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Gene: RFC3 (replication factor C subunit 3) Homo sapiens
Symbol: RFC3
Name: replication factor C subunit 3
Description: Contributes to DNA clamp loader activity and single-stranded DNA helicase activity. Involved in DNA replication; positive regulation of DNA-directed DNA polymerase activity; and response to organophosphorus. Localizes to the Ctf18 RFC-like complex and DNA replication factor C complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A1 38 kDa subunit; activator 1 38 kDa subunit; activator 1 subunit 3; MGC5276; replication factor C (activator 1) 3, 38kDa; replication factor C 38 kDa subunit; RF-C 38 kDa subunit; RFC, 38 kD subunit; RFC38
Mus musculus (house mouse) : Rfc3 (replication factor C (activator 1) 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rfc3 (replication factor C subunit 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rfc3 (replication factor C subunit 3)
Pan paniscus (bonobo/pygmy chimpanzee) : RFC3 (replication factor C subunit 3)
Canis lupus familiaris (dog) : RFC3 (replication factor C subunit 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rfc3 (replication factor C subunit 3)
Sus scrofa (pig) : RFC3 (replication factor C subunit 3)
more info ...
Related Pseudogenes: RFC3P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1333,818,069 - 33,966,558 (+)Ensembl
GRCh381333,818,069 - 33,973,946 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371334,392,206 - 34,540,695 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361333,290,206 - 33,438,695 (+)NCBINCBI36hg18NCBI36
Build 341333,290,233 - 33,438,695NCBI
Celera1315,458,790 - 15,607,255 (+)NCBI
Cytogenetic Map13q13.2NCBI
HuRef1315,203,964 - 15,352,421 (+)NCBIHuRef
CHM1_11334,360,142 - 34,508,658 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RFC3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315670
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.