Spns3 (spinster homolog 3) - Rat Genome Database
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Gene: Spns3 (spinster homolog 3) Mus musculus
Analyze
Symbol: Spns3
Name: spinster homolog 3
RGD ID: 1315769
MGI Page MGI
Description: Orthologous to human SPNS3 (sphingolipid transporter 3 (putative)); INTERACTS WITH 1,2-dimethylhydrazine; all-trans-retinoic acid; buta-1,3-diene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 9830002I17Rik; protein spinster homolog 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,388,979 - 72,441,334 (-)NCBIGRCm39mm39
GRCm39 Ensembl1172,385,745 - 72,441,332 (-)Ensembl
GRCm381172,498,153 - 72,550,509 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,494,919 - 72,550,506 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,311,658 - 72,363,748 (-)NCBIGRCm37mm9NCBIm37
MGSCv361172,314,351 - 72,366,441 (-)NCBImm8
Celera1180,018,322 - 80,070,509 (-)NCBICelera
Cytogenetic Map11B4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17714910  


Genomics

Comparative Map Data
Spns3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,388,979 - 72,441,334 (-)NCBIGRCm39mm39
GRCm39 Ensembl1172,385,745 - 72,441,332 (-)Ensembl
GRCm381172,498,153 - 72,550,509 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,494,919 - 72,550,506 (-)EnsemblGRCm38mm10GRCm38
MGSCv371172,311,658 - 72,363,748 (-)NCBIGRCm37mm9NCBIm37
MGSCv361172,314,351 - 72,366,441 (-)NCBImm8
Celera1180,018,322 - 80,070,509 (-)NCBICelera
Cytogenetic Map11B4NCBI
SPNS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl174,433,940 - 4,488,208 (+)EnsemblGRCh38hg38GRCh38
GRCh38174,433,940 - 4,488,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37174,337,235 - 4,391,499 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36174,283,968 - 4,338,248 (+)NCBINCBI36hg18NCBI36
Celera174,349,747 - 4,403,640 (+)NCBI
Cytogenetic Map17p13.2NCBI
HuRef174,227,024 - 4,280,745 (+)NCBIHuRef
CHM1_1174,345,971 - 4,400,060 (+)NCBICHM1_1
Spns3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21057,114,247 - 57,169,056 (-)NCBI
Rnor_6.0 Ensembl1059,057,789 - 59,112,788 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01059,056,460 - 59,113,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01058,792,618 - 58,851,321 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41059,382,792 - 59,438,400 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1056,241,019 - 56,293,466 (-)NCBICelera
Cytogenetic Map10q24NCBI
Spns3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546712,447,232 - 12,496,874 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546712,447,232 - 12,496,874 (-)NCBIChiLan1.0ChiLan1.0
SPNS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1174,482,672 - 4,536,703 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl174,482,672 - 4,536,393 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0174,488,490 - 4,543,846 (+)NCBIMhudiblu_PPA_v0panPan3
SPNS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl530,464,513 - 30,526,882 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1530,464,288 - 30,493,609 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Spns3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366771,007,776 - 1,050,870 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPNS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1250,388,375 - 50,446,297 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11250,388,973 - 50,445,297 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21252,389,047 - 52,445,102 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPNS3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,914,020 - 3,967,595 (+)NCBI
Spns3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247867,010,136 - 7,060,442 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116910000072600000Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116910000072600000Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116910000072600000Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116910000072600000Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116910000072600000Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116910000072600000Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116910000072600000Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116910000072600000Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116910000072600000Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116910000072600000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:628
Count of miRNA genes:288
Interacting mature miRNAs:341
Transcripts:ENSMUST00000021154, ENSMUST00000092940, ENSMUST00000155774
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000021154   ⟹   ENSMUSP00000021154
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1172,498,160 - 72,550,301 (-)Ensembl
RefSeq Acc Id: ENSMUST00000092940   ⟹   ENSMUSP00000090617
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1172,498,155 - 72,550,506 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155774
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1172,494,919 - 72,502,443 (-)Ensembl
RefSeq Acc Id: NM_029932   ⟹   NP_084208
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391172,388,982 - 72,441,072 (-)NCBI
GRCm381172,498,156 - 72,550,246 (-)NCBI
MGSCv371172,311,658 - 72,363,748 (-)RGD
Celera1180,018,322 - 80,070,509 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534486   ⟹   XP_006534549
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391172,388,979 - 72,441,327 (-)NCBI
GRCm381172,498,153 - 72,550,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006534488   ⟹   XP_006534551
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391172,388,979 - 72,428,880 (-)NCBI
GRCm381172,498,153 - 72,538,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249311   ⟹   XP_011247613
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391172,388,979 - 72,436,779 (-)NCBI
GRCm381172,498,153 - 72,545,953 (-)NCBI
Sequence:
RefSeq Acc Id: XR_388556
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391172,388,979 - 72,441,327 (-)NCBI
GRCm381172,498,153 - 72,550,501 (-)NCBI
Sequence:
RefSeq Acc Id: XR_388557
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391172,388,979 - 72,441,334 (-)NCBI
GRCm381172,498,153 - 72,550,509 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_084208   ⟸   NM_029932
- UniProtKB: Q9D232 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534549   ⟸   XM_006534486
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006534551   ⟸   XM_006534488
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011247613   ⟸   XM_011249311
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000090617   ⟸   ENSMUST00000092940
RefSeq Acc Id: ENSMUSP00000021154   ⟸   ENSMUST00000021154

Promoters
RGD ID:6822212
Promoter ID:MM_KWN:8330
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung,   Spleen
Transcripts:OTTMUST00000018371,   OTTMUST00000018372
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361172,363,631 - 72,364,131 (-)MPROMDB
RGD ID:8675444
Promoter ID:EPDNEW_M15753
Type:initiation region
Name:Spns3_1
Description:Mus musculus spinster homolog 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381172,550,238 - 72,550,298EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1924827 AgrOrtholog
Ensembl Genes ENSMUSG00000020798 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000021154 UniProtKB/Swiss-Prot
  ENSMUSP00000090617 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000021154 UniProtKB/Swiss-Prot
  ENSMUST00000092940 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro MFS UniProtKB/Swiss-Prot
  MFS_dom UniProtKB/Swiss-Prot
  MFS_trans_sf UniProtKB/Swiss-Prot
KEGG Report mmu:77577 UniProtKB/Swiss-Prot
MGD MGI:1924827 ENTREZGENE
NCBI Gene 77577 ENTREZGENE
Pfam MFS_1 UniProtKB/Swiss-Prot
PhenoGen Spns3 PhenoGen
PROSITE MFS UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot
UniProt Q3TN98_MOUSE UniProtKB/TrEMBL
  Q9D232 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2RX04 UniProtKB/Swiss-Prot
  Q3U0X5 UniProtKB/Swiss-Prot
  Q8BYA9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-17 Spns3  spinster homolog 3  Spns3  spinster homolog 3 (Drosophila)  Symbol and/or name change 5135510 APPROVED