Serpinc1 (serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Serpinc1 (serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1) Mus musculus
Analyze
Symbol: Serpinc1
Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
RGD ID: 1316584
MGI Page MGI
Description: Predicted to enable several functions, including heparin binding activity; identical protein binding activity; and serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity and response to nutrient. Predicted to act upstream of or within blood coagulation and negative regulation of peptidase activity. Located in collagen-containing extracellular matrix. Is expressed in embryo; liver; neural tube; and notochord. Used to study antithrombin III deficiency. Human ortholog(s) of this gene implicated in antithrombin III deficiency; disseminated intravascular coagulation; intermediate coronary syndrome; thrombosis; and toxic shock syndrome. Orthologous to human SERPINC1 (serpin family C member 1); PARTICIPATES IN coagulation cascade pathway; enoxaparin pharmacodynamics pathway; fondaparinux pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A; AI114908; anti-thrombin 3; antithrombin; antithrombin-III; At; At-; At-3; At3; ATIII; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serpin C1; serpin peptidase inhibitor, clade C, member 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,806,153 - 160,830,113 (+)NCBIGRCm39mm39
GRCm39 Ensembl1160,806,155 - 160,833,433 (+)Ensembl
GRCm381160,978,583 - 161,002,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,978,585 - 161,005,863 (+)EnsemblGRCm38mm10GRCm38
MGSCv371162,908,737 - 162,933,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv361162,824,166 - 162,839,687 (+)NCBImm8
Celera1163,418,142 - 163,442,757 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map169.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
6-aminohexanoate  (ISO)
6-aminohexanoic acid  (ISO)
acetamide  (ISO)
aflatoxin B1  (EXP,ISO)
amidotrizoic acid  (ISO)
antimony(0)  (ISO)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
busulfan  (ISO)
buta-1,3-diene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chlorotrianisene  (ISO)
chromium atom  (ISO)
chromium trinitrate  (EXP)
clobazam  (ISO)
clofibrate  (EXP,ISO)
clothianidin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
cyclosporin A  (ISO)
dienogest  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
furan  (ISO)
gestodene  (ISO)
heparin  (EXP,ISO)
hydrogen peroxide  (ISO)
ioxaglic acid  (ISO)
levonorgestrel  (ISO)
Licochalcone B  (ISO)
medroxyprogesterone acetate  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
norethisterone  (ISO)
norgestimate  (ISO)
O-methyleugenol  (ISO)
oxybenzone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenformin  (ISO)
phenobarbital  (ISO)
phenytoin  (ISO)
potassium chromate  (EXP)
potassium dichromate  (EXP,ISO)
prednisone  (ISO)
quercetin  (ISO)
resveratrol  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sulfasalazine  (EXP)
tamoxifen  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toremifene  (ISO)
Triptolide  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Akman S, etal., Pediatr Nephrol. 2008 Aug;23(8):1327-30. doi: 10.1007/s00467-008-0829-7. Epub 2008 May 6.
2. al-Mugeiren MM, etal., Haemostasis. 1996 Nov-Dec;26(6):304-10.
3. Amagasa H, etal., J Atheroscler Thromb. 2005;12(4):191-8.
4. Caglikulekci M, etal., Ann Chir. 2004 Jun;129(5):273-7.
5. Camara-Lemarroy CR, etal., Arch Med Res. 2014 Apr;45(3):210-6. doi: 10.1016/j.arcmed.2014.02.001. Epub 2014 Apr 13.
6. Chan KC, etal., J Food Sci. 2012 Feb;77(2):H76-80. doi: 10.1111/j.1750-3841.2011.02558.x. Epub 2012 Feb 6.
7. Cicala C, etal., Eur J Pharmacol. 2007 Dec 22;577(1-3):156-61. Epub 2007 Aug 14.
8. Cruz C, etal., Nephron. 1994;68(4):489-96.
9. Czabanka M, etal., J Surg Res. 2006 Dec;136(2):219-26. Epub 2006 Feb 2.
10. Ding Q, etal., Thromb Res. 2013 Sep;132(3):367-73. doi: 10.1016/j.thromres.2013.07.013. Epub 2013 Aug 8.
11. Duru S, etal., Acta Anaesthesiol Scand. 2005 Sep;49(8):1142-8.
12. ElGendy AA and Abbas AM, J Physiol Biochem. 2014 Jun;70(2):535-46. doi: 10.1007/s13105-014-0333-4. Epub 2014 Mar 27.
13. Emerson TE Jr, etal., Am J Med. 1989 Sep 11;87(3B):27S-33S.
14. Erman T, etal., Neurosurgery. 2005 Apr;56(4):828-35.
15. Fujiwara K, etal., J Gastroenterol Hepatol. 1995;10 Suppl 1:S88-91.
16. Garcia-Avello A, etal., Thromb Res. 1998 Jan 15;89(2):59-64.
17. Gomibuchi H, etal., Exp Anim. 2007 Jan;56(1):1-10.
18. Guzman-De La Garza FJ, etal., Surg Today. 2010 Nov;40(11):1055-62. doi: 10.1007/s00595-009-4177-4. Epub 2010 Nov 3.
19. Hagiwara S, etal., Inflamm Res. 2010 Jul;59(7):511-8. doi: 10.1007/s00011-009-0155-y. Epub 2010 Jan 3.
20. Hagiwara S, etal., Intensive Care Med. 2008 Feb;34(2):361-7. Epub 2007 Oct 17.
21. Hagiwara S, etal., Pancreas. 2009 Oct;38(7):746-51. doi: 10.1097/MPA.0b013e3181aba9fa.
22. Harada N, etal., Thromb Haemost. 2006 Jun;95(6):1011-8.
23. Hassan S, etal., Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2959-65. Epub 2007 Feb 9.
24. Huang Y, etal., Eur J Obstet Gynecol Reprod Biol. 2012 Nov;165(1):96-103. doi: 10.1016/j.ejogrb.2012.06.031. Epub 2012 Jul 18.
25. Iba T, etal., Intensive Care Med. 2005 Aug;31(8):1101-8. Epub 2005 Jul 2.
26. Knobl P, etal., Thromb Haemost. 1994 Jun;71(6):692-7.
27. Kung CW, etal., Thromb Res. 2011 Jun;127(6):582-8. Epub 2011 Mar 10.
28. Kurata M, etal., World J Gastroenterol. 2006 Jan 7;12(1):60-5.
29. Lidon RM, etal., Thromb Res. 1993 Oct 1;72(1):23-32.
30. Lin CM, etal., Zhonghua Xue Ye Xue Za Zhi. 2012 Mar;33(3):215-9.
31. Maksan SM, etal., World J Gastroenterol. 2005 Aug 28;11(32):4997-5001.
32. MGD data from the GO Consortium
33. MGD IEA
34. Miyazaki M, etal., World J Gastroenterol. 2012 Apr 28;18(16):1884-91. doi: 10.3748/wjg.v18.i16.1884.
35. Norris LA, Best Pract Res Clin Obstet Gynaecol. 2003 Jun;17(3):369-83.
36. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
37. OMIM Disease Annotation Pipeline
38. Ong K, etal., Thromb Haemost 2000 Dec;84(6):1023-30.
39. Picard V, etal., Blood. 2003 Aug 1;102(3):919-25. Epub 2003 Feb 20.
40. Pipeline to import KEGG annotations from KEGG into RGD
41. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
42. Pipeline to import SMPDB annotations from SMPDB into RGD
43. RGD automated import pipeline
44. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
45. RGD automated import pipeline for gene-chemical interactions
46. Sacks SH, etal., J Med Genet. 1988 Jan;25(1):20-4.
47. Safdar H, etal., Blood. 2013 May 23;121(21):4413-6. doi: 10.1182/blood-2012-11-465674. Epub 2013 Apr 2.
48. Sun W, etal., Int Orthop. 2006 Jun;30(3):143-6. doi: 10.1007/s00264-005-0067-6. Epub 2006 Mar 18.
49. Sun W, etal., Zhonghua Yi Xue Za Zhi. 2006 Feb 21;86(7):442-5.
50. Tsai YC, etal., Eur J Pharmacol. 2010 Sep 1;641(1):67-73. Epub 2010 May 25.
51. Wang F, etal., Kidney Int. 2015 Oct;88(4):796-803. doi: 10.1038/ki.2015.176. Epub 2015 Jun 24.
52. Zee RY, etal., J Hypertens. 1991 Sep;9(9):825-30.
Additional References at PubMed
PMID:1440494   PMID:1617216   PMID:1672660   PMID:1676977   PMID:1683707   PMID:1693656   PMID:1694218   PMID:1970330   PMID:2498841   PMID:2531187   PMID:2567701   PMID:2574151  
PMID:2787796   PMID:2894402   PMID:3148667   PMID:3384439   PMID:3416634   PMID:7511063   PMID:7558021   PMID:7829095   PMID:7973732   PMID:8001974   PMID:8076595   PMID:8422330  
PMID:8530024   PMID:8589528   PMID:8827514   PMID:8896339   PMID:9250876   PMID:9422770   PMID:10349636   PMID:10489375   PMID:10515791   PMID:10613847   PMID:11018075   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:11722849   PMID:11895779   PMID:12477932   PMID:14592998   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16409467   PMID:16602821  
PMID:16944957   PMID:17015433   PMID:17330941   PMID:18798549   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22159717   PMID:24172014   PMID:30694755   PMID:30870413   PMID:32325033  


Genomics

Comparative Map Data
Serpinc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,806,153 - 160,830,113 (+)NCBIGRCm39mm39
GRCm39 Ensembl1160,806,155 - 160,833,433 (+)Ensembl
GRCm381160,978,583 - 161,002,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,978,585 - 161,005,863 (+)EnsemblGRCm38mm10GRCm38
MGSCv371162,908,737 - 162,933,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv361162,824,166 - 162,839,687 (+)NCBImm8
Celera1163,418,142 - 163,442,757 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map169.75NCBI
SERPINC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1173,903,800 - 173,917,327 (-)EnsemblGRCh38hg38GRCh38
GRCh381173,903,800 - 173,917,327 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371173,872,938 - 173,886,465 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361172,139,565 - 172,153,096 (-)NCBINCBI36hg18NCBI36
Build 341170,604,599 - 170,618,130NCBI
Celera1146,982,409 - 146,995,977 (-)NCBI
Cytogenetic Map1q25.1NCBI
HuRef1145,098,064 - 145,111,634 (-)NCBIHuRef
CHM1_11175,295,382 - 175,308,956 (-)NCBICHM1_1
Serpinc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21373,257,208 - 73,271,476 (+)NCBI
Rnor_6.0 Ensembl1378,805,347 - 78,833,192 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01378,806,107 - 78,820,375 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01383,700,761 - 83,715,029 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41376,548,456 - 76,562,724 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11376,562,643 - 76,576,911 (+)NCBI
Celera1373,045,672 - 73,059,940 (+)NCBICelera
Cytogenetic Map13q22NCBI
Serpinc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540614,024,313 - 14,035,948 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540614,024,183 - 14,036,206 (-)NCBIChiLan1.0ChiLan1.0
SERPINC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11153,126,031 - 153,139,369 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1153,126,031 - 153,139,369 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01149,421,737 - 149,435,301 (-)NCBIMhudiblu_PPA_v0panPan3
SERPINC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1725,322,668 - 25,333,022 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl725,316,129 - 25,332,987 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha724,855,807 - 24,866,147 (+)NCBI
ROS_Cfam_1.0725,073,311 - 25,083,857 (+)NCBI
UMICH_Zoey_3.1724,993,149 - 25,003,688 (+)NCBI
UNSW_CanFamBas_1.0725,074,836 - 25,085,380 (+)NCBI
UU_Cfam_GSD_1.0725,220,039 - 25,230,581 (+)NCBI
Serpinc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934496,134,261 - 96,146,884 (+)NCBI
SpeTri2.0NW_00493648113,981,014 - 13,993,750 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9116,181,980 - 116,193,201 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19116,181,988 - 116,193,100 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29127,817,120 - 127,828,237 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SERPINC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12555,271,823 - 55,289,855 (+)NCBI
Vero_WHO_p1.0NW_02366605556,831,874 - 56,851,329 (+)NCBI
Serpinc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247717,955,778 - 7,966,637 (+)NCBI

Position Markers
Serpinc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H2.1UniSTS
cM Map184.6UniSTS
AI114908  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381161,002,683 - 161,002,901UniSTSGRCm38
MGSCv371162,932,814 - 162,933,032UniSTSGRCm37
Celera1163,442,425 - 163,442,643UniSTS
Cytogenetic Map1H2.1UniSTS
Whitehead/MRC_RH12062.24UniSTS
RH129407  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381161,003,055 - 161,003,269UniSTSGRCm38
MGSCv371162,933,186 - 162,933,400UniSTSGRCm37
Celera1163,442,797 - 163,443,011UniSTS
Cytogenetic Map1H2.1UniSTS
Serpinc1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H2.1UniSTS
cM Map184.6UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139774467173774646Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135919071169919261Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157628733191628870Mouse
1301818Ap1q_malcohol preference 1 QTL (mouse)Not determined1147032461167758653Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155893961189895041Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156774467189571420Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139774467173774646Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157628733191628870Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157628733191628870Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129255120163255255Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139774467173774646Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
4141075Bmd1a_mbone mineral density 1a (mouse)Not determined1155962068162317756Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
1300837Vmbic1_mventral midbrain iron content 1 (mouse)Not determined1139624618173624738Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136334204170334348Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139774467173774646Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155888654189888802Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139774467173774646Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131228571165311895Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1156004198190004325Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139774467173774646Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157628733191628870Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139774467173774646Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157628733191628870Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1136002150170002264Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155699229189699330Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157628733191628870Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157628733191628870Mouse
1301232Hcs7_mhepatocarcinogenesis susceptibility 7 (mouse)Not determined1156774467168358833Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1156004198190004325Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156774467189571420Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112081092168358833Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1301164Tir3c_mtrypansomiasis infection response 3c (mouse)Not determined1154804480188804689Mouse
1357567Nidd3k_mNidd3 on KK-A<y> (mouse)Not determined7147249520169211344Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139624618173624738Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined156004198190004325Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155888654189888802Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155706491186261999Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154582944188582944Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155698056189699966Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
10449381Actre11_mactivity response to ethanol 11 (mouse)1160457095162012496Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195600000162200000Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122100000165000000Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155888654189888802Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147249520171804689Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
13452397Leusq4_mleucocytosis susceptibility QTL 4 (mouse)1156774467170976071Mouse
14746980Manh50_mmandible shape 50 (mouse)1134255813168255813Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121800000165000000Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139774467173774646Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156774467176435127Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155175373189175373Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
13452394Leusq1_mleucocytosis susceptibility QTL 1 (mouse)1156774467168358833Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155175373189175373Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155175373189175373Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1156004198190004325Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:175
Count of miRNA genes:147
Interacting mature miRNAs:167
Transcripts:ENSMUST00000064725
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000064725   ⟹   ENSMUSP00000068971
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,978,646 - 161,005,863 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191936   ⟹   ENSMUSP00000142122
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,978,652 - 160,993,632 (+)Ensembl
RefSeq Acc Id: ENSMUST00000193477
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,978,585 - 160,981,770 (+)Ensembl
RefSeq Acc Id: ENSMUST00000194455   ⟹   ENSMUSP00000141885
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,989,377 - 161,002,463 (+)Ensembl
RefSeq Acc Id: ENSMUST00000194592   ⟹   ENSMUSP00000141556
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,984,768 - 160,997,443 (+)Ensembl
RefSeq Acc Id: ENSMUST00000194777
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,987,087 - 160,989,748 (+)Ensembl
RefSeq Acc Id: ENSMUST00000195438   ⟹   ENSMUSP00000141834
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,978,606 - 160,997,414 (+)Ensembl
RefSeq Acc Id: ENSMUST00000195760   ⟹   ENSMUSP00000141864
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,978,688 - 160,989,658 (+)Ensembl
RefSeq Acc Id: NM_001379302   ⟹   NP_001366231
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,806,153 - 160,830,110 (+)NCBI
GRCm381160,978,583 - 161,002,540 (+)NCBI
RefSeq Acc Id: NM_080844   ⟹   NP_543120
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,806,153 - 160,830,110 (+)NCBI
GRCm381160,978,583 - 161,002,540 (+)NCBI
MGSCv371162,908,737 - 162,933,146 (+)RGD
Celera1163,418,142 - 163,442,757 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006496626   ⟹   XP_006496689
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,812,372 - 160,830,113 (+)NCBI
GRCm381160,984,802 - 161,002,543 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030243696   ⟹   XP_030099556
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,814,685 - 160,830,113 (+)NCBI
GRCm381160,987,127 - 161,002,543 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_543120   ⟸   NM_080844
- Peptide Label: isoform 1 precursor
- UniProtKB: P32261 (UniProtKB/Swiss-Prot),   Q543J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006496689   ⟸   XM_006496626
- Peptide Label: isoform X1
- UniProtKB: P32261 (UniProtKB/Swiss-Prot),   Q543J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030099556   ⟸   XM_030243696
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001366231   ⟸   NM_001379302
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000142122   ⟸   ENSMUST00000191936
RefSeq Acc Id: ENSMUSP00000141885   ⟸   ENSMUST00000194455
RefSeq Acc Id: ENSMUSP00000141556   ⟸   ENSMUST00000194592
RefSeq Acc Id: ENSMUSP00000068971   ⟸   ENSMUST00000064725
RefSeq Acc Id: ENSMUSP00000141864   ⟸   ENSMUST00000195760
RefSeq Acc Id: ENSMUSP00000141834   ⟸   ENSMUST00000195438
Protein Domains
SERPIN

Promoters
RGD ID:6875422
Promoter ID:EPDNEW_M1162
Type:initiation region
Name:Serpinc1_1
Description:Mus musculus serine peptidase inhibitor, clade C , member 1 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381160,987,512 - 160,987,572EPDNEW
RGD ID:6818448
Promoter ID:MM_KWN:2603
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Liver,   MEF_B6
Transcripts:NM_080844
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361162,907,876 - 162,908,927 (+)MPROMDB
RGD ID:6818450
Promoter ID:MM_KWN:2604
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:UC007DEN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361162,917,391 - 162,917,891 (+)MPROMDB
RGD ID:6848554
Promoter ID:MM_TRO:573
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:MTR002994.1.2414.5,   MTR002994.1.2414.6
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361162,919,311 - 162,919,811 (+)MPROMDB
RGD ID:6846650
Promoter ID:MM_ACW:2941
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Liver
Transcripts:SERPINC1.GSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361162,927,376 - 162,927,876 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88095 AgrOrtholog
Ensembl Genes ENSMUSG00000026715 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000068971 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141556 UniProtKB/TrEMBL
  ENSMUSP00000141834 UniProtKB/TrEMBL
  ENSMUSP00000141864 UniProtKB/TrEMBL
  ENSMUSP00000141885 UniProtKB/TrEMBL
  ENSMUSP00000142122 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000064725 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000191936 UniProtKB/TrEMBL
  ENSMUST00000194455 UniProtKB/TrEMBL
  ENSMUST00000194592 UniProtKB/TrEMBL
  ENSMUST00000195438 UniProtKB/TrEMBL
  ENSMUST00000195760 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Antithrombin_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AT-III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88095 ENTREZGENE
NCBI Gene 11905 ENTREZGENE
PANTHER PTHR11461 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11461:SF53 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Serpin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Serpinc1 PhenoGen
PROSITE SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SERPIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56574 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YWH7_MOUSE UniProtKB/TrEMBL
  A0A0A6YX49_MOUSE UniProtKB/TrEMBL
  A0A0A6YX70_MOUSE UniProtKB/TrEMBL
  A0A0A6YX85_MOUSE UniProtKB/TrEMBL
  A0A0A6YXS8_MOUSE UniProtKB/TrEMBL
  ANT3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q543J5 ENTREZGENE, UniProtKB/TrEMBL