Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Serpinc1 (serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1) Mus musculus
Analyze
Symbol: Serpinc1
Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
Description: Predicted to have several functions, including heparin binding activity; identical protein binding activity; and serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity and response to nutrient. Localizes to the collagen-containing extracellular matrix. Used to study antithrombin III deficiency. Human ortholog(s) of this gene implicated in antithrombin III deficiency; disseminated intravascular coagulation; intermediate coronary syndrome; thrombosis; and toxic shock syndrome. Is expressed in embryo; liver; neural tube; and notochord. Orthologous to human SERPINC1 (serpin family C member 1); PARTICIPATES IN coagulation cascade pathway; enoxaparin pharmacodynamics pathway; fondaparinux pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI114908; anti-thrombin 3; antithrombin; antithrombin-III; At-3; At3; ATIII; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serpin C1; serpin peptidase inhibitor, clade C, member 1
Orthologs:
Homo sapiens (human) : SERPINC1 (serpin family C member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Serpinc1 (serpin family C member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinc1 (serpin family C member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINC1 (serpin family C member 1)
Canis lupus familiaris (dog) : SERPINC1 (serpin family C member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinc1 (serpin family C member 1)
Sus scrofa (pig) : SERPINC1 (serpin family C member 1)
Chlorocebus sabaeus (green monkey) : SERPINC1 (serpin family C member 1)
Heterocephalus glaber (naked mole-rat) : Serpinc1 (serpin family C member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1160,978,585 - 161,005,863 (+)Ensembl
GRCm381160,978,606 - 161,003,015 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371162,908,737 - 162,933,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv361162,824,166 - 162,839,687 (+)NCBImm8
Celera1163,418,142 - 163,442,757 (+)NCBICelera
Cytogenetic Map1 H2.1NCBI
cM Map169.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Serpinc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316584
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.