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Gene: Dock3 (dedicator of cyto-kinesis 3) Mus musculus
Symbol: Dock3
Name: dedicator of cyto-kinesis 3
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); SH3 domain binding (inferred); INVOLVED IN small GTPase mediated signal transduction (inferred); ASSOCIATED WITH abnormal axonal transport; abnormal cerebral cortex morphology; abnormal gait; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cytoplasm; cytosol (ortholog); INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 4,4'-diaminodiphenylmethane; bisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dedicator of cytokinesis protein 3; mKIAA0299; MOCA; modifier of cell adhesion; PBP; presenilin-binding protein
Homo sapiens (human) : DOCK3 (dedicator of cytokinesis 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dock3 (dedicator of cyto-kinesis 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dock3 (dedicator of cytokinesis 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DOCK3 (dedicator of cytokinesis 3)
Canis lupus familiaris (dog) : DOCK3 (dedicator of cytokinesis 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dock3 (dedicator of cytokinesis 3)
Sus scrofa (pig) : DOCK3 (dedicator of cytokinesis 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389106,892,825 - 107,232,330 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379106,795,156 - 107,134,240 (-)NCBIGRCm37mm9NCBIm37
MGSCv369106,753,481 - 107,089,960 (-)NCBImm8
Celera9106,516,972 - 106,837,868 (-)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dock3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315430
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.