Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1-naphthyl isothiocyanate | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in increased expression of TMEM169 mRNA | CTD | PMID:30723492 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM169 mRNA | CTD | PMID:21570461 | 2-methylcholine | affects expression | ISO | TMEM169 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of TMEM169 mRNA | CTD | PMID:21179406 | 6-propyl-2-thiouracil | decreases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of TMEM169 mRNA | CTD | PMID:30047161 | acetamide | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | acetamide results in increased expression of TMEM169 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of TMEM169 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | TMEM169 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TMEM169 gene | CTD | PMID:27153756 | aflatoxin B1 | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of TMEM169 mRNA | CTD | PMID:27153756 | amitrole | decreases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of TMEM169 mRNA | CTD | PMID:30047161 | aristolochic acid A | increases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TMEM169 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | increases methylation | ISO | TMEM169 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TMEM169 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TMEM169 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | decreases methylation | ISO | TMEM169 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TMEM169 5' UTR | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TMEM169 mRNA | CTD | PMID:31163220 | bisphenol A | decreases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TMEM169 mRNA | CTD | PMID:25181051 | caffeine | decreases phosphorylation | ISO | TMEM169 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of TMEM169 protein | CTD | PMID:35688186 | copper atom | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of TMEM169 mRNA | CTD | PMID:26033743 | copper(0) | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of TMEM169 mRNA | CTD | PMID:26033743 | Cuprizon | decreases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of TMEM169 mRNA | CTD | PMID:26577399 | dorsomorphin | multiple interactions | ISO | TMEM169 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of TMEM169 mRNA | CTD | PMID:29391264 | entinostat | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | entinostat results in decreased expression of TMEM169 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | TMEM169 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TMEM169 mRNA | CTD | PMID:27188386 | ethanol | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Ethanol results in increased expression of TMEM169 mRNA | CTD | PMID:31078653 | folic acid | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of TMEM169 mRNA | CTD | PMID:21867686 | furan | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | furan results in increased expression of TMEM169 mRNA | CTD | PMID:25539665 | gentamycin | decreases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of TMEM169 mRNA | CTD | PMID:33387578 | leflunomide | increases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | leflunomide results in increased expression of TMEM169 mRNA | CTD | PMID:28988120 | lipopolysaccharide | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of TMEM169 mRNA | CTD | PMID:35811015 | lipopolysaccharide | multiple interactions | ISO | TMEM169 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | methimazole | decreases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of TMEM169 mRNA | CTD | PMID:30047161 | methylmercury chloride | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of TMEM169 mRNA | CTD | PMID:28001369 | panobinostat | multiple interactions | ISO | TMEM169 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TMEM169 mRNA | CTD | PMID:27188386 | panobinostat | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of TMEM169 mRNA | CTD | PMID:26272509 | paracetamol | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of TMEM169 mRNA | CTD | PMID:33387578 | perfluorohexanesulfonic acid | increases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in increased expression of TMEM169 mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of TMEM169 mRNA | CTD | PMID:36331819 | phenylmercury acetate | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of TMEM169 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | TMEM169 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TMEM169 mRNA | CTD | PMID:27188386 | resorcinol | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | resorcinol results in decreased expression of TMEM169 mRNA | CTD | PMID:22623647 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | TMEM169 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | TMEM169 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of TMEM169 mRNA | CTD | PMID:23806026 and PMID:25895662 | sodium arsenite | affects expression | ISO | TMEM169 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of TMEM169 mRNA | CTD | PMID:29319823 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of TMEM169 mRNA | CTD | PMID:37682722 | sulfadimethoxine | decreases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of TMEM169 mRNA | CTD | PMID:30047161 | temozolomide | increases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of TMEM169 mRNA | CTD | PMID:31758290 | trichloroethene | increases expression | ISO | Tmem169 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of TMEM169 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TMEM169 mRNA | CTD | PMID:24935251 | trichostatin A | affects expression | ISO | TMEM169 (Homo sapiens) | 6480464 | trichostatin A affects the expression of TMEM169 mRNA | CTD | PMID:28542535 | trichostatin A | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of TMEM169 mRNA | CTD | PMID:24935251 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of TMEM169 mRNA | CTD | PMID:33045310 | urethane | increases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Urethane results in increased expression of TMEM169 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of TMEM169 mRNA | CTD | PMID:17963808 | valproic acid | affects expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TMEM169 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TMEM169 mRNA | CTD | PMID:24935251 and PMID:29154799 | valproic acid | decreases expression | ISO | TMEM169 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TMEM169 mRNA | CTD | PMID:26272509 and PMID:28001369 | valproic acid | multiple interactions | ISO | TMEM169 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TMEM169 mRNA | CTD | PMID:27188386 | |