Fech (ferrochelatase) - Rat Genome Database

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Gene: Fech (ferrochelatase) Mus musculus
Analyze
Symbol: Fech
Name: ferrochelatase
RGD ID: 1316820
MGI Page MGI
Description: Enables several functions, including ferrochelatase activity; heme binding activity; and iron-responsive element binding activity. Acts upstream of or within several processes, including porphyrin-containing compound metabolic process; regulation of cellular macromolecule biosynthetic process; and very-low-density lipoprotein particle assembly. Located in mitochondrial inner membrane. Is expressed in several structures, including choroid plexus; heart; integumental system; liver and biliary system; and respiratory system. Used to study erythropoietic protoporphyria. Human ortholog(s) of this gene implicated in cutaneous porphyria and erythropoietic protoporphyria. Orthologous to human FECH (ferrochelatase).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI894116; Fc; fch; Fcl; ferrochelatase, mitochondrial; heme synthase; heme synthetase; protoheme ferro-lyase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391864,589,613 - 64,622,169 (-)NCBIGRCm39mm39
GRCm39 Ensembl1864,585,985 - 64,623,322 (-)Ensembl
GRCm381864,456,542 - 64,489,098 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1864,452,914 - 64,490,251 (-)EnsemblGRCm38mm10GRCm38
MGSCv371864,616,204 - 64,648,720 (-)NCBIGRCm37mm9NCBIm37
MGSCv361864,581,919 - 64,614,435 (-)NCBImm8
Celera1865,723,518 - 65,755,460 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1837.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(E)-cinnamyl alcohol  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine  (EXP)
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aminolevulinic acid  (EXP)
acetamide  (ISO)
acrylamide  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
antirheumatic drug  (ISO)
atrazine  (ISO)
Bandrowski's base  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzoic acid  (ISO)
bisphenol A  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
chloroacetaldehyde  (ISO)
chlorpromazine  (ISO)
choline  (EXP)
cidofovir anhydrous  (ISO)
cinnamyl alcohol  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
desferrioxamine B  (ISO)
diazinon  (ISO)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (EXP)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
eugenol  (ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
glafenine  (ISO)
griseofulvin  (EXP)
hexane  (ISO)
hydrogen peroxide  (ISO)
ifosfamide  (ISO)
iron atom  (EXP,ISO)
iron trichloride  (ISO)
iron(0)  (EXP,ISO)
isoeugenol  (ISO)
isoniazide  (EXP,ISO)
L-methionine  (EXP)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methyl salicylate  (ISO)
N-ethyl-N-nitrosourea  (EXP)
nefazodone  (ISO)
nickel sulfate  (ISO)
nimesulide  (ISO)
nitrofen  (ISO)
ochratoxin A  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
porphobilinogen  (EXP)
propan-2-ol  (ISO)
protoporphyrin  (EXP)
rac-lactic acid  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tauro-beta-muricholic acid  (EXP)
taurochenodeoxycholic acid  (EXP)
taurocholic acid  (EXP)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
trans-isoeugenol  (ISO)
tributylstannane  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
mitochondrial inner membrane  (IDA,TAS)
mitochondrion  (HDA,IBA,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:1704134   PMID:1939658   PMID:2246229   PMID:4596202   PMID:7567998   PMID:7575558   PMID:7592570   PMID:8276824   PMID:8325637   PMID:8611576   PMID:8973195   PMID:9989256  
PMID:10023040   PMID:10349636   PMID:10582332   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11160364   PMID:11215517   PMID:11544199   PMID:12081474   PMID:12149233   PMID:12477932  
PMID:12533832   PMID:14610273   PMID:14651853   PMID:14681479   PMID:14981080   PMID:15496139   PMID:15660916   PMID:15677551   PMID:15747579   PMID:15782199   PMID:15793285   PMID:15923635  
PMID:15931390   PMID:16141072   PMID:16141073   PMID:16306232   PMID:16503645   PMID:16792525   PMID:16859999   PMID:17003376   PMID:17600043   PMID:18044970   PMID:18423489   PMID:18593702  
PMID:18614015   PMID:18780836   PMID:19251765   PMID:19543923   PMID:19657351   PMID:19691493   PMID:19965627   PMID:20427704   PMID:20508144   PMID:20966079   PMID:21222436   PMID:21267068  
PMID:21873635   PMID:21903580   PMID:23395172   PMID:24421385   PMID:25414439   PMID:26287972   PMID:26465331   PMID:26551679   PMID:27507172   PMID:27599036   PMID:28093505   PMID:28377496  
PMID:30366982   PMID:30765471   PMID:31555729   PMID:32716567   PMID:32968282   PMID:33620374  


Genomics

Comparative Map Data
Fech
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391864,589,613 - 64,622,169 (-)NCBIGRCm39mm39
GRCm39 Ensembl1864,585,985 - 64,623,322 (-)Ensembl
GRCm381864,456,542 - 64,489,098 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1864,452,914 - 64,490,251 (-)EnsemblGRCm38mm10GRCm38
MGSCv371864,616,204 - 64,648,720 (-)NCBIGRCm37mm9NCBIm37
MGSCv361864,581,919 - 64,614,435 (-)NCBImm8
Celera1865,723,518 - 65,755,460 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1837.43NCBI
FECH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1857,544,377 - 57,586,732 (-)EnsemblGRCh38hg38GRCh38
GRCh381857,544,377 - 57,586,708 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371855,211,609 - 55,253,934 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361853,366,535 - 53,404,988 (-)NCBINCBI36hg18NCBI36
Build 341853,366,534 - 53,404,988NCBI
Celera1851,928,883 - 51,970,808 (-)NCBI
Cytogenetic Map18q21.31NCBI
HuRef1851,922,248 - 51,964,183 (-)NCBIHuRef
CHM1_11855,207,292 - 55,249,187 (-)NCBICHM1_1
Fech
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21857,945,123 - 57,978,327 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1857,945,122 - 57,979,348 (-)Ensembl
Rnor_6.01859,941,992 - 59,975,192 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1859,941,992 - 59,975,192 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01859,152,151 - 59,185,351 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41860,675,217 - 60,708,418 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11860,748,886 - 60,781,609 (-)NCBI
Celera1856,082,277 - 56,115,455 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
Fech
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540241,902,868 - 41,938,174 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540241,902,868 - 41,938,099 (-)NCBIChiLan1.0ChiLan1.0
FECH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11854,273,527 - 54,312,255 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1854,273,527 - 54,312,378 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01850,934,520 - 50,977,132 (-)NCBIMhudiblu_PPA_v0panPan3
FECH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1118,352,184 - 18,384,251 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl118,345,811 - 18,383,092 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha119,330,379 - 19,366,324 (+)NCBI
ROS_Cfam_1.0118,227,872 - 18,263,839 (+)NCBI
ROS_Cfam_1.0 Ensembl118,227,773 - 18,265,197 (+)Ensembl
UMICH_Zoey_3.1118,284,504 - 18,320,457 (+)NCBI
UNSW_CanFamBas_1.0118,182,273 - 18,218,239 (+)NCBI
UU_Cfam_GSD_1.0118,451,188 - 18,487,178 (+)NCBI
Fech
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494431,516,610 - 31,549,529 (+)NCBI
SpeTri2.0NW_0049364976,755,626 - 6,788,568 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FECH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1106,854,002 - 106,898,418 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11106,861,628 - 106,898,407 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21117,466,662 - 117,487,827 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FECH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11822,143,268 - 22,182,259 (+)NCBIChlSab1.1chlSab2
ChlSab1.11822,143,268 - 22,182,259 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1822,143,483 - 22,182,416 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660603,386,537 - 3,424,620 (-)NCBIVero_WHO_p1.0
Fech
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247923,067,270 - 3,101,698 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AI894116  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381864,457,424 - 64,457,505UniSTSGRCm38
MGSCv371864,617,078 - 64,617,159UniSTSGRCm37
Celera1865,724,392 - 65,724,473UniSTS
Cytogenetic Map18E1UniSTS
cM Map1839.0UniSTS
Whitehead/MRC_RH18827.62UniSTS
M61215  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381864,457,767 - 64,457,948UniSTSGRCm38
MGSCv371864,617,421 - 64,617,602UniSTSGRCm37
Celera1865,724,735 - 65,724,916UniSTS
Cytogenetic Map18E1UniSTS
cM Map1839.0UniSTS
Whitehead/MRC_RH18827.52UniSTS
Whitehead_YAC18 UniSTS
MHAa30f10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381864,487,493 - 64,487,615UniSTSGRCm38
MGSCv371864,647,147 - 64,647,269UniSTSGRCm37
Celera1865,753,887 - 65,754,009UniSTS
Cytogenetic Map18E1UniSTS
cM Map1839.0UniSTS
Whitehead_YAC18 UniSTS
D18Mit206  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381864,458,775 - 64,458,894UniSTSGRCm38
MGSCv371864,618,429 - 64,618,548UniSTSGRCm37
Celera1865,725,743 - 65,725,864UniSTS
Cytogenetic Map18E1UniSTS
cM Map1837.0UniSTS
Whitehead Genetic1825.1UniSTS
Whitehead/MRC_RH18827.62UniSTS
Whitehead_YAC18 UniSTS
M61215  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381864,457,929 - 64,458,014UniSTSGRCm38
MGSCv371864,617,583 - 64,617,668UniSTSGRCm37
Celera1865,724,897 - 65,724,982UniSTS
Cytogenetic Map18E1UniSTS
Whitehead/MRC_RH18827.52UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181389696666965891Mouse
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182476282478296340Mouse
1300685Scc5_mcolon tumor susceptibility 5 (mouse)Not determined183185541365855562Mouse
1357690Vtbt19_mvertebral trabecular bone trait 19 (mouse)Not determined183295797666958154Mouse
1301771Pcyts6_mplasmacytoma susceptibility 6 (mouse)Not determined183552556069525779Mouse
4142366Chlq10_mcirculating hormone level QTL 10 (mouse)Not determined183615795070158108Mouse
15039381Ltgq8_mliver triglyceride QTL 8 (mouse)183807349772073497Mouse
15039383Mvlq5_mmicrovesicular liver lesion QTL 5 (mouse)183807349772073497Mouse
15039384Liviq1_mliver inflammation QTL 1 (mouse)183807349772073497Mouse
15039386Mvlq4_mmacrovesicular liver lesion QTL 4 (mouse)183807349772073497Mouse
12050070Nabq2_mnasal bone morphology QTL 2 (mouse)183897060572970721Mouse
1357639Obsty4_mobesity 4 (mouse)Not determined183948686184620653Mouse
1301902Hrtfm4_mheart failure modifier 4 (mouse)Not determined184317804877178271Mouse
1301215Thcr_mT helper cell response (mouse)Not determined184499753768645706Mouse
12904745Carcdq2_mcardiac collagen deposition QTL 2 (mouse)184629021680290216Mouse
11039493Ltpr8d_mLeishmania tropica response 8d (mouse)184674183280741971Mouse
11039494Ltpr8b_mLeishmania tropica response 8b (mouse)184674183280741971Mouse
1357630Tgq1_mtriglyceride QTL 1 (mouse)Not determined185091908584919240Mouse
11252137Modvl5_mmodifier of vacuolated lens 5 (mouse)185091908584919240Mouse
1302099Hdlq30_mHDL QTL 30 (mouse)Not determined185153522985535397Mouse
10412244Par5_mpulmonary adenoma resistance 5 (mouse)Not determined185153522985535397Mouse
1301853Heal9_mwound healing/regeneration 9 (mouse)Not determined185267220586672345Mouse
1302050Radpf4_mradiation pulmonary fibrosis 4 (mouse)Not determined185283308468645706Mouse
4142443Pgis1_mproteoglycan induced spondylitis 1 (mouse)Not determined185315795076826598Mouse
1301500Szs4_mseizure susceptibility 4 (mouse)Not determined185484280185496018Mouse
12880410V125Dq13_mvitamin D active form serum level QTL 13 (mouse)185630000090300000Mouse
12880430Fgf23lq4_mFGF23 serum level QTL 4 (mouse)185630000090300000Mouse
10412183Sstapa2_mSuseptibility to Staphylococus aureus infection 2 (mouse)Not determined185666155866819414Mouse
12880428V125Dq14_mvitamin D active form serum level QTL 14 (mouse)185730000090702639Mouse
1301353Lbw6_mlupus NZB x NZW 6 (mouse)Not determined185742926790702639Mouse
4141132Eae18_mexperimental allergic encephalomyelitis susceptibility 18 (mouse)Not determined5745748782586603Mouse
4140971Mbmq1_mmale body mass QTL 1 (mouse)Not determined5785721090702639Mouse
12910791Pwgrq8_mpre-weaning growth rate QTL 8 (mouse)185788832769216071Mouse
11039492Ltpr8a_mLeishmania tropica response 8a (mouse)185904702190702639Mouse
11039495Ltpr8c_mLeishmania tropica response 8c (mouse)185904702190702639Mouse
11049564Lmr29_mleishmaniasis resistance 29 (mouse)185904702190702639Mouse
1301103Pgia11_mproteoglycan induced arthritis 11 (mouse)Not determined185982648990702639Mouse
1302109Sluc28_msusceptibility to lung cancer 28 (mouse)Not determined185984762690702639Mouse
38455998Cdtm1_mCD62L+ CD8 TM cells 1 (mouse)186000000080000000Mouse
10412265Par7_mpulmonary adenoma resistance 7 (mouse)Not determined186113937667919240Mouse
4142239Idd21.2_minsulin dependent diabetes susceptibility 21.2 (mouse)Not determined186113937674429343Mouse
1558803W3q16_mweight 3 weeks QTL 16 (mouse)Not determined186113937681448616Mouse
1558782Orgwq9_morgan weight QTL 9 (mouse)Not determined186113937682586603Mouse
11039518Ltpr8_mLeishmania tropica response 8 (mouse)186374183276047170Mouse
13824986Flal2_mfatty liver accumulation QTL 2, females only (mouse)186400000066000000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:505
Count of miRNA genes:333
Interacting mature miRNAs:371
Transcripts:ENSMUST00000025484
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001348055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036160984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_385974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB017808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC102106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC102268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02072539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02072540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP766542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY754052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M61215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000025484   ⟹   ENSMUSP00000025484
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,336 - 64,622,134 (-)Ensembl
GRCm38.p6 Ensembl1864,457,265 - 64,489,063 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235215   ⟹   ENSMUSP00000158210
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,333 - 64,622,122 (-)Ensembl
GRCm38.p6 Ensembl1864,457,262 - 64,489,051 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235338
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,612 - 64,612,582 (-)Ensembl
GRCm38.p6 Ensembl1864,457,541 - 64,479,511 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235356
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,603,072 - 64,605,281 (-)Ensembl
GRCm38.p6 Ensembl1864,470,001 - 64,472,210 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235766   ⟹   ENSMUSP00000157863
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,585,985 - 64,622,121 (-)Ensembl
GRCm38.p6 Ensembl1864,452,914 - 64,489,050 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235843
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,613,109 - 64,622,105 (-)Ensembl
GRCm38.p6 Ensembl1864,480,038 - 64,489,034 (-)Ensembl
RefSeq Acc Id: ENSMUST00000235947   ⟹   ENSMUSP00000158161
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,336 - 64,608,197 (-)Ensembl
GRCm38.p6 Ensembl1864,457,265 - 64,475,126 (-)Ensembl
RefSeq Acc Id: ENSMUST00000236586   ⟹   ENSMUSP00000157791
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,585,985 - 64,622,171 (-)Ensembl
GRCm38.p6 Ensembl1864,452,914 - 64,489,100 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237358   ⟹   ENSMUSP00000158038
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,793 - 64,623,322 (-)Ensembl
GRCm38.p6 Ensembl1864,457,722 - 64,490,251 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237502   ⟹   ENSMUSP00000157798
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,336 - 64,622,144 (-)Ensembl
GRCm38.p6 Ensembl1864,457,265 - 64,489,073 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237680   ⟹   ENSMUSP00000157946
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,611 - 64,622,055 (-)Ensembl
GRCm38.p6 Ensembl1864,457,540 - 64,488,984 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237717
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,332 - 64,612,486 (-)Ensembl
GRCm38.p6 Ensembl1864,457,261 - 64,479,415 (-)Ensembl
RefSeq Acc Id: ENSMUST00000237891   ⟹   ENSMUSP00000158505
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,600,847 - 64,622,501 (-)Ensembl
GRCm38.p6 Ensembl1864,467,776 - 64,489,430 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238082
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,590,965 - 64,597,397 (-)Ensembl
GRCm38.p6 Ensembl1864,457,894 - 64,464,326 (-)Ensembl
RefSeq Acc Id: ENSMUST00000238149   ⟹   ENSMUSP00000158387
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1864,608,218 - 64,622,012 (-)Ensembl
GRCm38.p6 Ensembl1864,475,147 - 64,488,941 (-)Ensembl
RefSeq Acc Id: NM_001348055   ⟹   NP_001334984
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391864,589,613 - 64,622,169 (-)NCBI
GRCm381864,456,542 - 64,489,098 (-)NCBI
Sequence:
RefSeq Acc Id: NM_007998   ⟹   NP_032024
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391864,589,613 - 64,622,169 (-)NCBI
GRCm381864,456,542 - 64,489,098 (-)NCBI
MGSCv371864,616,204 - 64,648,720 (-)RGD
Celera1865,723,518 - 65,755,460 (-)RGD
cM Map18 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036160984   ⟹   XP_036016877
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391864,589,613 - 64,622,036 (-)NCBI
Sequence:
RefSeq Acc Id: XR_385974
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391864,589,613 - 64,622,169 (-)NCBI
GRCm381864,456,542 - 64,489,081 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032024   ⟸   NM_007998
- Peptide Label: isoform 1
- UniProtKB: Q544X6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001334984   ⟸   NM_001348055
- Peptide Label: isoform 2
- UniProtKB: Q4QRK2 (UniProtKB/TrEMBL),   Q544X6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000158505   ⟸   ENSMUST00000237891
RefSeq Acc Id: ENSMUSP00000157798   ⟸   ENSMUST00000237502
RefSeq Acc Id: ENSMUSP00000158038   ⟸   ENSMUST00000237358
RefSeq Acc Id: ENSMUSP00000157946   ⟸   ENSMUST00000237680
RefSeq Acc Id: ENSMUSP00000157791   ⟸   ENSMUST00000236586
RefSeq Acc Id: ENSMUSP00000158387   ⟸   ENSMUST00000238149
RefSeq Acc Id: ENSMUSP00000157863   ⟸   ENSMUST00000235766
RefSeq Acc Id: ENSMUSP00000158161   ⟸   ENSMUST00000235947
RefSeq Acc Id: ENSMUSP00000025484   ⟸   ENSMUST00000025484
RefSeq Acc Id: ENSMUSP00000158210   ⟸   ENSMUST00000235215
RefSeq Acc Id: XP_036016877   ⟸   XM_036160984
- Peptide Label: isoform X1

Promoters
RGD ID:13678012
Promoter ID:EPDNEW_M23155
Type:multiple initiation site
Name:Fech_2
Description:Mus musculus ferrochelatase , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23156  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381864,488,955 - 64,489,015EPDNEW
RGD ID:13678014
Promoter ID:EPDNEW_M23156
Type:initiation region
Name:Fech_1
Description:Mus musculus ferrochelatase , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23155  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381864,489,068 - 64,489,128EPDNEW
RGD ID:6829233
Promoter ID:MM_KWN:25487
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000025484,   UC008FEI.1,   UC008FEJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361864,648,406 - 64,648,906 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95513 AgrOrtholog
Ensembl Genes ENSMUSG00000024588 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000025484 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000157791 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000157798 UniProtKB/TrEMBL
  ENSMUSP00000157863 UniProtKB/TrEMBL
  ENSMUSP00000157946 UniProtKB/TrEMBL
  ENSMUSP00000158038 UniProtKB/TrEMBL
  ENSMUSP00000158161 UniProtKB/TrEMBL
  ENSMUSP00000158210 UniProtKB/TrEMBL
  ENSMUSP00000158387 UniProtKB/TrEMBL
  ENSMUSP00000158505 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000025484 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000235215 UniProtKB/TrEMBL
  ENSMUST00000235766 UniProtKB/TrEMBL
  ENSMUST00000235947 UniProtKB/TrEMBL
  ENSMUST00000236586 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000237358 UniProtKB/TrEMBL
  ENSMUST00000237502 UniProtKB/TrEMBL
  ENSMUST00000237680 UniProtKB/TrEMBL
  ENSMUST00000237891 UniProtKB/TrEMBL
  ENSMUST00000238149 UniProtKB/TrEMBL
InterPro Ferrochelatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ferrochelatase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ferrochelatase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ferrochelatase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14151 UniProtKB/TrEMBL
MGD MGI:95513 ENTREZGENE
NCBI Gene 14151 ENTREZGENE
PANTHER PTHR11108 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ferrochelatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fech PhenoGen
PROSITE FERROCHELATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs hemH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494B9Y8_MOUSE UniProtKB/TrEMBL
  A0A494BA61_MOUSE UniProtKB/TrEMBL
  A0A494BAI5_MOUSE UniProtKB/TrEMBL
  A0A494BAR8_MOUSE UniProtKB/TrEMBL
  A0A494BAV9_MOUSE UniProtKB/TrEMBL
  A0A494BB70_MOUSE UniProtKB/TrEMBL
  A0A494BBL4_MOUSE UniProtKB/TrEMBL
  F6T2S0_MOUSE UniProtKB/TrEMBL
  HEMH_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UC49_MOUSE UniProtKB/TrEMBL
  Q4QRK2 ENTREZGENE, UniProtKB/TrEMBL
  Q544X6 ENTREZGENE, UniProtKB/TrEMBL
  Q8C3V7_MOUSE UniProtKB/TrEMBL
  Q91W09_MOUSE UniProtKB/TrEMBL