1,1-dichloroethene increases expression EXP 6480464 vinylidene chloride results in increased expression of SMC4 mRNA CTD PMID:26682919 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of SMC4 mRNA CTD PMID:22206623 17beta-estradiol increases expression ISO SMC4 (Homo sapiens) 6480464 Estradiol results in increased expression of SMC4 mRNA CTD PMID:16474171 and PMID:19167446 17beta-estradiol decreases expression ISO Smc4 (Rattus norvegicus) 6480464 Estradiol results in decreased expression of SMC4 mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO SMC4 (Homo sapiens) 6480464 Estradiol promotes the reaction [SMC4 protein binds to ESR1 protein] CTD PMID:27156127 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SMC4 mRNA CTD PMID:18691609 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Smc4 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of SMC4 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Smc4 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of SMC4 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SMC4 promoter] CTD PMID:19654925 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO SMC4 (Homo sapiens) 6480464 2 more ... CTD PMID:17547211 and PMID:19031421 2-methylcholine affects expression ISO SMC4 (Homo sapiens) 6480464 beta-methylcholine affects the expression of SMC4 mRNA CTD PMID:21179406 4-hydroxynon-2-enal decreases expression EXP 6480464 4-hydroxy-2-nonenal results in decreased expression of SMC4 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of SMC4 mRNA CTD PMID:28973697 6-propyl-2-thiouracil increases expression ISO Smc4 (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of SMC4 mRNA CTD PMID:30047161 acetamide increases expression ISO Smc4 (Rattus norvegicus) 6480464 acetamide results in increased expression of SMC4 mRNA CTD PMID:31881176 acetylsalicylic acid decreases expression ISO SMC4 (Homo sapiens) 6480464 Aspirin results in decreased expression of SMC4 mRNA CTD PMID:11906190 aflatoxin B1 affects expression ISO SMC4 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of SMC4 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO SMC4 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of SMC4 gene CTD PMID:27153756 aflatoxin B1 increases expression ISO Smc4 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of SMC4 mRNA CTD PMID:23630614 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of SMC4 mRNA CTD PMID:19770486 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of SMC4 mRNA CTD PMID:17178593 all-trans-retinoic acid decreases expression ISO SMC4 (Homo sapiens) 6480464 Tretinoin results in decreased expression of SMC4 mRNA CTD PMID:15498508 and PMID:33167477 amitrole increases expression ISO Smc4 (Rattus norvegicus) 6480464 Amitrole results in increased expression of SMC4 mRNA CTD PMID:30047161 antimycin A increases expression ISO SMC4 (Homo sapiens) 6480464 Antimycin A results in increased expression of SMC4 mRNA CTD PMID:33512557 aristolochic acid A decreases expression ISO SMC4 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of SMC4 mRNA CTD PMID:33212167 arsenous acid increases expression ISO SMC4 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of SMC4 mRNA CTD PMID:17547211 azathioprine decreases expression ISO SMC4 (Homo sapiens) 6480464 Azathioprine results in decreased expression of SMC4 mRNA CTD PMID:22623647 benzene increases expression ISO SMC4 (Homo sapiens) 6480464 Benzene results in increased expression of SMC4 mRNA CTD PMID:19162166 benzo[a]pyrene diol epoxide I decreases expression ISO SMC4 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 more ... benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of SMC4 mRNA CTD PMID:26377693 bis(2-chloroethyl) sulfide decreases expression ISO SMC4 (Homo sapiens) 6480464 Mustard Gas results in decreased expression of SMC4 mRNA CTD PMID:25102026 bisphenol A increases expression ISO SMC4 (Homo sapiens) 6480464 bisphenol A results in increased expression of SMC4 mRNA CTD PMID:16474171 bisphenol A increases expression ISO Smc4 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of SMC4 mRNA CTD PMID:32145629 bisphenol A decreases expression ISO SMC4 (Homo sapiens) 6480464 bisphenol A analog results in decreased expression of SMC4 mRNA more ... CTD PMID:29275510 more ... bisphenol A decreases expression ISO Smc4 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of SMC4 mRNA CTD PMID:25181051 and PMID:26982218 Bisphenol A diglycidyl ether affects splicing EXP 6480464 2 and 2-bis(4-glycidyloxyphenyl)propane affects the splicing of SMC4 mRNA CTD PMID:36464114 Bisphenol B decreases expression ISO SMC4 (Homo sapiens) 6480464 bisphenol B results in decreased expression of SMC4 mRNA CTD PMID:32387340 cadmium atom decreases expression ISO SMC4 (Homo sapiens) 6480464 Cadmium results in decreased expression of SMC4 mRNA CTD PMID:21120746 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SMC4 mRNA CTD PMID:37325564 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SMC4 mRNA CTD PMID:24982889 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SMC4 mRNA CTD PMID:37325564 cadmium dichloride increases expression ISO SMC4 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of SMC4 mRNA CTD PMID:26472689 caffeine decreases phosphorylation ISO SMC4 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of SMC4 protein CTD PMID:35688186 calcitriol multiple interactions ISO SMC4 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of SMC4 mRNA CTD PMID:21592394 calcitriol decreases expression ISO SMC4 (Homo sapiens) 6480464 Calcitriol results in decreased expression of SMC4 mRNA CTD PMID:21592394 carbamazepine affects expression ISO SMC4 (Homo sapiens) 6480464 Carbamazepine affects the expression of SMC4 mRNA CTD PMID:25979313 CGP 52608 multiple interactions ISO SMC4 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to SMC4 gene] CTD PMID:28238834 chloroprene increases expression ISO Smc4 (Rattus norvegicus) 6480464 Chloroprene results in increased expression of SMC4 mRNA CTD PMID:23125180 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of SMC4 mRNA CTD PMID:37019170 cisplatin decreases expression ISO SMC4 (Homo sapiens) 6480464 Cisplatin results in decreased expression of SMC4 mRNA CTD PMID:27392435 cisplatin multiple interactions ISO SMC4 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of SMC4 mRNA CTD PMID:27392435 copper atom increases expression EXP 6480464 Copper results in increased expression of SMC4 mRNA CTD PMID:17205981 copper(0) increases expression EXP 6480464 Copper results in increased expression of SMC4 mRNA CTD PMID:17205981 cordycepin increases expression EXP 6480464 cordycepin results in increased expression of SMC4 mRNA CTD PMID:32042022 coumestrol increases expression ISO SMC4 (Homo sapiens) 6480464 Coumestrol results in increased expression of SMC4 mRNA CTD PMID:19167446 coumestrol multiple interactions ISO SMC4 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of SMC4 mRNA CTD PMID:19770486 cyclosporin A decreases expression ISO SMC4 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of SMC4 mRNA CTD PMID:19159671 more ... D-glucose increases expression EXP 6480464 Glucose results in increased expression of SMC4 mRNA CTD PMID:17178593 deguelin increases expression ISO SMC4 (Homo sapiens) 6480464 deguelin results in increased expression of SMC4 mRNA CTD PMID:33512557 diarsenic trioxide increases expression ISO SMC4 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of SMC4 mRNA CTD PMID:17547211 diethyl maleate increases expression ISO Smc4 (Rattus norvegicus) 6480464 diethyl maleate results in increased expression of SMC4 mRNA CTD PMID:21161181 dioxygen multiple interactions ISO Smc4 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Oxygen deficiency results in increased expression of SMC4 mRNA] CTD PMID:26476374 dioxygen increases expression ISO Smc4 (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of SMC4 mRNA CTD PMID:26476374 doxorubicin decreases expression ISO SMC4 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of SMC4 mRNA CTD PMID:29803840 Enterolactone multiple interactions ISO SMC4 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SMC4 mRNA CTD PMID:19167446 ferroheme b decreases expression EXP 6480464 Heme metabolite results in decreased expression of SMC4 mRNA CTD PMID:19191707 FR900359 increases phosphorylation ISO SMC4 (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of SMC4 protein CTD PMID:37730182 genistein increases expression ISO SMC4 (Homo sapiens) 6480464 Genistein results in increased expression of SMC4 mRNA CTD PMID:16474171 geraniol decreases expression ISO SMC4 (Homo sapiens) 6480464 geraniol results in decreased expression of SMC4 mRNA CTD PMID:27683099 glucose increases expression EXP 6480464 Glucose results in increased expression of SMC4 mRNA CTD PMID:17178593 gold atom multiple interactions EXP 6480464 [Gold co-treated with Polyethylene Glycols] results in decreased expression of SMC4 mRNA CTD PMID:19695318 gold(0) multiple interactions EXP 6480464 [Gold co-treated with Polyethylene Glycols] results in decreased expression of SMC4 mRNA CTD PMID:19695318 heme b decreases expression EXP 6480464 Heme metabolite results in decreased expression of SMC4 mRNA CTD PMID:19191707 hydrogen peroxide affects expression ISO SMC4 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of SMC4 mRNA CTD PMID:23410634 ivermectin decreases expression ISO SMC4 (Homo sapiens) 6480464 Ivermectin results in decreased expression of SMC4 protein CTD PMID:32959892 lead(0) affects expression ISO SMC4 (Homo sapiens) 6480464 Lead affects the expression of SMC4 mRNA CTD PMID:28903495 leflunomide decreases expression ISO SMC4 (Homo sapiens) 6480464 leflunomide results in decreased expression of SMC4 mRNA CTD PMID:28988120 lucanthone decreases expression ISO SMC4 (Homo sapiens) 6480464 Lucanthone results in decreased expression of SMC4 mRNA CTD PMID:21148553 menadione affects expression ISO SMC4 (Homo sapiens) 6480464 Vitamin K 3 affects the expression of SMC4 mRNA CTD PMID:23410634 mercury atom increases expression ISO SMC4 (Homo sapiens) 6480464 Mercury results in increased expression of SMC4 mRNA CTD PMID:17547211 mercury(0) increases expression ISO SMC4 (Homo sapiens) 6480464 Mercury results in increased expression of SMC4 mRNA CTD PMID:17547211 methimazole increases expression ISO Smc4 (Rattus norvegicus) 6480464 Methimazole results in increased expression of SMC4 mRNA CTD PMID:30047161 methotrexate affects expression EXP 6480464 Methotrexate affects the expression of SMC4 mRNA CTD PMID:18502557 methyl methanesulfonate increases expression ISO SMC4 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of SMC4 mRNA CTD PMID:23649840 N-methyl-4-phenylpyridinium decreases expression ISO SMC4 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of SMC4 mRNA CTD PMID:24810058 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SMC4 protein CTD PMID:26558463 N-nitrosodiethylamine multiple interactions EXP 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of SMC4 mRNA] CTD PMID:17854601 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of SMC4 mRNA CTD PMID:17854601 N-Nitrosopyrrolidine decreases expression ISO SMC4 (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in decreased expression of SMC4 mRNA CTD PMID:32234424 nickel atom increases expression ISO SMC4 (Homo sapiens) 6480464 Nickel results in increased expression of SMC4 mRNA CTD PMID:19031421 oxaliplatin multiple interactions ISO Smc4 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of SMC4 mRNA CTD PMID:25729387 oxaliplatin decreases expression ISO Smc4 (Rattus norvegicus) 6480464 oxaliplatin results in decreased expression of SMC4 mRNA CTD PMID:25729387 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SMC4 mRNA CTD PMID:34911549 palbociclib decreases expression ISO SMC4 (Homo sapiens) 6480464 palbociclib results in decreased expression of SMC4 mRNA CTD PMID:22869556 paracetamol increases expression ISO SMC4 (Homo sapiens) 6480464 Acetaminophen results in increased expression of SMC4 mRNA CTD PMID:22230336 PCB138 multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of SMC4 mRNA CTD PMID:37995155 perfluorononanoic acid decreases expression ISO SMC4 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of SMC4 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid decreases expression ISO Smc4 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in decreased expression of SMC4 mRNA CTD PMID:19162173 phenobarbital multiple interactions EXP 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of SMC4 mRNA] CTD PMID:19482888 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of SMC4 mRNA CTD PMID:23091169 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of SMC4 mRNA CTD PMID:19482888 phorbol 13-acetate 12-myristate increases expression ISO SMC4 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased expression of SMC4 mRNA CTD PMID:19031421 pirinixic acid increases expression ISO Smc4 (Rattus norvegicus) 6480464 pirinixic acid results in increased expression of SMC4 mRNA CTD PMID:19162173 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of SMC4 mRNA CTD PMID:17950772 more ... pirinixic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of SMC4 mRNA] CTD PMID:17950772 pregnenolone 16alpha-carbonitrile increases expression ISO Smc4 (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in increased expression of SMC4 mRNA CTD PMID:30047161 progesterone decreases expression ISO SMC4 (Homo sapiens) 6480464 Progesterone results in decreased expression of SMC4 mRNA CTD PMID:21795739 propanal decreases expression ISO SMC4 (Homo sapiens) 6480464 propionaldehyde results in decreased expression of SMC4 mRNA CTD PMID:26079696 quercetin multiple interactions ISO Smc4 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Oxygen deficiency results in increased expression of SMC4 mRNA] CTD PMID:26476374 resveratrol decreases expression ISO SMC4 (Homo sapiens) 6480464 resveratrol results in decreased expression of SMC4 mRNA CTD PMID:15767336 resveratrol multiple interactions ISO SMC4 (Homo sapiens) 6480464 [Coumestrol co-treated with Resveratrol] results in increased expression of SMC4 mRNA and [Plant Extracts co-treated with Resveratrol] results in increased expression of SMC4 mRNA CTD PMID:19167446 and PMID:23557933 resveratrol increases expression ISO SMC4 (Homo sapiens) 6480464 resveratrol results in increased expression of SMC4 mRNA CTD PMID:19167446 rotenone decreases expression ISO Smc4 (Rattus norvegicus) 6480464 Rotenone results in decreased expression of SMC4 mRNA CTD PMID:28374803 rotenone increases expression ISO SMC4 (Homo sapiens) 6480464 Rotenone results in increased expression of SMC4 mRNA CTD PMID:33512557 senecionine increases expression ISO Smc4 (Rattus norvegicus) 6480464 senecionine results in increased expression of SMC4 mRNA CTD PMID:32419051 sodium arsenite increases expression ISO SMC4 (Homo sapiens) 6480464 sodium arsenite results in increased expression of SMC4 mRNA CTD PMID:29301061 sulfadimethoxine increases expression ISO Smc4 (Rattus norvegicus) 6480464 Sulfadimethoxine results in increased expression of SMC4 mRNA CTD PMID:30047161 sunitinib decreases expression ISO SMC4 (Homo sapiens) 6480464 Sunitinib results in decreased expression of SMC4 mRNA CTD PMID:31533062 tamibarotene decreases expression ISO SMC4 (Homo sapiens) 6480464 tamibarotene results in decreased expression of SMC4 mRNA CTD PMID:15498508 tebufenpyrad increases expression ISO SMC4 (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of SMC4 mRNA CTD PMID:33512557 tert-butyl hydroperoxide decreases expression ISO SMC4 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in decreased expression of SMC4 mRNA CTD PMID:15336504 tert-butyl hydroperoxide affects expression ISO SMC4 (Homo sapiens) 6480464 tert-Butylhydroperoxide affects the expression of SMC4 mRNA CTD PMID:23410634 testosterone multiple interactions ISO SMC4 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of SMC4 mRNA CTD PMID:21592394 testosterone decreases expression ISO SMC4 (Homo sapiens) 6480464 Testosterone results in decreased expression of SMC4 mRNA CTD PMID:21592394 and PMID:33359661 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of SMC4 mRNA CTD PMID:27339419 more ... thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of SMC4 protein CTD PMID:24648495 thioacetamide increases expression ISO Smc4 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of SMC4 mRNA CTD PMID:34492290 topotecan multiple interactions ISO Smc4 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of SMC4 mRNA CTD PMID:25729387 trichloroethene decreases expression ISO Smc4 (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of SMC4 mRNA CTD PMID:33387578 triphenyl phosphate increases expression ISO Smc4 (Rattus norvegicus) 6480464 triphenyl phosphate results in increased expression of SMC4 mRNA CTD PMID:30589522 triptonide decreases expression EXP 6480464 triptonide results in decreased expression of SMC4 mRNA CTD PMID:33045310 troglitazone decreases expression ISO SMC4 (Homo sapiens) 6480464 troglitazone results in decreased expression of SMC4 mRNA CTD PMID:19140230 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of SMC4 mRNA CTD PMID:35537566 tungsten decreases expression EXP 6480464 Tungsten results in decreased expression of SMC4 mRNA CTD PMID:30912803 valproic acid decreases expression ISO SMC4 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of SMC4 mRNA CTD PMID:29154799 valproic acid decreases methylation ISO SMC4 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of SMC4 gene CTD PMID:29154799 vancomycin decreases expression EXP 6480464 Vancomycin results in decreased expression of SMC4 mRNA CTD PMID:18930951 vinclozolin increases expression ISO Smc4 (Rattus norvegicus) 6480464 vinclozolin results in increased expression of SMC4 mRNA CTD PMID:20566332