Pmel (premelanosome protein) - Rat Genome Database

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Gene: Pmel (premelanosome protein) Mus musculus
Analyze
Symbol: Pmel
Name: premelanosome protein
RGD ID: 1316752
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Involved in positive regulation of melanin biosynthetic process. Acts upstream of or within melanin biosynthetic process. Located in melanosome. Is expressed in several structures, including alimentary system; genitourinary system; mesenchyme derived from neural crest; nervous system; and sensory organ. Orthologous to human PMEL (premelanosome protein).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D10H12S53; D10H12S53E; D12S53E; D12S53Eh; gp10; gp100; gp8; gp87; melanocyte protein PMEL; melanocyte protein Pmel 17; Pmel17; Si; Silv; silver locus protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,531,757 - 128,555,993 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,540,064 - 128,556,107 (+)EnsemblGRCm39 Ensembl
GRCm3810128,695,888 - 128,720,238 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,704,195 - 128,720,238 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710128,143,314 - 128,157,294 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610128,109,207 - 128,123,073 (+)NCBIMGSCv36mm8
Celera10131,098,390 - 131,112,396 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
melanoma  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Experimental Data Annotations     Click to see Annotation Detail View

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. Disordered expression of the sucrase-isomaltase complex in the small intestine in Otsuka Long-Evans tokushima fatty rats, a model of non-insulin-dependent diabetes mellitus with insulin resistance. Adachi T, etal., Biochim Biophys Acta. 1999 Jan 4;1426(1):126-32.
2. Morphological changes and increased sucrase and isomaltase activity in small intestines of insulin-deficient and type 2 diabetic rats. Adachi T, etal., Endocr J. 2003 Jun;50(3):271-9.
3. Mucosal function in rat jejunum and ileum is altered by induction of colitis. Amit-Romach E, etal., Int J Mol Med. 2006 Oct;18(4):721-7.
4. Enhancement of brush border membrane peptidase activity in rat jejunum induced by starvation. Ihara T, etal., Pflugers Arch. 2000 May;440(1):75-83.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Expression of intestinal brush-border membrane hydrolases and ferritin after segmental ischemia-reperfusion in rats. Yeh KY, etal., Am J Physiol. 1998 Sep;275(3 Pt 1):G572-83.
Additional References at PubMed
PMID:1912584   PMID:1924386   PMID:7479744   PMID:7558008   PMID:7665913   PMID:7738386   PMID:7761347   PMID:7870580   PMID:7961886   PMID:8041749   PMID:8288218   PMID:8432998  
PMID:8570653   PMID:8592076   PMID:8617263   PMID:8617992   PMID:8739560   PMID:9101410   PMID:10349636   PMID:10594241   PMID:11042159   PMID:11076861   PMID:11092553   PMID:11266470  
PMID:11277491   PMID:12477932   PMID:14610273   PMID:14643677   PMID:14681479   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16185282   PMID:16332269   PMID:16412618   PMID:16760433  
PMID:18397875   PMID:18454205   PMID:18715234   PMID:18799693   PMID:19493314   PMID:19576202   PMID:19659570   PMID:19679373   PMID:21610032   PMID:21677750   PMID:21873635   PMID:21949658  
PMID:22706087   PMID:23203930   PMID:23333945   PMID:23382688   PMID:23754390   PMID:24218449   PMID:24650003   PMID:24769727   PMID:24875170   PMID:25633711   PMID:25792196   PMID:26732977  
PMID:26876013   PMID:27903862   PMID:28249010   PMID:28334846   PMID:28746871   PMID:30635393   PMID:34474245   PMID:34503492   PMID:34878101   PMID:36318272   PMID:37591247   PMID:38355793  


Genomics

Comparative Map Data
Pmel
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,531,757 - 128,555,993 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,540,064 - 128,556,107 (+)EnsemblGRCm39 Ensembl
GRCm3810128,695,888 - 128,720,238 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,704,195 - 128,720,238 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710128,143,314 - 128,157,294 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610128,109,207 - 128,123,073 (+)NCBIMGSCv36mm8
Celera10131,098,390 - 131,112,396 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.13NCBI
PMEL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381255,954,105 - 55,966,709 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1255,954,105 - 55,973,317 (-)EnsemblGRCh38hg38GRCh38
GRCh371256,347,889 - 56,360,493 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,634,156 - 54,646,093 (-)NCBINCBI36Build 36hg18NCBI36
Build 341254,634,156 - 54,646,093NCBI
Celera1256,000,543 - 56,012,534 (-)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1253,386,917 - 53,399,406 (-)NCBIHuRef
CHM1_11256,315,023 - 56,327,629 (-)NCBICHM1_1
T2T-CHM13v2.01255,921,167 - 55,933,772 (-)NCBIT2T-CHM13v2.0
Pmel
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,721,948 - 1,733,248 (+)NCBIGRCr8
mRatBN7.271,138,202 - 1,148,735 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl71,138,586 - 1,148,746 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.073,133,347 - 3,143,827 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl73,133,506 - 3,143,911 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.073,105,316 - 3,116,614 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.472,007,882 - 2,018,998 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.172,008,881 - 2,018,859 (+)NCBI
Celera71,008,541 - 1,019,007 (+)NCBICelera
Cytogenetic Map7q11NCBI
Pmel
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,544,961 - 3,554,619 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,544,855 - 3,555,453 (-)NCBIChiLan1.0ChiLan1.0
PMEL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,363,001 - 38,374,882 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,359,773 - 38,371,654 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,946,951 - 32,958,205 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,196,656 - 33,207,610 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,196,040 - 33,207,610 (+)Ensemblpanpan1.1panPan2
PMEL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110292,595 - 327,618 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10292,597 - 300,098 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10354,530 - 362,031 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010299,404 - 334,246 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10299,405 - 306,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110277,211 - 284,717 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010519,995 - 527,495 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010644,259 - 651,766 (-)NCBIUU_Cfam_GSD_1.0
Pmel
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,491,116 - 58,502,171 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646365,809 - 379,130 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646368,064 - 379,085 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PMEL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,355,619 - 21,364,987 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,355,611 - 21,365,609 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PMEL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11151,892,131 - 51,905,073 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1151,887,730 - 51,904,324 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037194,082,197 - 194,095,017 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pmel
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480212,083,090 - 12,092,767 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480212,073,932 - 12,092,885 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pmel
566 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:80
Interacting mature miRNAs:85
Transcripts:ENSMUST00000054125
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097217101130530862Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10100986516130530862Mouse
12904000Opfaq7_mopen field activity QTL 7 (mouse)10127746318129466375Mouse
12904001Opfaq10_mopen field activity QTL 10 (mouse)10125633671129466375Mouse
12879490Frct3_mfear conditioning traits 3 (mouse)10122785970129466996Mouse
11049570Lmr25b_mleishmaniasis resistance 25b (mouse)10108575094130530862Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101497164130530862Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097217101130530862Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104110021130530862Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10102847852130530862Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105041304130530862Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102506908130530862Mouse
14746996Manh69_mmandible shape 69 (mouse)10104763638130530862Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097535905130530862Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101497164130530862Mouse
4141153Ltgq2_mliver triglyceride QTL 2 (mouse)Not determined108515907130530862Mouse
11039496Ltpr5b_mLeishmania tropica response 5b (mouse)10108575094130530862Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10100986516130530862Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97758644130530862Mouse
11041664Lmr25_mleishmaniasis resistance 25 (mouse)10108575094130530862Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105041304130530862Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103243727130530862Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397217101130530862Mouse
12911221Frct3d_mfear conditioning traits 3d (mouse)10127675574129466996Mouse
12911220Frct3c_mfear conditioning traits 3c (mouse)10122785970129466996Mouse
11049563Lmr25a_mleishmaniasis resistance 25a (mouse)10108575094130530862Mouse
4142089Obrq9_mobesity resistance QTL 9 (mouse)Not determined108515907130530862Mouse
12911219Frct3b_mfear conditioning traits 3b (mouse)10127675574129466996Mouse
12911218Frct3a_mfear conditioning traits 3a (mouse)10122785970129466996Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10102902508130530862Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099220635130530862Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105179713130530862Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099220635130530862Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097217101130530862Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105179713130530862Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099220635130530862Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105041304130530862Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105179713130530862Mouse

Markers in Region
AW146112  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3810128,720,397 - 128,720,496UniSTSGRCm38
MGSCv3710128,157,453 - 128,157,552UniSTSGRCm37
Celera10131,112,555 - 131,112,654UniSTS
Cytogenetic Map10D3UniSTS
cM Map1071.0UniSTS
cM Map1070.0UniSTS
Whitehead/MRC_RH101377.27UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_021882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030244967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036155712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC117232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC138108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF118450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF119092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC075667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ541090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MH882516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U14133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000054125   ⟹   ENSMUSP00000051869
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10128,542,127 - 128,556,107 (+)Ensembl
GRCm38.p6 Ensembl10128,706,258 - 128,720,238 (+)Ensembl
Ensembl Acc Id: ENSMUST00000217836   ⟹   ENSMUSP00000151602
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10128,540,064 - 128,551,496 (+)Ensembl
GRCm38.p6 Ensembl10128,704,195 - 128,715,627 (+)Ensembl
Ensembl Acc Id: ENSMUST00000219157   ⟹   ENSMUSP00000151621
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10128,541,049 - 128,551,225 (+)Ensembl
GRCm38.p6 Ensembl10128,705,180 - 128,715,356 (+)Ensembl
RefSeq Acc Id: NM_021882   ⟹   NP_068682
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910128,542,127 - 128,555,993 (+)NCBI
GRCm3810128,706,258 - 128,720,238 (+)NCBI
MGSCv3710128,143,314 - 128,157,294 (+)RGD
Celera10131,098,390 - 131,112,396 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006513405   ⟹   XP_006513468
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910128,540,936 - 128,555,993 (+)NCBI
GRCm3810128,705,059 - 128,720,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030244967   ⟹   XP_030100827
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910128,531,757 - 128,555,993 (+)NCBI
GRCm3810128,695,888 - 128,720,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036155712   ⟹   XP_036011605
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910128,541,961 - 128,555,993 (+)NCBI
Sequence:
RefSeq Acc Id: NP_068682   ⟸   NM_021882
- Peptide Label: precursor
- UniProtKB: Q60696 (UniProtKB/Swiss-Prot),   Q9CZB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006513468   ⟸   XM_006513405
- Peptide Label: isoform X1
- UniProtKB: Q60696 (UniProtKB/Swiss-Prot),   Q9CZB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030100827   ⟸   XM_030244967
- Peptide Label: isoform X1
- UniProtKB: Q60696 (UniProtKB/Swiss-Prot),   Q9CZB2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000151602   ⟸   ENSMUST00000217836
Ensembl Acc Id: ENSMUSP00000051869   ⟸   ENSMUST00000054125
Ensembl Acc Id: ENSMUSP00000151621   ⟸   ENSMUST00000219157
RefSeq Acc Id: XP_036011605   ⟸   XM_036155712
- Peptide Label: isoform X2
Protein Domains
PKAT KLD   PKD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q60696-F1-model_v2 AlphaFold Q60696 1-626 view protein structure

Promoters
RGD ID:6819926
Promoter ID:MM_KWN:6019
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day6,   BoneMarrow_0Hour,   MEF_B6,   Spleen
Transcripts:NM_021882
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610128,142,076 - 128,142,576 (+)MPROMDB
RGD ID:8673652
Promoter ID:EPDNEW_M14857
Type:single initiation site
Name:Pmel_1
Description:Mus musculus premelanosome protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810128,706,258 - 128,706,318EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98301 AgrOrtholog
Ensembl Genes ENSMUSG00000025359 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000054125 ENTREZGENE
  ENSMUST00000054125.9 UniProtKB/Swiss-Prot
  ENSMUST00000217836.2 UniProtKB/TrEMBL
  ENSMUST00000219157.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro Ig-like_fold UniProtKB/Swiss-Prot
  PKAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKAT_KLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKD/Chitinase_dom UniProtKB/Swiss-Prot
  PKD_dom UniProtKB/Swiss-Prot
  PKD_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:20431 UniProtKB/Swiss-Prot
MGD MGI:98301 ENTREZGENE
NCBI Gene 20431 ENTREZGENE
PANTHER MELANOCYTE PROTEIN PMEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11861 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PKAT_KLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKD UniProtKB/Swiss-Prot
PhenoGen Pmel PhenoGen
PROSITE PKD UniProtKB/Swiss-Prot
SMART PKD UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49299 UniProtKB/Swiss-Prot
UniProt A0A1W2P7B8_MOUSE UniProtKB/TrEMBL
  A0A1W2P7H5_MOUSE UniProtKB/TrEMBL
  PMEL_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9CZB2 ENTREZGENE
  Q9QY67_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q9CZB2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Pmel  premelanosome protein  Si  silver  Symbol and/or name change 5135510 APPROVED