Fcamr (Fc receptor, IgA, IgM, high affinity) - Rat Genome Database

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Gene: Fcamr (Fc receptor, IgA, IgM, high affinity) Mus musculus
Analyze
Symbol: Fcamr
Name: Fc receptor, IgA, IgM, high affinity
RGD ID: 1316611
MGI Page MGI
Description: Enables IgA binding activity; IgM binding activity; and transmembrane signaling receptor activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within immune response. Predicted to be active in plasma membrane. Is expressed in brain; cerebellum; and spinal cord. Orthologous to human FCAMR (Fc alpha and mu receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fc alpha/mu receptor; Fc IgA/IgM receptor; Fca/m receptor; high affinity immunoglobulin alpha and immunoglobulin mu Fc receptor; mFcamR; MGC129330; MGC129331
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,712,444 - 130,753,641 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1130,728,639 - 130,742,477 (+)EnsemblGRCm39 Ensembl
GRCm381130,784,706 - 130,825,903 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,800,902 - 130,814,740 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,697,479 - 132,711,317 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,628,448 - 132,642,286 (+)NCBIMGSCv36mm8
Celera1133,424,202 - 133,438,043 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11062505   PMID:11797105   PMID:12477932   PMID:12527391   PMID:16681999   PMID:19027165   PMID:19549827   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22988094   PMID:23665380  
PMID:24172225   PMID:25282043   PMID:26385523   PMID:27146354   PMID:28747342   PMID:29459869   PMID:29507409   PMID:31471109  


Genomics

Comparative Map Data
Fcamr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391130,712,444 - 130,753,641 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1130,728,639 - 130,742,477 (+)EnsemblGRCm39 Ensembl
GRCm381130,784,706 - 130,825,903 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1130,800,902 - 130,814,740 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,697,479 - 132,711,317 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,628,448 - 132,642,286 (+)NCBIMGSCv36mm8
Celera1133,424,202 - 133,438,043 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map156.89NCBI
FCAMR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381206,957,967 - 206,970,638 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1206,957,965 - 206,970,625 (-)EnsemblGRCh38hg38GRCh38
GRCh371207,131,312 - 207,143,805 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361205,198,133 - 205,210,117 (-)NCBINCBI36Build 36hg18NCBI36
Celera1180,382,816 - 180,395,474 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1177,828,685 - 177,841,343 (-)NCBIHuRef
CHM1_11208,403,934 - 208,416,592 (-)NCBICHM1_1
T2T-CHM13v2.01206,223,168 - 206,235,839 (-)NCBIT2T-CHM13v2.0
Fcamr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81344,825,931 - 44,839,938 (+)NCBIGRCr8
mRatBN7.21342,273,891 - 42,288,002 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1342,273,628 - 42,287,113 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01347,538,052 - 47,552,370 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1347,539,231 - 47,552,848 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01352,626,937 - 52,641,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41343,752,437 - 43,764,514 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1342,622,036 - 42,636,354 (+)NCBICelera
Cytogenetic Map13q13NCBI
Fcamr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540642,484,614 - 42,496,672 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540642,484,811 - 42,518,714 (-)NCBIChiLan1.0ChiLan1.0
FCAMR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2142,403,436 - 42,415,684 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1142,369,137 - 42,381,632 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01182,561,953 - 182,574,818 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11186,840,337 - 186,853,189 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1186,841,103 - 186,852,689 (-)Ensemblpanpan1.1panPan2
FCAMR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.176,096,889 - 6,110,403 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl76,097,349 - 6,110,019 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha75,660,408 - 5,670,480 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.075,785,803 - 5,795,873 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl75,785,776 - 5,798,854 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.175,720,075 - 5,730,172 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.075,821,114 - 5,831,200 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.075,861,165 - 5,871,293 (-)NCBIUU_Cfam_GSD_1.0
Fcamr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934468,424,760 - 68,437,764 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365575,663,621 - 5,673,687 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FCAMR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1967,585,117 - 67,601,655 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2973,932,152 - 73,947,263 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103230183
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12522,389,223 - 22,398,341 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2522,389,314 - 22,398,499 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605523,053,887 - 23,062,730 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fcamr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248074,508,910 - 4,534,263 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:194
Count of miRNA genes:141
Interacting mature miRNAs:149
Transcripts:ENSMUST00000027670, ENSMUST00000112477
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
1357847Jckm2_mjuvenile cystic kidney modifier 2 (mouse)Not determined174991977133290937Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121727729139727738Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
1301753Tir3a_mtrypansomiasis infection response 3a (mouse)Not determined197053986131054190Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
1301536Pbbcp1_mperipheral blood B cell percentage 1 (mouse)Not determined199507660133507845Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000027670   ⟹   ENSMUSP00000027670
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1130,728,639 - 130,742,477 (+)Ensembl
GRCm38.p6 Ensembl1130,800,902 - 130,814,740 (+)Ensembl
Ensembl Acc Id: ENSMUST00000112477   ⟹   ENSMUSP00000108096
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1130,728,639 - 130,742,445 (+)Ensembl
GRCm38.p6 Ensembl1130,800,902 - 130,814,708 (+)Ensembl
RefSeq Acc Id: NM_001170632   ⟹   NP_001164103
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,728,639 - 130,742,477 (+)NCBI
GRCm381130,800,902 - 130,814,740 (+)NCBI
MGSCv371132,697,479 - 132,711,317 (+)RGD
Celera1133,424,202 - 133,438,043 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_144960   ⟹   NP_659209
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,728,639 - 130,742,477 (+)NCBI
GRCm381130,800,902 - 130,814,740 (+)NCBI
MGSCv371132,697,479 - 132,711,317 (+)RGD
Celera1133,424,202 - 133,438,043 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529787   ⟹   XP_006529850
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,712,444 - 130,747,053 (+)NCBI
GRCm381130,784,706 - 130,819,316 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321921   ⟹   XP_017177410
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,730,689 - 130,747,053 (+)NCBI
GRCm381130,802,952 - 130,819,316 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321922   ⟹   XP_017177411
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,730,689 - 130,747,053 (+)NCBI
GRCm381130,802,952 - 130,819,316 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321923   ⟹   XP_017177412
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,730,689 - 130,753,641 (+)NCBI
GRCm381130,802,952 - 130,825,903 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321924   ⟹   XP_017177413
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,730,689 - 130,747,053 (+)NCBI
GRCm381130,802,952 - 130,819,316 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321925   ⟹   XP_017177414
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391130,712,444 - 130,747,053 (+)NCBI
GRCm381130,784,706 - 130,819,316 (+)NCBI
Sequence:
RefSeq Acc Id: NP_659209   ⟸   NM_144960
- Peptide Label: isoform 2 precursor
- UniProtKB: Q920L8 (UniProtKB/Swiss-Prot),   Q2TB55 (UniProtKB/Swiss-Prot),   Q9EQT7 (UniProtKB/Swiss-Prot),   Q2TB54 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001164103   ⟸   NM_001170632
- Peptide Label: isoform 1
- UniProtKB: Q2TB54 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006529850   ⟸   XM_006529787
- Peptide Label: isoform X2
- UniProtKB: Q920L8 (UniProtKB/Swiss-Prot),   Q2TB55 (UniProtKB/Swiss-Prot),   Q9EQT7 (UniProtKB/Swiss-Prot),   Q2TB54 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017177414   ⟸   XM_017321925
- Peptide Label: isoform X2
- UniProtKB: Q920L8 (UniProtKB/Swiss-Prot),   Q2TB55 (UniProtKB/Swiss-Prot),   Q9EQT7 (UniProtKB/Swiss-Prot),   Q2TB54 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017177412   ⟸   XM_017321923
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017177410   ⟸   XM_017321921
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017177411   ⟸   XM_017321922
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017177413   ⟸   XM_017321924
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000027670   ⟸   ENSMUST00000027670
Ensembl Acc Id: ENSMUSP00000108096   ⟸   ENSMUST00000112477
Protein Domains
Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q2TB54-F1-model_v2 AlphaFold Q2TB54 1-535 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1927803 AgrOrtholog
Ensembl Genes ENSMUSG00000026415 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027670 ENTREZGENE
  ENSMUST00000027670.4 UniProtKB/Swiss-Prot
  ENSMUST00000112477 ENTREZGENE
  ENSMUST00000112477.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro CD300_family_receptors UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
KEGG Report mmu:64435 UniProtKB/Swiss-Prot
MGD MGI:1927803 ENTREZGENE
NCBI Gene 64435 ENTREZGENE
PANTHER HIGH AFFINITY IMMUNOGLOBULIN ALPHA AND IMMUNOGLOBULIN MU FC RECEPTOR UniProtKB/Swiss-Prot
  POLYMERIC-IMMUNOGLOBULIN RECEPTOR UniProtKB/Swiss-Prot
Pfam V-set UniProtKB/Swiss-Prot
PhenoGen Fcamr PhenoGen
SMART SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt FCAMR_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q2TB55 ENTREZGENE
  Q920L8 ENTREZGENE
  Q9EQT7 ENTREZGENE
UniProt Secondary Q2TB55 UniProtKB/Swiss-Prot
  Q920L8 UniProtKB/Swiss-Prot
  Q9EQT7 UniProtKB/Swiss-Prot