Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of S100A16 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of S100A16 mRNA] | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of S100A16 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of S100A16 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of S100A16 mRNA | CTD | PMID:17555576 | 17beta-estradiol | affects expression | ISO | S100A16 (Homo sapiens) | 6480464 | Estradiol affects the expression of S100A16 mRNA | CTD | PMID:22574217 | 17beta-estradiol | increases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of S100A16 mRNA | CTD | PMID:32145629 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Polyphenols co-treated with Estradiol] results in increased expression of S100A16 mRNA | CTD | PMID:30077407 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of S100A16 mRNA | CTD | PMID:30077407 | 17beta-estradiol | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of S100A16 mRNA | CTD | PMID:23019147 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of S100A16 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of S100A16 protein | CTD | PMID:37788135 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of S100A16 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of S100A16 mRNA | CTD | PMID:32109520 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of S100A16 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,3-dimethoxynaphthalene-1,4-dione | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:37788135 | 2,4-dinitrotoluene | affects expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of S100A16 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of S100A16 mRNA | CTD | PMID:21346803 | 3,7-dihydropurine-6-thione | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of S100A16 mRNA | CTD | PMID:23358152 | 4,4'-sulfonyldiphenol | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of S100A16 protein | CTD | PMID:34186270 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of S100A16 mRNA | CTD | PMID:28973697 | aflatoxin B1 | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of S100A16 mRNA | CTD | PMID:22100608 | all-trans-retinoic acid | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of S100A16 mRNA | CTD | PMID:23830798 | amphetamine | increases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Amphetamine results in increased expression of S100A16 mRNA | CTD | PMID:30779732 | antirheumatic drug | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of S100A16 mRNA | CTD | PMID:24449571 | Aroclor 1254 | increases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of S100A16 mRNA | CTD | PMID:23650126 | atrazine | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Atrazine results in increased expression of S100A16 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of S100A16 mRNA | CTD | PMID:21632981 more ... | benzo[a]pyrene | affects methylation | ISO | S100A16 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of S100A16 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | S100A16 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of S100A16 5' UTR | CTD | PMID:27901495 | Benzo[k]fluoranthene | decreases expression | EXP | | 6480464 | benzo(k)fluoranthene results in decreased expression of S100A16 mRNA | CTD | PMID:26377693 | bis(2-ethylhexyl) phthalate | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of S100A16 mRNA | CTD | PMID:31163220 | bisphenol A | increases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of S100A16 mRNA | CTD | PMID:25181051 and PMID:32145629 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of S100A16 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of S100A16 mRNA | CTD | PMID:35598803 | bisphenol A | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of S100A16 mRNA | CTD | PMID:33296240 and PMID:34947998 | bisphenol A | affects expression | ISO | S100A16 (Homo sapiens) | 6480464 | bisphenol A affects the expression of S100A16 mRNA | CTD | PMID:30903817 | bisphenol A | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of S100A16 mRNA | CTD | PMID:29275510 | carbamazepine | affects expression | ISO | S100A16 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of S100A16 mRNA | CTD | PMID:25979313 | chlordecone | increases expression | EXP | | 6480464 | Chlordecone results in increased expression of S100A16 mRNA | CTD | PMID:33711761 | chloropicrin | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of S100A16 mRNA | CTD | PMID:26352163 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of S100A16 mRNA | CTD | PMID:37019170 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of S100A16 mRNA | CTD | PMID:28472532 | copper(II) sulfate | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of S100A16 mRNA | CTD | PMID:19549813 | crocidolite asbestos | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in increased expression of S100A16 mRNA | CTD | PMID:29523930 | cyclosporin A | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of S100A16 mRNA | CTD | PMID:25562108 | disodium selenite | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of S100A16 mRNA | CTD | PMID:18175754 | diuron | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Diuron results in decreased expression of S100A16 mRNA | CTD | PMID:21551480 | doxorubicin | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of S100A16 mRNA | CTD | PMID:29803840 | fluoranthene | multiple interactions | EXP | | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of S100A16 mRNA | CTD | PMID:28329830 | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of S100A16 mRNA] | CTD | PMID:22206623 | genistein | multiple interactions | ISO | S100A16 (Homo sapiens) | 6480464 | ESR2 promotes the reaction [Genistein results in decreased expression of S100A16 protein] | CTD | PMID:20884965 | genistein | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Genistein results in decreased expression of S100A16 protein | CTD | PMID:20884965 | gentamycin | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of S100A16 mRNA | CTD | PMID:33387578 | ivermectin | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of S100A16 protein | CTD | PMID:32959892 | lasalocid | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Lasalocid results in increased expression of S100A16 protein | CTD | PMID:37788135 | lead(0) | affects expression | ISO | S100A16 (Homo sapiens) | 6480464 | Lead affects the expression of S100A16 mRNA | CTD | PMID:28903495 | manganese(II) chloride | increases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | manganese chloride results in increased expression of S100A16 mRNA | CTD | PMID:28801915 | mercaptopurine | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of S100A16 mRNA | CTD | PMID:23358152 | N-nitrosodiethylamine | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Diethylnitrosamine results in increased expression of S100A16 mRNA | CTD | PMID:21527772 | N-Nitrosopyrrolidine | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in increased expression of S100A16 mRNA | CTD | PMID:32234424 | oxaliplatin | multiple interactions | ISO | S100a16 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of S100A16 mRNA | CTD | PMID:25729387 | oxaliplatin | increases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | oxaliplatin results in increased expression of S100A16 mRNA | CTD | PMID:25729387 | paracetamol | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of S100A16 mRNA | CTD | PMID:33387578 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of S100A16 mRNA | CTD | PMID:23892564 | phenobarbital | affects expression | ISO | S100A16 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of S100A16 mRNA | CTD | PMID:19159669 | pirinixic acid | multiple interactions | ISO | S100A16 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of S100A16 mRNA | CTD | PMID:19710929 | purine-6-thiol | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Mercaptopurine results in decreased expression of S100A16 mRNA | CTD | PMID:23358152 | quercetin | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Quercetin results in increased expression of S100A16 mRNA | CTD | PMID:21632981 | serpentine asbestos | decreases methylation | ISO | S100A16 (Homo sapiens) | 6480464 | Asbestos and Serpentine results in decreased methylation of S100A16 5' UTR | CTD | PMID:29523930 | sevoflurane | increases methylation | EXP | | 6480464 | Sevoflurane results in increased methylation of S100A16 mRNA | CTD | PMID:35249202 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of S100A16 protein | CTD | PMID:29044176 | sunitinib | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of S100A16 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of S100A16 mRNA | CTD | PMID:17555576 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of S100A16 mRNA | CTD | PMID:17484886 | topotecan | increases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Topotecan results in increased expression of S100A16 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | ISO | S100a16 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of S100A16 mRNA | CTD | PMID:25729387 | trichloroethene | decreases expression | ISO | S100a16 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of S100A16 mRNA | CTD | PMID:33387578 | trimellitic anhydride | decreases expression | EXP | | 6480464 | trimellitic anhydride results in decreased expression of S100A16 mRNA | CTD | PMID:19042947 | tris(2-butoxyethyl) phosphate | affects expression | ISO | S100A16 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of S100A16 mRNA | CTD | PMID:29024780 | valproic acid | decreases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of S100A16 mRNA | CTD | PMID:29154799 | valproic acid | increases expression | ISO | S100A16 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of S100A16 mRNA | CTD | PMID:23179753 | |