Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | EXP | | 6480464 | ethylene dichloride results in increased expression of IGDCC3 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of IGDCC3 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IGDCC3 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of IGDCC3 mRNA | CTD | PMID:19167446 and PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IGDCC3 mRNA | CTD | PMID:17942748 | 4,4'-sulfonyldiphenol | decreases expression | EXP | | 6480464 | bisphenol S results in decreased expression of IGDCC3 mRNA | CTD | PMID:30951980 | acrylamide | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of IGDCC3 mRNA | CTD | PMID:32763439 | Aflatoxin B2 alpha | increases methylation | ISO | IGDCC3 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of IGDCC3 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | Tretinoin results in increased expression of IGDCC3 mRNA | CTD | PMID:20488242 | all-trans-retinoic acid | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of IGDCC3 mRNA | CTD | PMID:21934132 and PMID:23724009 | atrazine | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Atrazine results in increased expression of IGDCC3 mRNA | CTD | PMID:22378314 | azathioprine | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Azathioprine results in decreased expression of IGDCC3 mRNA | CTD | PMID:22623647 | benzo[a]pyrene | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of IGDCC3 mRNA | CTD | PMID:20106945 and PMID:21632981 | benzo[a]pyrene | affects methylation | ISO | IGDCC3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of IGDCC3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of IGDCC3 mRNA | CTD | PMID:27195522 | bisphenol A | affects expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | bisphenol A affects the expression of IGDCC3 mRNA | CTD | PMID:30903817 | bromobenzene | decreases expression | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | bromobenzene results in decreased expression of IGDCC3 mRNA | CTD | PMID:32479839 | butanal | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of IGDCC3 mRNA | CTD | PMID:26079696 | Butylparaben | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | butylparaben results in increased expression of IGDCC3 mRNA | CTD | PMID:17121429 | cadmium dichloride | increases methylation | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased methylation of IGDCC3 promoter | CTD | PMID:22457795 | clofibrate | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of IGDCC3 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IGDCC3 mRNA] | CTD | PMID:17585979 | clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of IGDCC3 mRNA | CTD | PMID:17585979 | copper(II) sulfate | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of IGDCC3 mRNA | CTD | PMID:19549813 | Cuprizon | decreases expression | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of IGDCC3 mRNA | CTD | PMID:26577399 | cyclosporin A | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of IGDCC3 mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | increases expression | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | decabromobiphenyl ether results in increased expression of IGDCC3 mRNA | CTD | PMID:23640034 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of IGDCC3 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | IGDCC3 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of IGDCC3 mRNA | CTD | PMID:29391264 | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Arbutin results in decreased expression of IGDCC3 mRNA | CTD | PMID:17103032 | lead(0) | affects expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Lead affects the expression of IGDCC3 mRNA | CTD | PMID:28903495 | methylmercury chloride | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of IGDCC3 mRNA | CTD | PMID:28001369 | methylparaben | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | methylparaben results in increased expression of IGDCC3 mRNA | CTD | PMID:17121429 | p-chloromercuribenzoic acid | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of IGDCC3 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | IGDCC3 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of IGDCC3 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | panobinostat results in increased expression of IGDCC3 mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | IGDCC3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGDCC3 mRNA | CTD | PMID:27188386 | paracetamol | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of IGDCC3 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IGDCC3 mRNA] | CTD | PMID:17585979 | pentanal | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | pentanal results in increased expression of IGDCC3 mRNA | CTD | PMID:26079696 | quercetin | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of IGDCC3 mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | IGDCC3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of IGDCC3 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | IGDCC3 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | increases expression | EXP | | 6480464 | Silver results in increased expression of IGDCC3 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | EXP | | 6480464 | Silver results in increased expression of IGDCC3 mRNA | CTD | PMID:27131904 | sodium arsenite | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of IGDCC3 mRNA | CTD | PMID:34032870 | sodium arsenite | multiple interactions | ISO | IGDCC3 (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [IGDCC3 protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of IGDCC3 mRNA | CTD | PMID:37682722 | sunitinib | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of IGDCC3 mRNA | CTD | PMID:31533062 | Theaflavin 3,3'-digallate | affects expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | theaflavin-3 and 3'-digallate affects the expression of IGDCC3 mRNA | CTD | PMID:34925699 | thimerosal | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of IGDCC3 mRNA | CTD | PMID:27188386 | thioacetamide | decreases expression | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of IGDCC3 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichostatin A | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of IGDCC3 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | IGDCC3 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGDCC3 mRNA | CTD | PMID:27188386 | Triptolide | increases expression | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | triptolide results in increased expression of IGDCC3 protein | CTD | PMID:32519852 | triticonazole | decreases expression | ISO | Igdcc3 (Rattus norvegicus) | 6480464 | triticonazole results in decreased expression of IGDCC3 mRNA | CTD | PMID:36084822 | urethane | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of IGDCC3 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of IGDCC3 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of IGDCC3 mRNA | CTD | PMID:24935251 | valproic acid | decreases expression | ISO | IGDCC3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of IGDCC3 mRNA | CTD | PMID:23179753 more ... | |