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Gene: Foxe3 (forkhead box E3) Mus musculus
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Symbol: Foxe3
Name: forkhead box E3
Description: Exhibits sequence-specific DNA binding activity. Involved in several processes, including camera-type eye development; negative regulation of lens fiber cell differentiation; and positive regulation of lens epithelial cell proliferation. Localizes to the nucleus. Used to study congenital aphakia. Human ortholog(s) of this gene implicated in anterior segment dysgenesis; cataract 34 multiple types; congenital aphakia; and thoracic aortic aneurysm. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; eye; and heart. Orthologous to human FOXE3 (forkhead box E3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dyl; dysgenetic lens; forkhead box protein E3; FREAC8; rct; Rinshoken cataract
Orthologs:
Homo sapiens (human) : FOXE3 (forkhead box E3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Foxe3 (forkhead box E3)  Alliance
Canis lupus familiaris (dog) : FOXE3 (forkhead box E3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxe3 (forkhead box E3)
Sus scrofa (pig) : FOXE3 (forkhead box E3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384114,924,443 - 114,926,067 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374114,597,752 - 114,598,618 (-)NCBIGRCm37mm9NCBIm37
MGSCv364114,423,079 - 114,423,945 (-)NCBImm8
Celera4113,672,921 - 113,673,787 (-)NCBICelera
Cytogenetic Map4 D1NCBI
cM Map452.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Foxe3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316816
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.