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Gene: INSM2 (INSM transcriptional repressor 2) Homo sapiens
Symbol: INSM2
Name: INSM transcriptional repressor 2
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific. Predicted to be involved in negative regulation of transcription by RNA polymerase II; neuron differentiation; and regulation of cell cycle process. Predicted to localize to the nucleus and transcriptional repressor complex; INTERACTS WITH 2-methylcholine; 8-bromo-3',5'-cyclic AMP; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IA-6; IA6; INSM2 variant 1; insulinoma-associated 2; insulinoma-associated protein 2; insulinoma-associated protein IA-6; mlt1; zinc finger protein IA-6
Mus musculus (house mouse) : Insm2 (insulinoma-associated 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Insm2 (INSM transcriptional repressor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Insm2 (INSM transcriptional repressor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : INSM2 (INSM transcriptional repressor 2)
Canis lupus familiaris (dog) : INSM2 (INSM transcriptional repressor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Insm2 (INSM transcriptional repressor 2)
Sus scrofa (pig) : INSM2 (INSM transcriptional repressor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1435,534,164 - 35,537,054 (+)Ensembl
GRCh381435,534,164 - 35,537,054 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371436,003,248 - 36,006,260 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361435,072,999 - 35,076,011 (+)NCBINCBI36hg18NCBI36
Build 341435,072,998 - 35,076,011NCBI
Celera1415,867,108 - 15,870,120 (+)NCBI
Cytogenetic Map14q13.2NCBI
HuRef1416,117,138 - 16,120,150 (+)NCBIHuRef
CHM1_11436,002,929 - 36,005,941 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on INSM2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315853
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.