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Gene: Dock3 (dedicator of cyto-kinesis 3) Mus musculus
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Symbol: Dock3
Name: dedicator of cyto-kinesis 3
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); SH3 domain binding (inferred); INVOLVED IN small GTPase mediated signal transduction (inferred); ASSOCIATED WITH abnormal axonal transport; abnormal cerebral cortex morphology; abnormal gait; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cytoplasm; cytosol (ortholog); INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 4,4'-diaminodiphenylmethane; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dedicator of cytokinesis protein 3; mKIAA0299; MOCA; modifier of cell adhesion; PBP; presenilin-binding protein
Orthologs:
Homo sapiens (human) : DOCK3 (dedicator of cytokinesis 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dock3 (dedicator of cyto-kinesis 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dock3 (dedicator of cytokinesis 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DOCK3 (dedicator of cytokinesis 3)
Canis lupus familiaris (dog) : DOCK3 (dedicator of cytokinesis 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dock3 (dedicator of cytokinesis 3)
Sus scrofa (pig) : DOCK3 (dedicator of cytokinesis 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389106,892,825 - 107,232,330 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379106,795,156 - 107,134,240 (-)NCBIGRCm37mm9NCBIm37
MGSCv369106,753,481 - 107,089,960 (-)NCBImm8
Celera9106,516,972 - 106,837,868 (-)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dock3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315430
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.