MCMBP (minichromosome maintenance complex binding protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: MCMBP (minichromosome maintenance complex binding protein) Homo sapiens
Analyze
Symbol: MCMBP
Name: minichromosome maintenance complex binding protein
RGD ID: 1315515
HGNC Page HGNC:25782
Description: Enables chromatin binding activity. Involved in DNA-templated DNA replication and sister chromatid cohesion. Located in several cellular components, including MCM complex; cytosol; and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C10orf119; chromosome 10 open reading frame 119; FLJ13081; FLJ36756; MCM-binding protein; MCM-BP; mini-chromosome maintenance complex-binding protein; minichromosome maintenance complex-binding protein
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810119,829,440 - 119,873,581 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10119,829,404 - 119,892,556 (-)EnsemblGRCh38hg38GRCh38
GRCh3710121,588,952 - 121,633,093 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610121,578,962 - 121,622,384 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410121,578,961 - 121,622,256NCBI
Celera10115,320,043 - 115,363,436 (-)NCBICelera
Cytogenetic Map10q26.11NCBI
HuRef10115,217,843 - 115,262,560 (-)NCBIHuRef
CHM1_110121,873,835 - 121,918,009 (-)NCBICHM1_1
T2T-CHM13v2.010120,727,023 - 120,771,125 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell junction  (IDA)
cytosol  (IDA)
MCM complex  (IDA)
nucleoplasm  (IDA)
nucleus  (IDA,IEA)

Molecular Function
chromatin binding  (IBA,IDA,IEA)
protein binding  (IPI)

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14702039   PMID:15146197   PMID:15489334   PMID:16189514   PMID:16344560   PMID:16385451   PMID:16964243   PMID:17296731   PMID:18029348   PMID:19615732   PMID:20090939   PMID:20562859  
PMID:20679368   PMID:21145461   PMID:21196493   PMID:21873635   PMID:22250201   PMID:22540012   PMID:22658674   PMID:22863883   PMID:24190967   PMID:24299456   PMID:24366813   PMID:25036637  
PMID:25246271   PMID:25416956   PMID:25737280   PMID:25921289   PMID:25963833   PMID:26186194   PMID:26344197   PMID:26496610   PMID:26871637   PMID:26972000   PMID:27107014   PMID:27462463  
PMID:27621311   PMID:27684187   PMID:27880917   PMID:28514442   PMID:28515276   PMID:28675297   PMID:28846114   PMID:29229926   PMID:29676528   PMID:29845934   PMID:30108253   PMID:30224337  
PMID:30277474   PMID:30455355   PMID:30948266   PMID:31046837   PMID:31091453   PMID:31871319   PMID:32296183   PMID:32416067   PMID:32466590   PMID:32687490   PMID:33106477   PMID:33462405  
PMID:33742100   PMID:33853758   PMID:33957083   PMID:33961781   PMID:34159380   PMID:34373451   PMID:34901782   PMID:35007762   PMID:35256949   PMID:35271311   PMID:35438632   PMID:35439318  
PMID:35509820   PMID:35563538   PMID:35831314   PMID:35944360   PMID:36114006   PMID:36215168   PMID:36300783   PMID:36424410   PMID:36538041   PMID:36931259   PMID:37827155   PMID:38113892  


Genomics

Comparative Map Data
MCMBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810119,829,440 - 119,873,581 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10119,829,404 - 119,892,556 (-)EnsemblGRCh38hg38GRCh38
GRCh3710121,588,952 - 121,633,093 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610121,578,962 - 121,622,384 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410121,578,961 - 121,622,256NCBI
Celera10115,320,043 - 115,363,436 (-)NCBICelera
Cytogenetic Map10q26.11NCBI
HuRef10115,217,843 - 115,262,560 (-)NCBIHuRef
CHM1_110121,873,835 - 121,918,009 (-)NCBICHM1_1
T2T-CHM13v2.010120,727,023 - 120,771,125 (-)NCBIT2T-CHM13v2.0
Mcmbp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397128,298,165 - 128,342,153 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7128,298,165 - 128,342,219 (-)EnsemblGRCm39 Ensembl
GRCm387128,696,441 - 128,740,429 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7128,696,441 - 128,740,495 (-)EnsemblGRCm38mm10GRCm38
MGSCv377135,839,955 - 135,883,943 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367128,487,589 - 128,531,577 (-)NCBIMGSCv36mm8
Celera7128,535,185 - 128,579,839 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map770.41NCBI
Mcmbp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,702,383 - 192,747,381 (-)NCBIGRCr8
mRatBN7.21183,270,598 - 183,316,975 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,271,980 - 183,316,975 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,622,444 - 191,667,438 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01198,808,519 - 198,853,519 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01191,478,625 - 191,523,753 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01200,118,226 - 200,163,106 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1200,118,228 - 200,163,106 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01207,165,763 - 207,210,643 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,949,938 - 187,954,825 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11188,100,077 - 188,145,559 (-)NCBI
Celera1180,918,115 - 180,963,104 (-)NCBICelera
Cytogenetic Map1q37NCBI
Mcmbp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955551643,760 - 688,299 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955551643,760 - 688,299 (-)NCBIChiLan1.0ChiLan1.0
MCMBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28131,685,141 - 131,733,203 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110131,690,847 - 131,734,361 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010116,396,968 - 116,441,075 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110119,813,627 - 119,857,295 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10119,813,960 - 119,857,295 (-)Ensemblpanpan1.1panPan2
MCMBP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12829,946,228 - 29,996,711 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2829,947,731 - 29,996,846 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2830,089,600 - 30,137,980 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02830,477,893 - 30,527,904 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2830,478,885 - 30,527,881 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12830,031,915 - 30,080,304 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02830,054,700 - 30,103,101 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02830,247,294 - 30,295,685 (-)NCBIUU_Cfam_GSD_1.0
Mcmbp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721316,348,406 - 16,375,829 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364869,185,469 - 9,212,838 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364869,184,865 - 9,212,883 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCMBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14129,670,516 - 129,742,290 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114129,669,147 - 129,742,285 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214141,196,414 - 141,269,426 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCMBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19112,622,094 - 112,665,573 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9112,621,784 - 112,665,589 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604873,897,718 - 73,941,433 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mcmbp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473726,929,067 - 27,000,296 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MCMBP
24 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 10q26.11-26.13(chr10:119273012-123117390)x3 copy number gain See cases [RCV000050701] Chr10:119273012..123117390 [GRCh38]
Chr10:121032524..124876906 [GRCh37]
Chr10:121022514..124866896 [NCBI36]
Chr10:10q26.11-26.13		 pathogenic
GRCh38/hg38 10q25.2-26.3(chr10:111313099-133620674)x3 copy number gain See cases [RCV000051218] Chr10:111313099..133620674 [GRCh38]
Chr10:113072857..135434178 [GRCh37]
Chr10:113062847..135284168 [NCBI36]
Chr10:10q25.2-26.3		 pathogenic
GRCh38/hg38 10q23.31-26.3(chr10:91048545-133620674)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053560]|See cases [RCV000053560] Chr10:91048545..133620674 [GRCh38]
Chr10:92808302..135434178 [GRCh37]
Chr10:92798282..135284168 [NCBI36]
Chr10:10q23.31-26.3		 pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100194215-132432797)x3 copy number gain See cases [RCV000053564] Chr10:100194215..132432797 [GRCh38]
Chr10:101953972..134246301 [GRCh37]
Chr10:101943962..134096291 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:106925303-133620815)x3 copy number gain See cases [RCV000053588] Chr10:106925303..133620815 [GRCh38]
Chr10:108685061..135434319 [GRCh37]
Chr10:108675051..135284309 [NCBI36]
Chr10:10q25.1-26.3		 pathogenic
GRCh38/hg38 10q26.11-26.3(chr10:117866565-133554210)x3 copy number gain See cases [RCV000053589] Chr10:117866565..133554210 [GRCh38]
Chr10:119626076..135367714 [GRCh37]
Chr10:119616066..135217704 [NCBI36]
Chr10:10q26.11-26.3		 pathogenic
NM_024834.3(MCMBP):c.597G>A (p.Trp199Ter) single nucleotide variant Malignant melanoma [RCV000062004] Chr10:119849554 [GRCh38]
Chr10:121609066 [GRCh37]
Chr10:121599056 [NCBI36]
Chr10:10q26.11		 not provided
NM_024834.3(MCMBP):c.596G>A (p.Trp199Ter) single nucleotide variant Malignant melanoma [RCV000062005] Chr10:119849555 [GRCh38]
Chr10:121609067 [GRCh37]
Chr10:121599057 [NCBI36]
Chr10:10q26.11		 not provided
NM_001243194.1(INPP5F):c.611A>C (p.Asn204Thr) single nucleotide variant Malignant melanoma [RCV000068830] Chr10:119826822 [GRCh38]
Chr10:121586334 [GRCh37]
Chr10:121576324 [NCBI36]
Chr10:10q26.11		 not provided
GRCh37/hg19 10q25.2-26.3(chr10:114544537-135427143)x3 copy number gain not provided [RCV000847820] Chr10:114544537..135427143 [GRCh37]
Chr10:10q25.2-26.3		 pathogenic
GRCh38/hg38 10q25.1-26.3(chr10:108102587-133620674)x3 copy number gain See cases [RCV000133688] Chr10:108102587..133620674 [GRCh38]
Chr10:109862345..135434178 [GRCh37]
Chr10:109852335..135284168 [NCBI36]
Chr10:10q25.1-26.3		 pathogenic
GRCh38/hg38 10q25.2-26.12(chr10:112701186-120970617)x3 copy number gain See cases [RCV000137511] Chr10:112701186..120970617 [GRCh38]
Chr10:114460945..122730130 [GRCh37]
Chr10:114450935..122720120 [NCBI36]
Chr10:10q25.2-26.12		 likely pathogenic
GRCh38/hg38 10q24.31-26.3(chr10:100600492-133622588)x3 copy number gain See cases [RCV000137747] Chr10:100600492..133622588 [GRCh38]
Chr10:102360249..135436092 [GRCh37]
Chr10:102350239..135286082 [NCBI36]
Chr10:10q24.31-26.3		 pathogenic
GRCh38/hg38 10q26.11(chr10:119671382-119835587)x3 copy number gain See cases [RCV000141240] Chr10:119671382..119835587 [GRCh38]
Chr10:121430894..121595099 [GRCh37]
Chr10:121420884..121585089 [NCBI36]
Chr10:10q26.11		 uncertain significance
GRCh38/hg38 10q26.11-26.3(chr10:119707856-133613639)x3 copy number gain See cases [RCV000142005] Chr10:119707856..133613639 [GRCh38]
Chr10:121467368..135427143 [GRCh37]
Chr10:121457358..135277133 [NCBI36]
Chr10:10q26.11-26.3		 pathogenic
GRCh37/hg19 10q24.32-26.3(chr10:103288313-135512075)x3 copy number gain See cases [RCV000240457] Chr10:103288313..135512075 [GRCh37]
Chr10:10q24.32-26.3		 pathogenic
GRCh37/hg19 10p13-q26.3(chr10:12829206-135427143) copy number loss Distal 10q deletion syndrome [RCV003319583] Chr10:12829206..135427143 [GRCh37]
Chr10:10p13-q26.3		 pathogenic
GRCh37/hg19 10q24.32-26.3(chr10:104633712-135427143)x3 copy number gain See cases [RCV000449386] Chr10:104633712..135427143 [GRCh37]
Chr10:10q24.32-26.3		 pathogenic
GRCh37/hg19 10q24.2-26.3(chr10:100780957-135427143)x3 copy number gain See cases [RCV000446733] Chr10:100780957..135427143 [GRCh37]
Chr10:10q24.2-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic|uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:106003533-135427143)x3 copy number gain See cases [RCV000510813] Chr10:106003533..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q23.32-26.3(chr10:93283493-135427143)x3 copy number gain See cases [RCV000510972] Chr10:93283493..135427143 [GRCh37]
Chr10:10q23.32-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
NM_001256378.2(MCMBP):c.1021G>A (p.Glu341Lys) single nucleotide variant Inborn genetic diseases [RCV003275907] Chr10:119842575 [GRCh38]
Chr10:121602087 [GRCh37]
Chr10:10q26.11		 uncertain significance
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3		 drug response
GRCh37/hg19 10q26.11-26.3(chr10:121269222-135427143)x3 copy number gain not provided [RCV000683288] Chr10:121269222..135427143 [GRCh37]
Chr10:10q26.11-26.3		 pathogenic
GRCh37/hg19 10q24.33-26.3(chr10:105613040-135427143)x3 copy number gain not provided [RCV000683290] Chr10:105613040..135427143 [GRCh37]
Chr10:10q24.33-26.3		 pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:94346520-135427143)x3 copy number gain not provided [RCV000683291] Chr10:94346520..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3		 pathogenic
GRCh37/hg19 10q25.3-26.13(chr10:117024753-124942806) copy number loss Distal 10q deletion syndrome [RCV000767564] Chr10:117024753..124942806 [GRCh37]
Chr10:10q25.3-26.13		 pathogenic
GRCh37/hg19 10q25.1-26.3(chr10:110022170-135439095) copy number gain not provided [RCV000767665] Chr10:110022170..135439095 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q26.11-26.3(chr10:119996339-135427143)x3 copy number gain not provided [RCV001006356] Chr10:119996339..135427143 [GRCh37]
Chr10:10q26.11-26.3		 pathogenic
Single allele deletion not provided [RCV001391678] Chr10:119302758..124813305 [GRCh37]
Chr10:10q26.11-26.13		 likely pathogenic
GRCh37/hg19 10q25.3-26.3(chr10:118247181-135435319)x3 copy number gain not provided [RCV001537903] Chr10:118247181..135435319 [GRCh37]
Chr10:10q25.3-26.3		 pathogenic
GRCh37/hg19 10q25.3-26.12(chr10:118891670-122349064)x1 copy number loss Astigmatism [RCV001801230] Chr10:118891670..122349064 [GRCh37]
Chr10:10q25.3-26.12		 uncertain significance
GRCh37/hg19 10q25.3-26.13(chr10:117019650-125217066) copy number loss not specified [RCV002052892] Chr10:117019650..125217066 [GRCh37]
Chr10:10q25.3-26.13		 pathogenic
GRCh37/hg19 10q26.11-26.13(chr10:120782191-123155522) copy number gain not specified [RCV002052893] Chr10:120782191..123155522 [GRCh37]
Chr10:10q26.11-26.13		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:108455687-135427143) copy number gain not specified [RCV002052891] Chr10:108455687..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q26.11-26.12(chr10:121307376-121700959)x3 copy number gain not provided [RCV002473633] Chr10:121307376..121700959 [GRCh37]
Chr10:10q26.11-26.12		 uncertain significance
NM_001256378.2(MCMBP):c.434A>G (p.Tyr145Cys) single nucleotide variant Inborn genetic diseases [RCV002683717] Chr10:119853190 [GRCh38]
Chr10:121612702 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.54C>G (p.Phe18Leu) single nucleotide variant Inborn genetic diseases [RCV002882888] Chr10:119872531 [GRCh38]
Chr10:121632043 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.1249C>T (p.Arg417Cys) single nucleotide variant Inborn genetic diseases [RCV002978870] Chr10:119838694 [GRCh38]
Chr10:121598206 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.1114A>C (p.Ile372Leu) single nucleotide variant Inborn genetic diseases [RCV002888484] Chr10:119842482 [GRCh38]
Chr10:121601994 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.536A>G (p.Asn179Ser) single nucleotide variant Inborn genetic diseases [RCV002955719] Chr10:119853088 [GRCh38]
Chr10:121612600 [GRCh37]
Chr10:10q26.11		 likely benign
NM_001256378.2(MCMBP):c.416C>T (p.Thr139Met) single nucleotide variant Inborn genetic diseases [RCV003004422] Chr10:119857351 [GRCh38]
Chr10:121616863 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.52T>A (p.Phe18Ile) single nucleotide variant Inborn genetic diseases [RCV002931224] Chr10:119872533 [GRCh38]
Chr10:121632045 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.598T>C (p.Cys200Arg) single nucleotide variant Inborn genetic diseases [RCV002853827] Chr10:119849553 [GRCh38]
Chr10:121609065 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.1250G>A (p.Arg417His) single nucleotide variant Inborn genetic diseases [RCV002673416] Chr10:119838693 [GRCh38]
Chr10:121598205 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.1634T>A (p.Val545Glu) single nucleotide variant Inborn genetic diseases [RCV002648583] Chr10:119835613 [GRCh38]
Chr10:121595125 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.655C>G (p.Leu219Val) single nucleotide variant Inborn genetic diseases [RCV002652732] Chr10:119849496 [GRCh38]
Chr10:121609008 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.253T>C (p.Tyr85His) single nucleotide variant Inborn genetic diseases [RCV003195592] Chr10:119859073 [GRCh38]
Chr10:121618585 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.284A>G (p.His95Arg) single nucleotide variant Inborn genetic diseases [RCV003220052] Chr10:119859042 [GRCh38]
Chr10:121618554 [GRCh37]
Chr10:10q26.11		 likely benign
GRCh37/hg19 10p14-q26.3(chr10:11138692-135427143) copy number gain Distal trisomy 10q [RCV003319593] Chr10:11138692..135427143 [GRCh37]
Chr10:10p14-q26.3		 pathogenic
NM_001256378.2(MCMBP):c.1482G>C (p.Gln494His) single nucleotide variant Inborn genetic diseases [RCV003262286] Chr10:119836956 [GRCh38]
Chr10:121596468 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.521T>C (p.Met174Thr) single nucleotide variant Inborn genetic diseases [RCV003342183] Chr10:119853103 [GRCh38]
Chr10:121612615 [GRCh37]
Chr10:10q26.11		 uncertain significance
NM_001256378.2(MCMBP):c.1767T>G (p.Asp589Glu) single nucleotide variant Inborn genetic diseases [RCV003373652] Chr10:119832041 [GRCh38]
Chr10:121591553 [GRCh37]
Chr10:10q26.11		 uncertain significance
GRCh37/hg19 10q25.1-26.3(chr10:111378692-135427143)x3 copy number gain Distal trisomy 10q [RCV003458955] Chr10:111378692..135427143 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
GRCh37/hg19 10q25.1-26.3(chr10:111447991-133435388)x3 copy number gain not provided [RCV003484817] Chr10:111447991..133435388 [GRCh37]
Chr10:10q25.1-26.3		 pathogenic
NM_001256378.2(MCMBP):c.201A>G (p.Lys67=) single nucleotide variant not provided [RCV003394525] Chr10:119859125 [GRCh38]
Chr10:121618637 [GRCh37]
Chr10:10q26.11		 likely benign
GRCh37/hg19 10q25.1-26.13(chr10:107129993-123817654)x3 copy number gain not specified [RCV003986891] Chr10:107129993..123817654 [GRCh37]
Chr10:10q25.1-26.13		 likely pathogenic
GRCh37/hg19 10q23.33-26.3(chr10:95078198-135427143)x3 copy number gain not specified [RCV003986893] Chr10:95078198..135427143 [GRCh37]
Chr10:10q23.33-26.3		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1002
Count of miRNA genes:617
Interacting mature miRNAs:712
Transcripts:ENST00000360003, ENST00000369077, ENST00000466047, ENST00000495407, ENST00000569515
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
A005M41  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710121,589,420 - 121,589,534UniSTSGRCh37
Build 3610121,579,410 - 121,579,524RGDNCBI36
Celera10115,320,491 - 115,320,605RGD
Cytogenetic Map10q26.11UniSTS
HuRef10115,218,347 - 115,218,461UniSTS
GeneMap99-GB4 RH Map10536.65UniSTS
SGC32380  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710121,588,505 - 121,588,613UniSTSGRCh37
Build 3610121,578,495 - 121,578,603RGDNCBI36
Celera10115,319,576 - 115,319,684RGD
Cytogenetic Map10q26.11UniSTS
HuRef10115,217,432 - 115,217,540UniSTS
Whitehead-RH Map10638.0UniSTS
WI-17160  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710121,630,899 - 121,631,002UniSTSGRCh37
Build 3610121,620,889 - 121,620,992RGDNCBI36
Celera10115,361,941 - 115,362,044RGD
Cytogenetic Map10q26.11UniSTS
HuRef10115,260,319 - 115,260,422UniSTS
GeneMap99-GB4 RH Map10536.65UniSTS
Whitehead-RH Map10639.4UniSTS
G32243  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3710121,589,420 - 121,589,534UniSTSGRCh37
Celera10115,320,491 - 115,320,605UniSTS
Cytogenetic Map10q26.11UniSTS
HuRef10115,218,347 - 115,218,461UniSTS
D1S1423  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map10p12.1-p11.2UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map3p24.2UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map7p15.2UniSTS
Cytogenetic Map6p21UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map6p22.3-p21.32UniSTS
Cytogenetic Map6q22.33UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map22q11.22UniSTS
Cytogenetic Map11q13.2-q13.3UniSTS
Cytogenetic Map3q22-q24UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map7q32UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map7q11.2UniSTS
Cytogenetic Map1p22.1UniSTS
Cytogenetic Map2q32UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic Map9q12UniSTS
Cytogenetic Map3q26.2UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map10q23-q24UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map2p12UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map18q22.1UniSTS
Cytogenetic Map13q12UniSTS
Cytogenetic Map10p14-p13UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map11q23-q24UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map16q13UniSTS
Cytogenetic Map11q25UniSTS
Cytogenetic Map22cen-q12.3UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map15q11.2-q21.3UniSTS
Cytogenetic Map1p21.2UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map7q31.1UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map3q25UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map14q31.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map10p15.1UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map12p13.32UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map2q14UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic MapXq26.3UniSTS
Cytogenetic Map8q24.11UniSTS
Cytogenetic Map9q22.31UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map4q28UniSTS
Cytogenetic Map15q24.1UniSTS
Cytogenetic Map1q41-q42UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map12p13.1-p12.3UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map1p13.1UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map7q33UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map4q23UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map10q26.11UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map11q24.1UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map18p11.31UniSTS
Cytogenetic Map2q24.3UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map12q23.2UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map9q22.2UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map18p11.31-p11.21UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map3q13UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map7p21.2UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic Map1q42.1UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map1p34-p33UniSTS
Cytogenetic Map3q22.1UniSTS
Cytogenetic Map7p14UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map12q24.2UniSTS
Cytogenetic Map20q13UniSTS
Cytogenetic Map19q13.3-q13.4UniSTS
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map8p23-p22UniSTS
Cytogenetic Map1p12UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map10p12.33UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map3q26UniSTS
Cytogenetic Map9p21.2UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map5q21.3UniSTS
Cytogenetic Map1p36.22UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map3q26.31UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map9q21.11UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map22q13.31UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map10q22.1UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic MapXp22UniSTS
Cytogenetic Map20p12.3-p11.21UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic MapXq27.2UniSTS
Cytogenetic Map4q31.1UniSTS
Cytogenetic Map4q31UniSTS
Cytogenetic Map22q13.1-q13.2UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map10q24.3UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map2p13UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map11q22.1UniSTS
Cytogenetic Map12q14.2UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map20q11.21-q11.23UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map21p11.1UniSTS
Cytogenetic Map1p35-p34.3UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map12q24.31-q24.32UniSTS
Cytogenetic Map17q21.1UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map14q32.1UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map16q23.2UniSTS
Cytogenetic Map7q32.1UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map4q31.23UniSTS
Cytogenetic Map11p15.3UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map2p22.3UniSTS
Cytogenetic Map22q13UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map16p13.12UniSTS
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map9p12UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map15q15.2UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map13q33.3UniSTS
Cytogenetic Map15q22-q24UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map14q21.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map15q23UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map4p15.31UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map20q13.1UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic Map10q23.33UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map15q22.1-q22.31UniSTS
Cytogenetic Map1q31-q41UniSTS
Cytogenetic Map6q23.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map14q23UniSTS
Cytogenetic Map12q11-q12UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map1p32UniSTS
Cytogenetic Map3p21.1-p14.2UniSTS
Cytogenetic Map12q22-q23.1UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map6q24.2UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map20q11.22-q11.23UniSTS
Cytogenetic Map3p22.3UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic MapXq13-q21UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map16p13.13UniSTS
Cytogenetic Map10pter-q25.3UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map12q24UniSTS
Cytogenetic Map3q28-q29UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map6p22.2UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map12q24.2-q24.31UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map1q32.2-q41UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map22q11UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map16p13.11UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map9p21UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map11q13.1-q13.3UniSTS
Cytogenetic Map16p13UniSTS
Cytogenetic Map15q26UniSTS
Cytogenetic Map18q21UniSTS
Cytogenetic Map4p15.1-p14UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic Map16q22UniSTS
Cytogenetic Map15q11-q13UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic MapXp22.12UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map5q33.2UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map7q32.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map10q26.13UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map15q25.1UniSTS
Cytogenetic Map9p13UniSTS
Cytogenetic Map2p24.2UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map11q12.2UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map6p24-p22.3UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map3q21-q24UniSTS
Cytogenetic Map4q13UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map5q21.2UniSTS
Cytogenetic Map4q34.3UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map13q13.3UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map1q31UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map8q24.12UniSTS
Cytogenetic Map15q22UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map13q11-q12UniSTS
Cytogenetic Map10q24.2UniSTS
Cytogenetic Map15q21.1UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map6q25.2UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map6q14.1UniSTS
Cytogenetic Map3q23-q24UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map20pter-p12UniSTS
Cytogenetic MapXp22.11UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map16q22.3UniSTS
Cytogenetic Map7q31.3UniSTS
Cytogenetic Map21q22.13UniSTS
Cytogenetic Map1p21UniSTS
Cytogenetic Map8p11UniSTS
Cytogenetic Map7p14.2UniSTS
Cytogenetic Map8p11.23UniSTS
Cytogenetic Map18p11.22UniSTS
Cytogenetic Map18q21.33UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map14q22.2UniSTS
Cytogenetic Map20p11.22-p11.1UniSTS
Cytogenetic Map6p21.31UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map2q12.2UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map11q12-q13UniSTS
Cytogenetic Map18q21.1UniSTS
Cytogenetic Map10p11.21UniSTS
Cytogenetic Map6p22-p21UniSTS
Cytogenetic Map17q21.1-q21.3UniSTS
Cytogenetic Map12q24.33UniSTS
Cytogenetic Map4p15.32UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map12p13.2-p12.3UniSTS
Cytogenetic Map9q22.32UniSTS
Cytogenetic Map1p36.3-p36.2UniSTS
Cytogenetic Map5q22.2UniSTS
Cytogenetic Map4p15.2UniSTS
Cytogenetic Map4p15.3UniSTS
Cytogenetic Map4q28.1UniSTS
Cytogenetic Map12q13.1-q13.2UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map1p31UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map9p22.3UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map8q21.11UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map2q33.3UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map6q22.32UniSTS
Cytogenetic Map5q34UniSTS
Cytogenetic Map5p15.2UniSTS
Cytogenetic Map5q11.2UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map18q12.2UniSTS
Cytogenetic Map14q21.3UniSTS
Cytogenetic Map13q33.1UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map12q23.1UniSTS
Cytogenetic Map16p12.1UniSTS
Cytogenetic Map2q33UniSTS
Cytogenetic Map5q12.1UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map10q22.3-q23.2UniSTS
Cytogenetic Map7p15UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map11q21UniSTS
Cytogenetic Map4q21.3UniSTS
Cytogenetic Map7p13-p12UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map4q22UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map3q12.1UniSTS
Cytogenetic Map7q21.1-q22UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map3q13.13-q13.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map3q26.32UniSTS
Cytogenetic Map15qUniSTS
Cytogenetic Map2p13.2UniSTS
Cytogenetic Map3p12.3UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map3q11.2UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map13q14.13UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map3q21.1UniSTS
Cytogenetic Map10q11.21UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map6p24.2UniSTS
Cytogenetic Map20q13.33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2280 2070 1330 365 1669 218 4062 1490 1665 322 1369 1603 160 1204 2497 4
Low 157 917 394 258 282 246 293 706 2046 96 84 8 12 291 1
Below cutoff 1 1 2 1 19 1 6 1 3 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001256378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001256379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_024834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005270157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011540170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017016663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017016664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054366758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054366759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA292620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC027672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ929053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN259319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR457299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA381502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU178788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU178789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000360003   ⟹   ENSP00000353098
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10119,829,404 - 119,872,754 (-)Ensembl
RefSeq Acc Id: ENST00000369077   ⟹   ENSP00000358073
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10119,829,440 - 119,872,843 (-)Ensembl
RefSeq Acc Id: ENST00000466047
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10119,831,201 - 119,873,621 (-)Ensembl
RefSeq Acc Id: ENST00000495407
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10119,842,782 - 119,858,237 (-)Ensembl
RefSeq Acc Id: ENST00000569515
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl10119,859,050 - 119,892,556 (-)Ensembl
RefSeq Acc Id: NM_001256378   ⟹   NP_001243307
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810119,829,440 - 119,872,843 (-)NCBI
GRCh3710121,588,916 - 121,633,140 (-)NCBI
HuRef10115,217,843 - 115,262,560 (-)NCBI
CHM1_110121,873,835 - 121,917,264 (-)NCBI
T2T-CHM13v2.010120,727,023 - 120,770,387 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001256379   ⟹   NP_001243308
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810119,829,440 - 119,873,581 (-)NCBI
GRCh3710121,588,916 - 121,633,140 (-)NCBI
HuRef10115,217,843 - 115,262,560 (-)NCBI
CHM1_110121,873,835 - 121,918,009 (-)NCBI
T2T-CHM13v2.010120,727,023 - 120,771,125 (-)NCBI
Sequence:
RefSeq Acc Id: NM_024834   ⟹   NP_079110
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810119,829,440 - 119,872,843 (-)NCBI
GRCh3710121,588,916 - 121,633,140 (-)NCBI
Build 3610121,578,962 - 121,622,384 (-)NCBI Archive
Celera10115,320,043 - 115,363,436 (-)RGD
HuRef10115,217,843 - 115,262,560 (-)NCBI
CHM1_110121,873,835 - 121,917,264 (-)NCBI
T2T-CHM13v2.010120,727,023 - 120,770,387 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005270157   ⟹   XP_005270214
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810119,829,440 - 119,872,843 (-)NCBI
GRCh3710121,588,916 - 121,633,140 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011540170   ⟹   XP_011538472
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810119,829,440 - 119,873,581 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017016663   ⟹   XP_016872152
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810119,829,440 - 119,872,843 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054366758   ⟹   XP_054222733
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.010120,727,023 - 120,770,387 (-)NCBI
RefSeq Acc Id: XM_054366759   ⟹   XP_054222734
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.010120,727,023 - 120,770,387 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_079110   ⟸   NM_024834
- Peptide Label: isoform 1
- UniProtKB: Q9BVT9 (UniProtKB/Swiss-Prot),   Q6IA56 (UniProtKB/Swiss-Prot),   B3KSP7 (UniProtKB/Swiss-Prot),   Q9H916 (UniProtKB/Swiss-Prot),   Q9BTE3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001243308   ⟸   NM_001256379
- Peptide Label: isoform 3
- UniProtKB: Q9BTE3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001243307   ⟸   NM_001256378
- Peptide Label: isoform 2
- UniProtKB: A0A0S2Z5P5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005270214   ⟸   XM_005270157
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011538472   ⟸   XM_011540170
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_016872152   ⟸   XM_017016663
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000353098   ⟸   ENST00000360003
RefSeq Acc Id: ENSP00000358073   ⟸   ENST00000369077
RefSeq Acc Id: XP_054222734   ⟸   XM_054366759
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054222733   ⟸   XM_054366758
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9BTE3-F1-model_v2 AlphaFold Q9BTE3 1-642 view protein structure

Promoters
RGD ID:7218823
Promoter ID:EPDNEW_H15157
Type:initiation region
Name:MCMBP_1
Description:minichromosome maintenance complex binding protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15158  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3810119,872,843 - 119,872,903EPDNEW
RGD ID:6809799
Promoter ID:HG_ACW:9962
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:C10ORF119.HAPR07
Position:
Human AssemblyChrPosition (strand)Source
Build 3610121,581,266 - 121,581,766 (-)MPROMDB
RGD ID:6787393
Promoter ID:HG_KWN:11401
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:UC001LEQ.1,   UC001LET.1
Position:
Human AssemblyChrPosition (strand)Source
Build 3610121,602,966 - 121,603,466 (-)MPROMDB
RGD ID:6787648
Promoter ID:HG_KWN:11403
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000369077,   NM_024834
Position:
Human AssemblyChrPosition (strand)Source
Build 3610121,622,249 - 121,622,749 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:25782 AgrOrtholog
COSMIC MCMBP COSMIC
Ensembl Genes ENSG00000197771 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000360003 ENTREZGENE
  ENST00000360003.7 UniProtKB/Swiss-Prot
  ENST00000369077 ENTREZGENE
  ENST00000369077.4 UniProtKB/Swiss-Prot
GTEx ENSG00000197771 GTEx
HGNC ID HGNC:25782 ENTREZGENE
Human Proteome Map MCMBP Human Proteome Map
InterPro MCM_complex-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:79892 UniProtKB/Swiss-Prot
NCBI Gene 79892 ENTREZGENE
OMIM 610909 OMIM
PANTHER MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13489 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MCM_bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134862625 PharmGKB
UniProt A0A0S2Z5P5 ENTREZGENE, UniProtKB/TrEMBL
  A0A0S2Z614_HUMAN UniProtKB/TrEMBL
  B3KSP7 ENTREZGENE
  MCMBP_HUMAN UniProtKB/Swiss-Prot
  Q6IA56 ENTREZGENE
  Q9BTE3 ENTREZGENE
  Q9BVT9 ENTREZGENE
  Q9H916 ENTREZGENE
UniProt Secondary B3KSP7 UniProtKB/Swiss-Prot
  Q6IA56 UniProtKB/Swiss-Prot
  Q9BVT9 UniProtKB/Swiss-Prot
  Q9H916 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 MCMBP  minichromosome maintenance complex binding protein  C10orf119  chromosome 10 open reading frame 119  Symbol and/or name change 5135510 APPROVED