Rbmxl1 (RNA binding motif protein, X-linked like-1) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rbmxl1 (RNA binding motif protein, X-linked like-1) Mus musculus
Analyze
Symbol: Rbmxl1
Name: RNA binding motif protein, X-linked like-1
RGD ID: 1315547
MGI Page MGI
Description: Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to nucleus. Is expressed in central nervous system and sensory organ. Orthologous to human RBMXL1 (RBMX like 1); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: heterogeneous nuclear ribonucleoprotein G; heterogeneous nuclear ribonucleoprotein G (hnRNP G); heterogeneous nuclear ribonucleoprotein G-like 1; Hn; hnRNP G; Hnrpg; MGC102184; Rbmx; Rbmxrt; RNA binding motif protein, X chromosome retrogene; RNA binding motif protein, X linked-like-1; RNA binding motif protein, X-linked-like-1; RNA-binding motif protein, X chromosome
RGD Orthologs
Human
Rat
Bonobo
Green Monkey
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm7324  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39879,231,898 - 79,235,557 (-)NCBIGRCm39mm39
GRCm38878,505,269 - 78,508,928 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl878,505,269 - 78,508,898 (-)EnsemblGRCm38mm10GRCm38
MGSCv37881,029,168 - 81,032,827 (-)NCBIGRCm37mm9NCBIm37
MGSCv36881,401,341 - 81,405,000 (-)NCBImm8
Celera882,781,894 - 82,785,553 (-)NCBICelera
Cytogenetic Map8C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8617202   PMID:9457683   PMID:10349636   PMID:10391207   PMID:10512203   PMID:10716735   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12904583  
PMID:15782199   PMID:15840001   PMID:16033648   PMID:16141072   PMID:16141073   PMID:16919269   PMID:17188681   PMID:18799693   PMID:19403048   PMID:19723774   PMID:19858291   PMID:21873635  
PMID:23604909   PMID:24457600   PMID:28378742   PMID:30068389   PMID:30595499   PMID:31138677   PMID:32098917   PMID:32325033   PMID:32968282  


Genomics

Comparative Map Data
Rbmxl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39879,231,898 - 79,235,557 (-)NCBIGRCm39mm39
GRCm38878,505,269 - 78,508,928 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl878,505,269 - 78,508,898 (-)EnsemblGRCm38mm10GRCm38
MGSCv37881,029,168 - 81,032,827 (-)NCBIGRCm37mm9NCBIm37
MGSCv36881,401,341 - 81,405,000 (-)NCBImm8
Celera882,781,894 - 82,785,553 (-)NCBICelera
Cytogenetic Map8C1NCBI
RBMXL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl188,979,456 - 88,992,960 (-)EnsemblGRCh38hg38GRCh38
GRCh38188,979,456 - 88,992,629 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37189,445,139 - 89,458,643 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36189,218,710 - 89,231,104 (-)NCBINCBI36hg18NCBI36
Celera187,690,929 - 87,704,434 (-)NCBI
Cytogenetic Map1p22.2NCBI
HuRef187,562,493 - 87,576,019 (-)NCBIHuRef
CHM1_1189,560,200 - 89,573,685 (-)NCBICHM1_1
Rbmxl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01933,081,473 - 33,084,988 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1933,083,412 - 33,084,915 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01943,973,668 - 43,977,183 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41931,310,317 - 31,313,892 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11931,314,771 - 31,318,720 (+)NCBI
Celera1928,906,579 - 28,910,137 (+)NCBICelera
Cytogenetic Map19q11NCBI
RBMXL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v0191,695,452 - 91,708,711 (-)NCBIMhudiblu_PPA_v0panPan3
RBMXL1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12044,416,179 - 44,428,807 (+)NCBI

Position Markers
Rbmxrt  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8C1UniSTS
cM Map8 UniSTS
cM Map837.04UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:46
Interacting mature miRNAs:47
Transcripts:ENSMUST00000049245
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001252089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001358975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC101757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF031568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY262810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF437351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB886963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC944372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000049245   ⟹   ENSMUSP00000048153
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,505,269 - 78,508,898 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211719   ⟹   ENSMUSP00000147384
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,505,277 - 78,508,879 (-)Ensembl
RefSeq Acc Id: NM_001252089   ⟹   NP_001239018
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39879,231,898 - 79,235,557 (-)NCBI
GRCm38878,505,269 - 78,508,928 (-)ENTREZGENE
Celera882,781,894 - 82,785,553 (-)ENTREZGENE
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001358974   ⟹   NP_001345903
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39879,231,898 - 79,235,197 (-)NCBI
GRCm38878,505,269 - 78,508,568 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001358975   ⟹   NP_001345904
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39879,231,898 - 79,235,197 (-)NCBI
GRCm38878,505,269 - 78,508,568 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009033   ⟹   NP_033059
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39879,231,898 - 79,235,557 (-)NCBI
GRCm38878,505,269 - 78,508,928 (-)ENTREZGENE
MGSCv37881,029,168 - 81,032,827 (-)RGD
Celera882,781,894 - 82,785,553 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033059   ⟸   NM_009033
- UniProtKB: Q91VM5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001239018   ⟸   NM_001252089
- UniProtKB: Q91VM5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001345904   ⟸   NM_001358975
RefSeq Acc Id: NP_001345903   ⟸   NM_001358974
RefSeq Acc Id: ENSMUSP00000147384   ⟸   ENSMUST00000211719
RefSeq Acc Id: ENSMUSP00000048153   ⟸   ENSMUST00000049245
Protein Domains
RRM

Promoters
RGD ID:8667533
Promoter ID:EPDNEW_M11798
Type:initiation region
Name:Rbmxl1_1
Description:Mus musculus RNA binding motif protein, X-linked like-1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38878,508,899 - 78,508,959EPDNEW
RGD ID:6843615
Promoter ID:MM_KWN:54933
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000093415,   ENSMUST00000093416,   ENSMUST00000109899,   NM_009033,   NM_029736,   UC009MIA.1,   UC009MIB.1,   UC009MIC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36881,031,961 - 81,033,602 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1343045 AgrOrtholog
Ensembl Genes ENSMUSG00000037070 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000048153 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000147384 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000049245 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000211719 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RBM1CTR UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
  RRM_dom_euk UniProtKB/Swiss-Prot
KEGG Report mmu:19656 UniProtKB/Swiss-Prot
MGD MGI:1343045 ENTREZGENE
NCBI Gene 19656 ENTREZGENE
Pfam RBM1CTR UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
PhenoGen Rbmxl1 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
SMART RRM UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
UniGene Mm.24718 ENTREZGENE
UniProt B0LAC3_MOUSE UniProtKB/TrEMBL
  Q91VM5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary O35479 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-20 Rbmxl1  RNA binding motif protein, X-linked like-1    RNA binding motif protein, X linked-like-1  Symbol and/or name change 5135510 APPROVED
2011-11-22 Rbmxl1  RNA binding motif protein, X linked-like-1  Rbmxl1  RNA binding motif protein, X-linked-like-1  Symbol and/or name change 5135510 APPROVED
2011-11-08 Rbmxl1  RNA binding motif protein, X-linked-like-1  Rbmxrt  RNA binding motif protein, X chromosome retrogene  Symbol and/or name change 5135510 APPROVED