Gene: Rbmxl1 (RNA binding motif protein, X-linked like-1) Mus musculus
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Symbol:
Rbmxl1
Name:
RNA binding motif protein, X-linked like-1
RGD ID:
1315547
MGI Page
MGI
Description:
Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Is expressed in central nervous system and sensory organ. Orthologous to human RBMXL1 (RBMX like 1); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
heterogeneous nuclear ribonucleoprotein G; heterogeneous nuclear ribonucleoprotein G (hnRNP G); heterogeneous nuclear ribonucleoprotein G-like 1; Hn; hnRNP G; Hnrpg; MGC102184; Rbmx; Rbmxrt; RNA binding motif protein, X chromosome retrogene; RNA binding motif protein, X linked-like-1; RNA binding motif protein, X-linked-like-1; RNA-binding motif protein, X chromosome
RGD Orthologs
Alliance Genes
More Info
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
RBMXL1 (RBMX like 1)
HGNC
Ensembl, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):
Rbmxl1 (RBMX like 1)
HGNC
Treefam, OrthoMCL, OrthoDB
Pan paniscus (bonobo/pygmy chimpanzee):
RBMXL1 (RBMX like 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
RBMXL1 (RBMX like 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
RBMX (RNA binding motif protein X-linked)
HGNC
Ensembl, OrthoDB, Panther, Treefam
Homo sapiens (human):
RBMY1B (RNA binding motif protein Y-linked family 1 member B)
HGNC
Panther, Treefam
Homo sapiens (human):
RBMY1A1 (RNA binding motif protein Y-linked family 1 member A1)
HGNC
Treefam
Homo sapiens (human):
RBMY1E (RNA binding motif protein Y-linked family 1 member E)
HGNC
Treefam
Homo sapiens (human):
RBMY1J (RNA binding motif protein Y-linked family 1 member J)
HGNC
Treefam
Homo sapiens (human):
RBMY1D (RNA binding motif protein Y-linked family 1 member D)
HGNC
Treefam
Homo sapiens (human):
RBMY1F (RNA binding motif protein Y-linked family 1 member F)
HGNC
Treefam
Homo sapiens (human):
RBMXL2 (RBMX like 2)
HGNC
OrthoDB
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Rbmxl1 (RBMX like 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Rattus norvegicus (Norway rat):
Rbmxl1b (RNA binding motif protein, X-linked-like 1B)
Alliance
DIOPT (OrthoFinder|PANTHER|PhylomeDB)
Homo sapiens (human):
RBMXL1 (RBMX like 1)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
rbmx (RNA binding motif protein X-linked)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|TreeFam)
Related Pseudogenes:
Gm7324
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 8 79,231,898 - 79,235,557 (-) NCBI GRCm39 mm39 GRCm38 8 78,505,269 - 78,508,928 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 8 78,505,269 - 78,508,898 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 8 81,029,168 - 81,032,827 (-) NCBI GRCm37 mm9 NCBIm37 MGSCv36 8 81,401,341 - 81,405,000 (-) NCBI mm8 Celera 8 82,781,894 - 82,785,553 (-) NCBI Celera Cytogenetic Map 8 C1 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
1,2-dichloroethane increases expression EXP 6480464 ethylene dichloride results in increased expression of RBMXL1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions EXP 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RBMXL1 mRNA CTD PMID:22206623 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of RBMXL1 mRNA CTD PMID:15598610 2,3',4,4',5-Pentachlorobiphenyl affects expression EXP 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RBMXL1 mRNA CTD PMID:19465110 aflatoxin B1 decreases methylation ISO RGD:1603234 6480464 Aflatoxin B1 results in decreased methylation of RBMXL1 gene CTD PMID:27153756 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl 54% Chlorine results in decreased expression of RBMXL1 mRNA CTD PMID:23650126 benzo[a]pyrene multiple interactions EXP 6480464 AHR protein affects the reaction [Benzoapyrene affects the expression of RBMY1A1 mRNA] CTD PMID:22228805 benzo[a]pyrene affects methylation ISO RGD:1603234 6480464 Benzoapyrene affects the methylation of RBMXL1 5' UTR CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzoapyrene results in increased expression of RBMY1A1 mRNA CTD PMID:22228805 bisphenol A decreases expression ISO RGD:1306751 6480464 bisphenol A results in decreased expression of RBMXL1 mRNA CTD PMID:30816183 bisphenol A increases expression ISO RGD:1306751 6480464 bisphenol A results in increased expression of RBMXL1 mRNA CTD PMID:25181051 calcitriol decreases expression ISO RGD:1603234 6480464 Calcitriol results in decreased expression of RBMXL1 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1603234 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of RBMXL1 mRNA CTD PMID:21592394 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon results in increased expression of RBMXL1 mRNA CTD PMID:25554681 cyclosporin A decreases expression ISO RGD:1603234 6480464 Cyclosporine results in decreased expression of RBMXL1 mRNA CTD PMID:25562108 doxorubicin decreases expression ISO RGD:1603234 6480464 Doxorubicin results in decreased expression of RBMXL1 mRNA CTD PMID:29803840 enzyme inhibitor multiple interactions ISO RGD:1603234 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RBMXL1 protein CTD PMID:23301498 flutamide increases expression ISO RGD:1306751 6480464 Flutamide results in increased expression of RBMXL1 mRNA CTD PMID:24136188 folic acid multiple interactions EXP 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RBMXL1 mRNA CTD PMID:22206623 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of RBMXL1 mRNA CTD PMID:25629700 gentamycin increases expression ISO RGD:1306751 6480464 Gentamicins results in increased expression of RBMXL1 mRNA CTD PMID:22061828 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of RBMXL1 protein CTD PMID:26558463 N-nitrosodiethylamine multiple interactions EXP 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of RBMY1A1 gene CTD PMID:23968726 oxaliplatin multiple interactions ISO RGD:1306751 6480464 [Oxaliplatin co-treated with Topotecan] results in decreased expression of RBMXL1 mRNA CTD PMID:25729387 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of RBMXL1 mRNA CTD PMID:17562736 pentachlorophenol increases expression EXP 6480464 Pentachlorophenol results in increased expression of RBMXL1 mRNA CTD PMID:23892564 piperonyl butoxide multiple interactions EXP 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of RBMY1A1 gene CTD PMID:23968726 sunitinib increases expression ISO RGD:1603234 6480464 Sunitinib results in increased expression of RBMXL1 mRNA CTD PMID:31533062 testosterone multiple interactions ISO RGD:1603234 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of RBMXL1 mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:1603234 6480464 Testosterone results in decreased expression of RBMXL1 mRNA CTD PMID:21592394 topotecan multiple interactions ISO RGD:1306751 6480464 [Oxaliplatin co-treated with Topotecan] results in decreased expression of RBMXL1 mRNA CTD PMID:25729387 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of RBMXL1 mRNA CTD PMID:19042947 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of RBMXL1 mRNA CTD PMID:21427059 valproic acid affects expression ISO RGD:1603234 6480464 Valproic Acid affects the expression of RBMXL1 mRNA CTD PMID:25979313
Biological Process
mRNA processing IEA UniProtKB-KW:KW-0507 2290270 UniProt GO_REF:0000004, MGI:1354194 mRNA splice site selection ISO RGD:1306751 2290270 MGI GO_REF:0000096, MGI:4417868 negative regulation of mRNA splicing, via spliceosome ISO RGD:1306751 2290270 MGI GO_REF:0000096, MGI:4417868 positive regulation of mRNA splicing, via spliceosome ISO RGD:1306751 2290270 MGI GO_REF:0000096, MGI:4417868 positive regulation of mRNA splicing, via spliceosome IBA PANTHER:PTN000391532 2290270 MGI:6201960 , PMID:21873635 GO_Central MGI:6201960 , PMID:21873635 positive regulation of transcription by RNA polymerase II IDA 2290270 MGI:3699031 , PMID:17188681 UniProt MGI:3699031 , PMID:17188681 positive regulation of transcription by RNA polymerase II IMP 2290270 MGI:5284748 , PMID:19403048 UniProt MGI:5284748 , PMID:19403048 protein homooligomerization ISO RGD:1306751 2290270 MGI GO_REF:0000096, MGI:4417868 regulation of alternative mRNA splicing, via spliceosome ISO RGD:1306751 2290270 MGI GO_REF:0000096, MGI:4417868 RNA splicing IEA UniProtKB-KW:KW-0508 2290270 UniProt GO_REF:0000004, MGI:1354194