Pnma2 (paraneoplastic antigen MA2) - Rat Genome Database

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Gene: Pnma2 (paraneoplastic antigen MA2) Mus musculus
Analyze
Symbol: Pnma2
Name: paraneoplastic antigen MA2
RGD ID: 1316358
MGI Page MGI
Description: Predicted to be located in nucleus. Is expressed in nervous system. Orthologous to human PNMA2 (PNMA family member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A830049P17Rik; KIAA0883; mKIAA0883; paraneoplastic antigen Ma2 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391467,139,038 - 67,157,512 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1467,148,619 - 67,158,472 (+)EnsemblGRCm39 Ensembl
GRCm381466,901,589 - 66,920,063 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1466,911,170 - 66,921,023 (+)EnsemblGRCm38mm10GRCm38
MGSCv371467,530,045 - 67,538,898 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361465,869,515 - 65,874,167 (+)NCBIMGSCv36mm8
Celera1464,664,973 - 64,673,798 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.6NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:21267068   PMID:35187673  


Genomics

Comparative Map Data
Pnma2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391467,139,038 - 67,157,512 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1467,148,619 - 67,158,472 (+)EnsemblGRCm39 Ensembl
GRCm381466,901,589 - 66,920,063 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1466,911,170 - 66,921,023 (+)EnsemblGRCm38mm10GRCm38
MGSCv371467,530,045 - 67,538,898 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361465,869,515 - 65,874,167 (+)NCBIMGSCv36mm8
Celera1464,664,973 - 64,673,798 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.6NCBI
PNMA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38826,504,701 - 26,513,872 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl826,504,701 - 26,514,092 (-)EnsemblGRCh38hg38GRCh38
GRCh37826,362,217 - 26,371,388 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36826,418,113 - 26,427,400 (-)NCBINCBI36Build 36hg18NCBI36
Celera825,324,618 - 25,333,902 (-)NCBICelera
Cytogenetic Map8p21.2NCBI
HuRef824,907,036 - 24,916,314 (-)NCBIHuRef
CHM1_1826,563,803 - 26,573,090 (-)NCBICHM1_1
T2T-CHM13v2.0826,781,276 - 26,790,451 (-)NCBIT2T-CHM13v2.0
Pnma2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81545,287,445 - 45,296,340 (+)NCBIGRCr8
mRatBN7.21541,111,942 - 41,119,649 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1541,112,009 - 41,121,427 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1542,977,486 - 42,985,039 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01544,127,698 - 44,135,253 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01542,572,270 - 42,579,929 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01543,581,874 - 43,589,680 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1543,582,020 - 43,589,680 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01548,006,292 - 48,014,067 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41546,452,913 - 46,460,573 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11546,473,585 - 46,474,680 (+)NCBI
Celera1540,779,534 - 40,786,898 (+)NCBICelera
Cytogenetic Map15p12NCBI
Pnma2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540349,183,280 - 49,184,855 (-)NCBIChiLan1.0ChiLan1.0
PNMA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2745,038,107 - 45,047,393 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1820,752,210 - 20,761,495 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0825,777,591 - 25,786,877 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1822,684,517 - 22,693,903 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl822,687,494 - 22,688,588 (-)Ensemblpanpan1.1panPan2
PNMA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12531,038,519 - 31,045,874 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2531,042,477 - 31,043,571 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2531,626,722 - 31,634,100 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02531,238,188 - 31,245,570 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2531,238,204 - 31,245,591 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12531,172,868 - 31,180,236 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02531,043,957 - 31,051,322 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02531,210,416 - 31,217,798 (+)NCBIUU_Cfam_GSD_1.0
Pnma2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049439,170,548 - 9,176,853 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936757423,220 - 429,447 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PNMA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1410,422,331 - 10,428,389 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11410,422,325 - 10,428,389 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21411,587,498 - 11,593,567 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PNMA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1824,620,551 - 24,625,695 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl824,619,441 - 24,620,535 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605217,533,473 - 17,542,911 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pnma2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475821,350,675 - 21,355,715 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475821,322,368 - 21,355,720 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pnma2
589 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1559
Count of miRNA genes:605
Interacting mature miRNAs:755
Transcripts:ENSMUST00000089236, ENSMUST00000122431, ENSMUST00000165831, ENSMUST00000168010
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145608238190082509Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145654674590546941Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1458179640101859473Mouse
11039527Ccc2_mcolitis susceptibility in the Collaborative Cross 2 (mouse)145991861294138217Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146239746096397680Mouse
10043888Cia51_mcollagen induced arthritis QTL 51 (mouse)Not determined146610389368785736Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000089236   ⟹   ENSMUSP00000086646
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1467,148,619 - 67,158,472 (+)Ensembl
GRCm38.p6 Ensembl1466,911,170 - 66,921,023 (+)Ensembl
RefSeq Acc Id: ENSMUST00000122431   ⟹   ENSMUSP00000112629
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1467,148,657 - 67,156,264 (+)Ensembl
GRCm38.p6 Ensembl1466,911,208 - 66,918,815 (+)Ensembl
RefSeq Acc Id: ENSMUST00000165831
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1467,151,765 - 67,153,484 (+)Ensembl
GRCm38.p6 Ensembl1466,914,316 - 66,916,035 (+)Ensembl
RefSeq Acc Id: ENSMUST00000168010
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1467,148,691 - 67,152,175 (+)Ensembl
GRCm38.p6 Ensembl1466,911,242 - 66,914,726 (+)Ensembl
RefSeq Acc Id: NM_175498   ⟹   NP_780707
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391467,148,657 - 67,157,510 (+)NCBI
GRCm381466,911,208 - 66,920,061 (+)NCBI
MGSCv371467,530,045 - 67,538,898 (+)RGD
Celera1464,664,973 - 64,673,798 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006518989   ⟹   XP_006519052
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391467,147,635 - 67,157,512 (+)NCBI
GRCm381466,911,111 - 66,920,063 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006518990   ⟹   XP_006519053
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391467,139,038 - 67,157,512 (+)NCBI
GRCm381466,901,589 - 66,920,063 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_780707   ⟸   NM_175498
- UniProtKB: Q8BHK0 (UniProtKB/Swiss-Prot),   Q5DU13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519053   ⟸   XM_006518990
- Peptide Label: isoform X1
- UniProtKB: Q8BHK0 (UniProtKB/Swiss-Prot),   Q5DU13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519052   ⟸   XM_006518989
- Peptide Label: isoform X1
- UniProtKB: Q8BHK0 (UniProtKB/Swiss-Prot),   Q5DU13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000086646   ⟸   ENSMUST00000089236
RefSeq Acc Id: ENSMUSP00000112629   ⟸   ENSMUST00000122431
Protein Domains
Paraneoplastic antigen Ma-like C-terminal   Paraneoplastic antigen Ma-like N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BHK0-F1-model_v2 AlphaFold Q8BHK0 1-365 view protein structure

Promoters
RGD ID:8682806
Promoter ID:EPDNEW_M19434
Type:multiple initiation site
Name:Pnma2_1
Description:Mus musculus paraneoplastic antigen MA2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381466,911,237 - 66,911,297EPDNEW
RGD ID:6825276
Promoter ID:MM_KWN:17289
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000089236
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361467,528,851 - 67,529,351 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444129 AgrOrtholog
Ensembl Genes ENSMUSG00000046204 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000089236 ENTREZGENE
  ENSMUST00000089236.11 UniProtKB/Swiss-Prot
  ENSMUST00000122431.3 UniProtKB/Swiss-Prot
InterPro PNMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PNMA_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PNMA_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:239157 UniProtKB/Swiss-Prot
MGD MGI:2444129 ENTREZGENE
NCBI Gene 239157 ENTREZGENE
PANTHER PTHR23095 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23095:SF16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PNMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PNMA_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pnma2 PhenoGen
UniProt PNMA2_MOUSE UniProtKB/Swiss-Prot
  Q5DU13 ENTREZGENE, UniProtKB/TrEMBL
  Q8BHK0 ENTREZGENE