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Gene: OLIG2 (oligodendrocyte transcription factor 2) Homo sapiens
Symbol: OLIG2
Name: oligodendrocyte transcription factor 2
RGD ID: 1316088
Description: Exhibits sequence-specific double-stranded DNA binding activity. Predicted to be involved in neuron differentiation; regulation of transcription by RNA polymerase II; and spinal cord oligodendrocyte cell differentiation. Predicted to localize to nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic domain, helix-loop-helix protein, class B, 1; BHLHB1; bHLHe19; class B basic helix-loop-helix protein 1; class E basic helix-loop-helix protein 19; human protein kinase C-binding protein RACK17; OLIGO2; oligodendrocyte lineage transcription factor 2; oligodendrocyte-specific bHLH transcription factor 2; PRKCBP2; protein kinase C binding protein 2; protein kinase C-binding protein 2; protein kinase C-binding protein RACK17; RACK17
Mus musculus (house mouse) : Olig2 (oligodendrocyte transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Olig2 (oligodendrocyte transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Olig2 (oligodendrocyte transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : OLIG2 (oligodendrocyte transcription factor 2)
Canis lupus familiaris (dog) : OLIG2 (oligodendrocyte transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Olig2 (oligodendrocyte transcription factor 2)
Sus scrofa (pig) : OLIG2 (oligodendrocyte transcription factor 2)
Chlorocebus sabaeus (African green monkey) : OLIG2 (oligodendrocyte transcription factor 2)
Heterocephalus glaber (naked mole-rat) : Olig2 (oligodendrocyte transcription factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2133,025,935 - 33,029,196 (+)EnsemblGRCh38hg38GRCh38
GRCh382133,025,935 - 33,029,196 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372134,398,216 - 34,401,504 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,320,109 - 33,323,370 (+)NCBINCBI36hg18NCBI36
Build 342133,320,162 - 33,323,371NCBI
Celera2119,583,840 - 19,587,101 (+)NCBI
Cytogenetic Map21q22.11NCBI
HuRef2119,809,438 - 19,812,730 (+)NCBIHuRef
CHM1_12133,960,322 - 33,963,610 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on OLIG2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316088
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.