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Gene: Pigt (phosphatidylinositol glycan anchor biosynthesis, class T) Mus musculus
Symbol: Pigt
Name: phosphatidylinositol glycan anchor biosynthesis, class T
Description: Contributes to GPI-anchor transamidase activity. Involved in attachment of GPI anchor to protein; neuron apoptotic process; and neuron differentiation. Localizes to the GPI-anchor transamidase complex and cytoplasmic vesicle. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 3 and paroxysmal nocturnal hemoglobinuria. Orthologous to human PIGT (phosphatidylinositol glycan anchor biosynthesis class T); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2510012P17Rik; 4930534E15Rik; CGI-06; GPI transamidase component PIG-T; NDAP; Ndap7; neuronal development-associated protein 7; phosphatidylinositol glycan, class T; phosphatidylinositol-glycan biosynthesis class T protein
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382164,497,090 - 164,508,301 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372164,323,025 - 164,333,801 (+)NCBIGRCm37mm9NCBIm37
MGSCv362164,188,770 - 164,198,971 (+)NCBImm8
Celera2170,434,562 - 170,445,144 (+)NCBICelera
Cytogenetic Map2 H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pigt
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316181
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.