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Gene: Plscr3 (phospholipid scramblase 3) Mus musculus
Symbol: Plscr3
Name: phospholipid scramblase 3
Description: Predicted to have calcium-dependent protein binding activity and phospholipid scramblase activity. Involved in cellular response to lipopolysaccharide; cholesterol homeostasis; and glucose homeostasis. Predicted to colocalize with the mitochondrion. Used to study obesity. Orthologous to human PLSCR3 (phospholipid scramblase 3); PARTICIPATES IN cardiolipin metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[b]fluoranthene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2210403O21Rik; 2610037N06Rik; Ca 2+ dependent phospholipid scramblase 3; ca(2+)-dependent phospholipid scramblase 3; ESTM3; PL scramblase 3; X83310
Homo sapiens (human) : PLSCR3 (phospholipid scramblase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Plscr3 (phospholipid scramblase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plscr3 (phospholipid scramblase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PLSCR3 (phospholipid scramblase 3)
Canis lupus familiaris (dog) : PLSCR3 (phospholipid scramblase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plscr3 (phospholipid scramblase 3)
Sus scrofa (pig) : PLSCR3 (phospholipid scramblase 3)
Chlorocebus sabaeus (African green monkey) : PLSCR3 (phospholipid scramblase 3)
Heterocephalus glaber (naked mole-rat) : Plscr3 (phospholipid scramblase 3)
more info ...
Related Pseudogenes: Gm18361  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1169,846,376 - 69,852,058 (+)EnsemblGRCm38mm10GRCm38
GRCm381169,846,372 - 69,852,058 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371169,659,874 - 69,665,560 (+)NCBIGRCm37mm9NCBIm37
MGSCv361169,662,871 - 69,668,253 (+)NCBImm8
MGSCv361170,430,783 - 70,436,165 (+)NCBImm8
Cytogenetic Map11B3NCBI
cM Map1142.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Plscr3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315961
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.