17,540,761 (-)Ensembl
GRCm38.p6 Ensembl1617,651,221 - 17,722,897 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231231
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,473,072 - 17,473,717 (-)Ensembl
GRCm38.p6 Ensembl1617,655,208 - 17,655,853 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231413   ⟹   ENSMUSP00000156107
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,498,554 - 17,550,755 (-)Ensembl
GRCm38.p6 Ensembl1617,680,690 - 17,732,891 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231480
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,469,644 - 17,470,919 (-)Ensembl
GRCm38.p6 Ensembl1617,651,780 - 17,653,055 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231494
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,520,494 - 17,540,760 (-)Ensembl
GRCm38.p6 Ensembl1617,702,630 - 17,722,896 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231674   ⟹   ENSMUSP00000156305
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,473,134 - 17,540,772 (-)Ensembl
GRCm38.p6 Ensembl1617,655,270 - 17,722,908 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231754
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,514,636 - 17,540,776 (-)Ensembl
GRCm38.p6 Ensembl1617,696,772 - 17,722,912 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232005
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,495,831 - 17,540,772 (-)Ensembl
GRCm38.p6 Ensembl1617,677,967 - 17,722,908 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232012
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,470,780 - 17,471,585 (-)Ensembl
GRCm38.p6 Ensembl1617,652,916 - 17,653,721 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232163   ⟹   ENSMUSP00000155915
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,491,069 - 17,540,685 (-)Ensembl
GRCm38.p6 Ensembl1617,673,205 - 17,722,821 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232202   ⟹   ENSMUSP00000156139
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,490,933 - 17,540,744 (-)Ensembl
GRCm38.p6 Ensembl1617,673,069 - 17,722,880 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232236   ⟹   ENSMUSP00000156291
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,469,085 - 17,540,811 (-)Ensembl
GRCm38.p6 Ensembl1617,651,221 - 17,722,947 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232312
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,520,705 - 17,540,779 (-)Ensembl
GRCm38.p6 Ensembl1617,702,841 - 17,722,915 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232401
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,500,139 - 17,540,776 (-)Ensembl
GRCm38.p6 Ensembl1617,682,275 - 17,722,912 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232431   ⟹   ENSMUSP00000156371
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,498,524 - 17,540,771 (-)Ensembl
GRCm38.p6 Ensembl1617,680,660 - 17,722,907 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232645   ⟹   ENSMUSP00000156242
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,469,072 - 17,540,764 (-)Ensembl
GRCm38.p6 Ensembl1617,651,208 - 17,722,900 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232667
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,500,139 - 17,540,754 (-)Ensembl
GRCm38.p6 Ensembl1617,682,275 - 17,722,890 (-)Ensembl
RefSeq Acc Id: NM_001040683   ⟹   NP_001035773
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,072 - 17,540,811 (-)NCBI
GRCm381617,651,208 - 17,722,947 (-)NCBI
MGSCv371617,651,314 - 17,723,023 (-)RGD
Celera1618,224,446 - 18,296,031 (-)NCBI
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001285884   ⟹   NP_001272813
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,072 - 17,540,811 (-)NCBI
GRCm381617,651,208 - 17,722,947 (-)NCBI
Celera1618,224,446 - 18,296,031 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001285886   ⟹   NP_001272815
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,072 - 17,540,764 (-)NCBI
GRCm381617,651,208 - 17,722,900 (-)NCBI
Celera1618,224,446 - 18,296,031 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001358404   ⟹   NP_001345333
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,072 - 17,540,811 (-)NCBI
GRCm381617,651,208 - 17,722,947 (-)NCBI
Sequence:
RefSeq Acc Id: NM_033609   ⟹   NP_291087
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,072 - 17,540,811 (-)NCBI
GRCm381617,651,208 - 17,722,947 (-)NCBI
MGSCv371617,651,314 - 17,723,023 (-)RGD
Celera1618,224,446 - 18,296,031 (-)NCBI
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006522779   ⟹   XP_006522842
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,796 (-)NCBI
GRCm381617,651,211 - 17,722,930 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006522783   ⟹   XP_006522846
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,800 (-)NCBI
GRCm381617,651,211 - 17,722,933 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017317172   ⟹   XP_017172661
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,798 (-)NCBI
GRCm381617,651,211 - 17,722,933 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017317173   ⟹   XP_017172662
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,811 (-)NCBI
GRCm381617,651,211 - 17,722,947 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017317174   ⟹   XP_017172663
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,811 (-)NCBI
GRCm381617,651,211 - 17,722,947 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017317175   ⟹   XP_017172664
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,798 (-)NCBI
GRCm381617,651,211 - 17,722,933 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249346   ⟹   XP_030105206
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,521,278 (-)NCBI
GRCm381617,651,211 - 17,703,166 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249348   ⟹   XP_030105208
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,521,276 (-)NCBI
GRCm381617,651,211 - 17,703,166 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249349   ⟹   XP_030105209
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,795 (-)NCBI
GRCm381617,651,211 - 17,722,929 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249350   ⟹   XP_030105210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,796 (-)NCBI
GRCm381617,651,211 - 17,722,912 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160194   ⟹   XP_036016087
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,797 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160195   ⟹   XP_036016088
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,795 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160196   ⟹   XP_036016089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,521,013 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160197   ⟹   XP_036016090
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,795 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036160198   ⟹   XP_036016091
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,469,075 - 17,540,796 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004939258
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,473,019 - 17,540,811 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001035773 (Get FASTA)   NCBI Sequence Viewer  
  NP_001272813 (Get FASTA)   NCBI Sequence Viewer  
  NP_001272815 (Get FASTA)   NCBI Sequence Viewer  
  NP_001345333 (Get FASTA)   NCBI Sequence Viewer  
  NP_291087 (Get FASTA)   NCBI Sequence Viewer  
  XP_006522842 (Get FASTA)   NCBI Sequence Viewer  
  XP_006522846 (Get FASTA)   NCBI Sequence Viewer  
  XP_017172661 (Get FASTA)   NCBI Sequence Viewer  
  XP_017172662 (Get FASTA)   NCBI Sequence Viewer  
  XP_017172663 (Get FASTA)   NCBI Sequence Viewer  
  XP_017172664 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105206 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105208 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105209 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105210 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016087 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016088 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016089 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016090 (Get FASTA)   NCBI Sequence Viewer  
  XP_036016091 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH03221 (Get FASTA)   NCBI Sequence Viewer  
  AAH49891 (Get FASTA)   NCBI Sequence Viewer  
  AAH54779 (Get FASTA)   NCBI Sequence Viewer  
  AAK58424 (Get FASTA)   NCBI Sequence Viewer  
  BAD21436 (Get FASTA)   NCBI Sequence Viewer  
  BAE38826 (Get FASTA)   NCBI Sequence Viewer  
  BAE41448 (Get FASTA)   NCBI Sequence Viewer  
  EDK97476 (Get FASTA)   NCBI Sequence Viewer  
  EDK97477 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000012259
  ENSMUSP00000012259.8
  ENSMUSP00000079737
  ENSMUSP00000079737.7
  ENSMUSP00000155915.2
  ENSMUSP00000156107.2
  ENSMUSP00000156139.2
  ENSMUSP00000156242
  ENSMUSP00000156242.2
  ENSMUSP00000156291
  ENSMUSP00000156291.2
  ENSMUSP00000156305.2
  ENSMUSP00000156371.2
GenBank Protein Q924H2 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001035773   ⟸   NM_001040683
- Peptide Label: isoform b
- UniProtKB: E9Q7C1 (UniProtKB/TrEMBL),   Q6KAM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_291087   ⟸   NM_033609
- Peptide Label: isoform a
- UniProtKB: G3X8S4 (UniProtKB/Swiss-Prot),   Q924H2 (UniProtKB/Swiss-Prot),   Q6KAM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001272813   ⟸   NM_001285884
- Peptide Label: isoform c
- UniProtKB: Q3TE00 (UniProtKB/TrEMBL),   Q6KAM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001272815   ⟸   NM_001285886
- Peptide Label: isoform d
- UniProtKB: A0A338P730 (UniProtKB/TrEMBL),   Q3TLG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522846   ⟸   XM_006522783
- Peptide Label: isoform X11
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522842   ⟸   XM_006522779
- Peptide Label: isoform X3
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172663   ⟸   XM_017317174
- Peptide Label: isoform X7
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172662   ⟸   XM_017317173
- Peptide Label: isoform X4
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172661   ⟸   XM_017317172
- Peptide Label: isoform X2
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172664   ⟸   XM_017317175
- Peptide Label: isoform X13
- UniProtKB: Q3TLG6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345333   ⟸   NM_001358404
- Peptide Label: isoform e
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030105209   ⟸   XM_030249349
- Peptide Label: isoform X9
- UniProtKB: Q3TLG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030105210   ⟸   XM_030249350
- Peptide Label: isoform X10
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030105208   ⟸   XM_030249348
- Peptide Label: isoform X5
- UniProtKB: Q3TLG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030105206   ⟸   XM_030249346
- Peptide Label: isoform X1
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000012259   ⟸   ENSMUST00000012259
RefSeq Acc Id: ENSMUSP00000156305   ⟸   ENSMUST00000231674
RefSeq Acc Id: ENSMUSP00000156107   ⟸   ENSMUST00000231413
RefSeq Acc Id: ENSMUSP00000156291   ⟸   ENSMUST00000232236
RefSeq Acc Id: ENSMUSP00000156139   ⟸   ENSMUST00000232202
RefSeq Acc Id: ENSMUSP00000155915   ⟸   ENSMUST00000232163
RefSeq Acc Id: ENSMUSP00000156371   ⟸   ENSMUST00000232431
RefSeq Acc Id: ENSMUSP00000079737   ⟸   ENSMUST00000080936
RefSeq Acc Id: ENSMUSP00000156242   ⟸   ENSMUST00000232645
RefSeq Acc Id: XP_036016087   ⟸   XM_036160194
- Peptide Label: isoform X6
- UniProtKB: Q80UN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016091   ⟸   XM_036160198
- Peptide Label: isoform X14
- UniProtKB: Q80UN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016088   ⟸   XM_036160195
- Peptide Label: isoform X6
- UniProtKB: Q80UN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016090   ⟸   XM_036160197
- Peptide Label: isoform X12
- UniProtKB: Q3TLG6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036016089   ⟸   XM_036160196
- Peptide Label: isoform X8
- UniProtKB: Q6KAM1 (UniProtKB/TrEMBL)
Protein Domains
ARC105/Med15 mediator subunit C-terminal   ARC105/Med15 mediator subunit central   Mediator of RNA polymerase II transcription subunit

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q924H2-F1-model_v2 AlphaFold Q924H2 1-789 view protein structure

Promoters
RGD ID:6847316
Promoter ID:MM_ACW:19986
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour
Transcripts:MED15.ISEP07,   MED15.VASEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361617,655,596 - 17,656,096 (-)MPROMDB
RGD ID:6827255
Promoter ID:MM_KWN:20329
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000100120,   NM_001040683,   NM_033609,   UC007YLU.1,   UC007YLV.1,   UC007YLW.1,   UC007YLX.1,   UC007YLY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361617,722,556 - 17,723,056 (-)MPROMDB
RGD ID:8685628
Promoter ID:EPDNEW_M20845
Type:initiation region
Name:Med15_1
Description:Mus musculus mediator complex subunit 15 , transcript variant5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381617,722,896 - 17,722,956EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2137379 AgrOrtholog
Ensembl Genes ENSMUSG00000012114 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000012259 ENTREZGENE
  ENSMUST00000012259.9 UniProtKB/Swiss-Prot
  ENSMUST00000080936 ENTREZGENE
  ENSMUST00000080936.14 UniProtKB/TrEMBL
  ENSMUST00000231413.2 UniProtKB/TrEMBL
  ENSMUST00000231674.2 UniProtKB/TrEMBL
  ENSMUST00000232163.2 UniProtKB/TrEMBL
  ENSMUST00000232202.2 UniProtKB/TrEMBL
  ENSMUST00000232236 ENTREZGENE
  ENSMUST00000232236.2 UniProtKB/TrEMBL
  ENSMUST00000232431.2 UniProtKB/TrEMBL
  ENSMUST00000232645 ENTREZGENE
  ENSMUST00000232645.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.246.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro KIX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Med15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Med15_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Med15_central UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:94112 UniProtKB/Swiss-Prot
MGD MGI:2137379 ENTREZGENE
NCBI Gene 94112 ENTREZGENE
PANTHER MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 UniProtKB/Swiss-Prot
  MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 UniProtKB/Swiss-Prot
  MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 UniProtKB/TrEMBL
  MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 UniProtKB/TrEMBL
Pfam Med15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Med15_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Med15_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Med15 PhenoGen
UniProt A0A338P6A9_MOUSE UniProtKB/TrEMBL
  A0A338P6U0_MOUSE UniProtKB/TrEMBL
  A0A338P6V8_MOUSE UniProtKB/TrEMBL
  A0A338P730 ENTREZGENE, UniProtKB/TrEMBL
  A0A338P7C4_MOUSE UniProtKB/TrEMBL
  A0A338P7G2_MOUSE UniProtKB/TrEMBL
  A0JLM5_MOUSE UniProtKB/TrEMBL
  E9Q7C1 ENTREZGENE, UniProtKB/TrEMBL
  G3X8S4 ENTREZGENE
  MED15_MOUSE UniProtKB/Swiss-Prot
  Q3TE00 ENTREZGENE, UniProtKB/TrEMBL
  Q3TLG6 ENTREZGENE, UniProtKB/TrEMBL
  Q6KAM1 ENTREZGENE, UniProtKB/TrEMBL
  Q7TQE1_MOUSE UniProtKB/TrEMBL
  Q80UN2 ENTREZGENE, UniProtKB/TrEMBL
  Q924H2 ENTREZGENE
UniProt Secondary G3X8S4 UniProtKB/Swiss-Prot