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Gene: EIF3G (eukaryotic translation initiation factor 3 subunit G) Homo sapiens
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Symbol: EIF3G
Name: eukaryotic translation initiation factor 3 subunit G
Description: This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy. [provided by RefSeq, Jul 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: eIF-3 RNA-binding subunit; eIF-3-delta; eIF3 p42; eIF3 p44; eIF3-delta; EIF3-P42; eIF3-p44; EIF3S4; eukaryotic translation initiation factor 3 RNA-binding subunit; eukaryotic translation initiation factor 3 subunit 4; eukaryotic translation initiation factor 3 subunit p42; eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD); eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; eukaryotic translation initiation factor 3, subunit G
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,115,014 - 10,119,899 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,225,690 - 10,230,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,086,690 - 10,091,599 (-)NCBINCBI36hg18NCBI36
Build 341910,086,690 - 10,091,585NCBI
Celera1910,121,181 - 10,126,038 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,806,336 - 9,811,241 (-)NCBIHuRef
CHM1_11910,225,972 - 10,230,857 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on EIF3G
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316234
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.