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Gene: Pmel (premelanosome protein) Mus musculus
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Symbol: Pmel
Name: premelanosome protein
RGD ID: 1316752
Description: Predicted to have identical protein binding activity. Involved in melanin biosynthetic process and positive regulation of melanin biosynthetic process. Localizes to melanosome. Is expressed in several structures, including alimentary system; genitourinary system; mesenchyme derived from neural crest; nervous system; and sensory organ. Orthologous to human PMEL (premelanosome protein); INTERACTS WITH lead diacetate; trichloroethene; 3-isobutyl-1-methyl-7H-xanthine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D10H12S53; D10H12S53E; D12S53E; D12S53Eh; gp10; gp100; gp8; gp87; melanocyte protein PMEL; melanocyte protein Pmel 17; Pmel17; Si; Silv; silver locus protein
Orthologs:
Homo sapiens (human) : PMEL (premelanosome protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pmel (premelanosome protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pmel (premelanosome protein)
Pan paniscus (bonobo/pygmy chimpanzee) : PMEL (premelanosome protein)
Canis lupus familiaris (dog) : PMEL (premelanosome protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pmel (premelanosome protein)
Sus scrofa (pig) : PMEL (premelanosome protein)
Chlorocebus sabaeus (African green monkey) : PMEL (premelanosome protein)
Heterocephalus glaber (naked mole-rat) : Pmel (premelanosome protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl10128,704,195 - 128,720,238 (+)EnsemblGRCm38mm10GRCm38
GRCm3810128,695,888 - 128,720,238 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710128,143,314 - 128,157,294 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610128,109,207 - 128,123,073 (+)NCBImm8
Celera10131,098,390 - 131,112,396 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Pmel
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316752
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.