CENPM (centromere protein M) - Rat Genome Database

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Gene: CENPM (centromere protein M) Homo sapiens
Analyze
Symbol: CENPM
Name: centromere protein M
RGD ID: 1316428
HGNC Page HGNC
Description: Located in cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bK250D10.2; C22orf18; CENP-M; chromosome 22 open reading frame 18; interphase centromere complex protein 39; MGC861; PANE1; proliferation associated nuclear element 1; proliferation-associated nuclear element protein 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,938,737 - 41,947,152 (-)EnsemblGRCh38hg38GRCh38
GRCh382241,927,747 - 41,947,152 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,334,741 - 42,343,156 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,664,687 - 40,673,094 (-)NCBINCBI36hg18NCBI36
Build 342240,659,241 - 40,667,648NCBI
Celera2226,140,977 - 26,149,371 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2225,300,335 - 25,309,447 (-)NCBIHuRef
CHM1_12242,294,942 - 42,303,381 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IEA)
cytosol  (IDA,TAS)
kinetochore  (IEA)
nucleoplasm  (TAS)
nucleus  (IEA)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10591208   PMID:12477932   PMID:12529303   PMID:14702039   PMID:15009096   PMID:15183305   PMID:15461802   PMID:15489334   PMID:16391015   PMID:16622419   PMID:16622420   PMID:16716197  
PMID:19533115   PMID:19773279   PMID:23202124   PMID:24553122   PMID:24981860   PMID:25006165   PMID:25056061   PMID:25775162   PMID:26186194   PMID:26496610   PMID:26949251   PMID:28514442  
PMID:30033366   PMID:31343991   PMID:31617661   PMID:31703591   PMID:32663252   PMID:32694731   PMID:32705259   PMID:33000180  


Genomics

Comparative Map Data
CENPM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2241,938,737 - 41,947,152 (-)EnsemblGRCh38hg38GRCh38
GRCh382241,927,747 - 41,947,152 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,334,741 - 42,343,156 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,664,687 - 40,673,094 (-)NCBINCBI36hg18NCBI36
Build 342240,659,241 - 40,667,648NCBI
Celera2226,140,977 - 26,149,371 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2225,300,335 - 25,309,447 (-)NCBIHuRef
CHM1_12242,294,942 - 42,303,381 (-)NCBICHM1_1
Cenpm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391582,115,694 - 82,128,974 (-)NCBIGRCm39mm39
GRCm39 Ensembl1582,117,980 - 82,128,949 (-)Ensembl
GRCm381582,233,762 - 82,244,773 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1582,233,779 - 82,244,748 (-)EnsemblGRCm38mm10GRCm38
MGSCv371582,064,192 - 82,075,177 (-)NCBIGRCm37mm9NCBIm37
MGSCv361582,061,848 - 82,072,513 (-)NCBImm8
Celera1584,357,816 - 84,368,798 (-)NCBICelera
Cytogenetic Map15E1NCBI
Cenpm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27113,748,026 - 113,759,296 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl7113,747,516 - 113,764,258 (-)Ensembl
Rnor_6.07123,464,615 - 123,476,336 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,464,490 - 123,476,238 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,449,297 - 123,461,064 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,607,395 - 120,619,299 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,641,400 - 120,653,486 (-)NCBI
Celera7110,063,181 - 110,074,319 (-)NCBICelera
Cytogenetic Map7q34NCBI
Cenpm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541327,349,283 - 27,360,052 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541327,349,283 - 27,360,052 (-)NCBIChiLan1.0ChiLan1.0
LOC100990934
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12240,915,404 - 40,923,765 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2240,915,404 - 40,923,765 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02222,831,313 - 22,839,947 (-)NCBIMhudiblu_PPA_v0panPan3
CENPM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,413,177 - 23,425,559 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,412,393 - 23,425,981 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,347,239 - 23,359,600 (+)NCBI
ROS_Cfam_1.01024,158,132 - 24,170,505 (+)NCBI
UMICH_Zoey_3.11023,875,139 - 23,887,501 (+)NCBI
UNSW_CanFamBas_1.01024,196,181 - 24,208,759 (+)NCBI
UU_Cfam_GSD_1.01024,370,522 - 24,382,884 (+)NCBI
Cenpm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,064,736 - 7,078,276 (+)NCBI
SpeTri2.0NW_00493649275,196 - 88,446 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl56,677,716 - 6,690,308 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.156,677,607 - 6,690,322 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CENPM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11924,471,420 - 24,481,271 (-)NCBI
ChlSab1.1 Ensembl1924,471,178 - 24,481,239 (-)Ensembl
Vero_WHO_p1.0NW_023666045100,931,131 - 100,941,179 (+)NCBI
Cenpm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247526,781,504 - 6,790,520 (+)NCBI

Position Markers
RH91321  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,334,971 - 42,335,117UniSTSGRCh37
Build 362240,664,917 - 40,665,063RGDNCBI36
Celera2226,141,207 - 26,141,353RGD
Cytogenetic Map22q13.2UniSTS
HuRef2225,300,565 - 25,300,711UniSTS
GeneMap99-GB4 RH Map22137.51UniSTS
GDB:313501  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,341,974 - 42,343,424UniSTSGRCh37
GRCh377150,044,097 - 150,044,401UniSTSGRCh37
Build 367149,675,030 - 149,675,334RGDNCBI36
Celera2226,148,197 - 26,149,647UniSTS
Celera7144,601,187 - 144,601,491RGD
Cytogenetic Map22q13.2UniSTS
HuRef7143,860,604 - 143,860,896UniSTS
HuRef2225,308,273 - 25,309,723UniSTS
CRA_TCAGchr7v27149,381,948 - 149,382,252UniSTS
SHGC-37658  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372242,334,754 - 42,334,880UniSTSGRCh37
Build 362240,664,700 - 40,664,826RGDNCBI36
Celera2226,140,990 - 26,141,116RGD
Cytogenetic Map22q13.2UniSTS
HuRef2225,300,348 - 25,300,474UniSTS
Stanford-G3 RH Map221318.0UniSTS
NCBI RH Map22201.2UniSTS
GeneMap99-G3 RH Map221318.0UniSTS
RH36905  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map12q24.11UniSTS
Cytogenetic Map1p21.2UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map1p12UniSTS
Cytogenetic Map10p12.33UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map18p11.3-p11.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map14q24.1UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map3q27-q28UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map3q26.3UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.32UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map14q13.2UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map20p11.23UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map3q12.2-q12.3UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map1q21.2-q21.3UniSTS
Cytogenetic Map18q21UniSTS
Cytogenetic Map12q24.2-q24.31UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map16q22UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map11q12-q13.1UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map9q21.33UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map11p15.1UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map18p11.2UniSTS
Cytogenetic Map19q13.3-q13.4UniSTS
Cytogenetic Map9q31.1UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map6p24-p22.3UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map2p13UniSTS
Cytogenetic Map7q31.1-q31.2UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map10q21UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map4q25-q27UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map4q28-q32UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map10q24.1UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map11q14.1UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map1p21.3UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map3p25.1UniSTS
Cytogenetic Map10q25-q26UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map7p14UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map16q22.1UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2433
Count of miRNA genes:671
Interacting mature miRNAs:766
Transcripts:ENST00000215980, ENST00000396437, ENST00000402338, ENST00000402420, ENST00000404067, ENST00000407253, ENST00000460824, ENST00000472374
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 353 52 94 79 834 82 317 55 109 90 656 330 9 3 16 2
Low 997 1277 1066 337 1007 178 2422 489 2382 273 627 1099 162 1 638 1512 2 1
Below cutoff 1023 1534 547 194 107 192 1524 1562 1220 55 168 182 2 549 1176 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001002876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001110215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_024053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011530368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK123479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL160131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE789455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE797487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG476718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM045658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ652721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ922403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU556693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX332140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX354019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX417558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA414668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR456399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR457392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU035297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY095078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z99716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000215980   ⟹   ENSP00000215980
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,938,737 - 41,947,152 (-)Ensembl
RefSeq Acc Id: ENST00000396437
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,944,921 - 41,947,151 (-)Ensembl
RefSeq Acc Id: ENST00000402338   ⟹   ENSP00000384731
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,938,737 - 41,946,693 (-)Ensembl
RefSeq Acc Id: ENST00000402420   ⟹   ENSP00000384132
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,939,172 - 41,946,729 (-)Ensembl
RefSeq Acc Id: ENST00000404067   ⟹   ENSP00000384814
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,938,737 - 41,946,688 (-)Ensembl
RefSeq Acc Id: ENST00000407253   ⟹   ENSP00000384743
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,938,749 - 41,947,136 (-)Ensembl
RefSeq Acc Id: ENST00000460824
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,946,308 - 41,947,133 (-)Ensembl
RefSeq Acc Id: ENST00000472374   ⟹   ENSP00000430624
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2241,938,737 - 41,940,219 (-)Ensembl
RefSeq Acc Id: NM_001002876   ⟹   NP_001002876
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,938,737 - 41,947,152 (-)NCBI
GRCh372242,334,531 - 42,343,155 (-)NCBI
Build 362240,664,687 - 40,673,094 (-)NCBI Archive
Celera2226,140,977 - 26,149,371 (-)RGD
HuRef2225,300,335 - 25,309,447 (-)RGD
CHM1_12242,294,926 - 42,303,401 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001110215   ⟹   NP_001103685
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,938,737 - 41,940,219 (-)NCBI
GRCh372242,334,531 - 42,343,155 (-)NCBI
Celera2226,140,977 - 26,149,371 (-)RGD
HuRef2225,300,335 - 25,309,447 (-)RGD
CHM1_12242,294,926 - 42,296,452 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001304370   ⟹   NP_001291299
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,938,737 - 41,946,738 (-)NCBI
CHM1_12242,294,926 - 42,302,991 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001304371   ⟹   NP_001291300
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,944,921 - 41,947,152 (-)NCBI
CHM1_12242,301,158 - 42,303,401 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001304372   ⟹   NP_001291301
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,938,737 - 41,946,738 (-)NCBI
CHM1_12242,294,926 - 42,302,991 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001304373   ⟹   NP_001291302
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,938,737 - 41,946,738 (-)NCBI
CHM1_12242,294,926 - 42,302,991 (-)NCBI
Sequence:
RefSeq Acc Id: NM_024053   ⟹   NP_076958
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,938,737 - 41,947,152 (-)NCBI
GRCh372242,334,531 - 42,343,155 (-)NCBI
Build 362240,664,687 - 40,673,094 (-)NCBI Archive
Celera2226,140,977 - 26,149,371 (-)RGD
HuRef2225,300,335 - 25,309,447 (-)RGD
CHM1_12242,294,926 - 42,303,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011530368   ⟹   XP_011528670
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,927,747 - 41,947,151 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001002876   ⟸   NM_001002876
- Peptide Label: isoform b
- UniProtKB: Q9NSP4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_076958   ⟸   NM_024053
- Peptide Label: isoform a
- UniProtKB: Q9NSP4 (UniProtKB/Swiss-Prot),   A0A024R1Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103685   ⟸   NM_001110215
- Peptide Label: isoform c
- UniProtKB: Q9NSP4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001291302   ⟸   NM_001304373
- Peptide Label: isoform g
- UniProtKB: Q9NSP4 (UniProtKB/Swiss-Prot),   B1AHQ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001291299   ⟸   NM_001304370
- Peptide Label: isoform d
- UniProtKB: Q9NSP4 (UniProtKB/Swiss-Prot),   B1AHQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001291301   ⟸   NM_001304372
- Peptide Label: isoform f
- UniProtKB: Q9NSP4 (UniProtKB/Swiss-Prot),   B1AHQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001291300   ⟸   NM_001304371
- Peptide Label: isoform e
- UniProtKB: Q9NSP4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011528670   ⟸   XM_011530368
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000215980   ⟸   ENST00000215980
RefSeq Acc Id: ENSP00000384731   ⟸   ENST00000402338
RefSeq Acc Id: ENSP00000384132   ⟸   ENST00000402420
RefSeq Acc Id: ENSP00000384814   ⟸   ENST00000404067
RefSeq Acc Id: ENSP00000384743   ⟸   ENST00000407253
RefSeq Acc Id: ENSP00000430624   ⟸   ENST00000472374

Promoters
RGD ID:6799755
Promoter ID:HG_KWN:43031
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   K562,   Lymphoblastoid
Transcripts:NM_001110215
Position:
Human AssemblyChrPosition (strand)Source
Build 362240,666,056 - 40,666,997 (-)MPROMDB
RGD ID:6814694
Promoter ID:HG_XEF:5291
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour,   Lymphoblastoid
Transcripts:NM_001044638
Position:
Human AssemblyChrPosition (strand)Source
Build 362240,671,864 - 40,672,364 (-)MPROMDB
RGD ID:6799871
Promoter ID:HG_KWN:43032
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000396437,   ENST00000402338,   ENST00000402420,   ENST00000404067,   NM_001002876,   OTTHUMT00000322058,   OTTHUMT00000322064,   UC003BBP.1
Position:
Human AssemblyChrPosition (strand)Source
Build 362240,672,551 - 40,673,051 (-)MPROMDB
RGD ID:13604294
Promoter ID:EPDNEW_H28331
Type:initiation region
Name:CENPM_2
Description:centromere protein M
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28332  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,940,215 - 41,940,275EPDNEW
RGD ID:13604298
Promoter ID:EPDNEW_H28332
Type:initiation region
Name:CENPM_1
Description:centromere protein M
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H28331  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382241,947,123 - 41,947,183EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 22q12.3-13.33(chr22:33768441-50739977)x3 copy number gain See cases [RCV000051682] Chr22:33768441..50739977 [GRCh38]
Chr22:34164428..51178405 [GRCh37]
Chr22:32494428..49525271 [NCBI36]
Chr22:22q12.3-13.33
pathogenic
GRCh38/hg38 22q12.3-13.33(chr22:37061769-50738932)x3 copy number gain See cases [RCV000051684] Chr22:37061769..50738932 [GRCh38]
Chr22:37457809..51177360 [GRCh37]
Chr22:35787755..49524226 [NCBI36]
Chr22:22q12.3-13.33
pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916608-50739836)x3 copy number gain See cases [RCV000133646] Chr22:16916608..50739836 [GRCh38]
Chr22:17397498..51178264 [GRCh37]
Chr22:15777498..49525130 [NCBI36]
Chr22:22q11.1-13.33
pathogenic
GRCh38/hg38 22q11.1-13.33(chr22:16916743-50739785)x3 copy number gain See cases [RCV000134730] Chr22:16916743..50739785 [GRCh38]
Chr22:17397633..51178213 [GRCh37]
Chr22:15777633..49525079 [NCBI36]
Chr22:22q11.1-13.33
pathogenic
GRCh38/hg38 22q13.1-13.33(chr22:40202014-50735806)x3 copy number gain See cases [RCV000134513] Chr22:40202014..50735806 [GRCh38]
Chr22:40598018..51174234 [GRCh37]
Chr22:38927964..49521100 [NCBI36]
Chr22:22q13.1-13.33
pathogenic
GRCh38/hg38 22q13.2(chr22:41645339-42565798)x1 copy number loss See cases [RCV000136528] Chr22:41645339..42565798 [GRCh38]
Chr22:42041343..42961804 [GRCh37]
Chr22:40371289..41291748 [NCBI36]
Chr22:22q13.2
uncertain significance
GRCh38/hg38 22q13.2-13.33(chr22:41871143-50739836)x1 copy number loss See cases [RCV000136921] Chr22:41871143..50739836 [GRCh38]
Chr22:42267147..51178264 [GRCh37]
Chr22:40597093..49525130 [NCBI36]
Chr22:22q13.2-13.33
pathogenic
GRCh38/hg38 22q13.2(chr22:41277822-42414957)x3 copy number gain See cases [RCV000136785] Chr22:41277822..42414957 [GRCh38]
Chr22:41673826..42810963 [GRCh37]
Chr22:40003772..41140907 [NCBI36]
Chr22:22q13.2
pathogenic
GRCh38/hg38 22q13.2(chr22:41764466-41998153)x3 copy number gain See cases [RCV000142720] Chr22:41764466..41998153 [GRCh38]
Chr22:42160470..42394157 [GRCh37]
Chr22:40490416..40724103 [NCBI36]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51237518)x3 copy number gain See cases [RCV000240091] Chr22:16054691..51237518 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.2(chr22:42207144-42776457)x1 copy number loss See cases [RCV000240146] Chr22:42207144..42776457 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q12.3-13.33(chr22:35728929-51220961)x3 copy number gain See cases [RCV000240469] Chr22:35728929..51220961 [GRCh37]
Chr22:22q12.3-13.33
pathogenic
GRCh37/hg19 22q13.1-13.33(chr22:40425714-51220961)x3 copy number gain See cases [RCV000240459] Chr22:40425714..51220961 [GRCh37]
Chr22:22q13.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51220902)x3 copy number gain See cases [RCV000446956] Chr22:16054691..51220902 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16054691-51237463)x3 copy number gain See cases [RCV000448847] Chr22:16054691..51237463 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.2(chr22:41835094-42756616)x3 copy number gain See cases [RCV000511241] Chr22:41835094..42756616 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16888900-51197838) copy number gain See cases [RCV000510873] Chr22:16888900..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16888900-51197838)x3 copy number gain See cases [RCV000512333] Chr22:16888900..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
NC_000022.11:g.(?_41301335)_(42070317_?)del deletion Common variable immunodeficiency 4 [RCV000648330] Chr22:41301335..42070317 [GRCh38]
Chr22:41697339..42466321 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q13.2(chr22:41849322-42756616)x3 copy number gain not provided [RCV000684486] Chr22:41849322..42756616 [GRCh37]
Chr22:22q13.2
likely pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16888899-51197838)x3 copy number gain not provided [RCV000846344] Chr22:16888899..51197838 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16054667-51243435)x3 copy number gain not provided [RCV000741689] Chr22:16054667..51243435 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16114244-51195728)x3 copy number gain not provided [RCV000741691] Chr22:16114244..51195728 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q13.2-13.33(chr22:42151555-51195728)x1 copy number loss not provided [RCV000741989] Chr22:42151555..51195728 [GRCh37]
Chr22:22q13.2-13.33
pathogenic
GRCh37/hg19 22q11.1-13.33(chr22:16114244-51211392)x3 copy number gain not provided [RCV000741692] Chr22:16114244..51211392 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
GRCh37/hg19 22q12.2-13.33(chr22:30654764-51197838)x3 copy number gain not provided [RCV001007181] Chr22:30654764..51197838 [GRCh37]
Chr22:22q12.2-13.33
pathogenic
GRCh37/hg19 22q13.1-13.33(chr22:40502364-51197838)x3 copy number gain not provided [RCV001007502] Chr22:40502364..51197838 [GRCh37]
Chr22:22q13.1-13.33
pathogenic
GRCh37/hg19 22q13.2(chr22:41853620-42385978)x1 copy number loss not provided [RCV001258783] Chr22:41853620..42385978 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q13.2(chr22:42158393-42409550)x3 copy number gain not provided [RCV001258784] Chr22:42158393..42409550 [GRCh37]
Chr22:22q13.2
uncertain significance
GRCh37/hg19 22q11.1-13.33(chr22:16197005-51224252)x3 copy number gain See cases [RCV001263056] Chr22:16197005..51224252 [GRCh37]
Chr22:22q11.1-13.33
pathogenic
Single allele deletion Intellectual disability [RCV001293376] Chr22:42333802..51195728 [GRCh37]
Chr22:22q13.2-13.33
pathogenic
NC_000022.10:g.(?_41697339)_(42466321_?)del deletion Common variable immunodeficiency 4 [RCV001305750] Chr22:41697339..42466321 [GRCh37]
Chr22:22q13.2
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:18352 AgrOrtholog
COSMIC CENPM COSMIC
Ensembl Genes ENSG00000100162 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000215980 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000384132 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000384731 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000384743 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000384814 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000430624 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000215980 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000396437 ENTREZGENE
  ENST00000402338 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000402420 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000404067 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000407253 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000472374 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000100162 GTEx
HGNC ID HGNC:18352 ENTREZGENE
Human Proteome Map CENPM Human Proteome Map
InterPro Centromere_Cenp-M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:79019 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 79019 ENTREZGENE
OMIM 610152 OMIM
PANTHER PTHR34436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CENP-M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA25885 PharmGKB
UniProt A0A024R1Q3 ENTREZGENE, UniProtKB/TrEMBL
  B1AHQ6 ENTREZGENE, UniProtKB/TrEMBL
  B1AHQ7 ENTREZGENE, UniProtKB/TrEMBL
  B1AHQ8 ENTREZGENE, UniProtKB/TrEMBL
  CENPM_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A7LM22 UniProtKB/Swiss-Prot
  B1AHQ9 UniProtKB/Swiss-Prot
  Q6I9W3 UniProtKB/Swiss-Prot