Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Atxn2 (ataxin 2) Mus musculus
Analyze
Symbol: Atxn2
Name: ataxin 2
Description: Predicted to have epidermal growth factor receptor binding activity and protein C-terminus binding activity. Involved in several processes, including negative regulation of growth; neuromuscular process; and neuron differentiation. Localizes to the perinuclear region of cytoplasm. Used to study spinocerebellar ataxia type 2. Human ortholog(s) of this gene implicated in late onset Parkinson's disease and spinocerebellar ataxia type 2. Is expressed in several structures, including alimentary system; central nervous system; liver; sensory organ; and spleen. Orthologous to human ATXN2 (ataxin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9630045M23Rik; ataxin-2; ATX2; AW544490; Sca2; spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2, autosomal dominant, ataxin 2); spinocerebellar ataxia 2 homolog; spinocerebellar ataxia type 2 protein homolog
Orthologs:
Homo sapiens (human) : ATXN2 (ataxin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atxn2 (ataxin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atxn2 (ataxin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATXN2 (ataxin 2)
Canis lupus familiaris (dog) : ATXN2 (ataxin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atxn2 (ataxin 2)
Sus scrofa (pig) : ATXN2 (ataxin 2)
Chlorocebus sabaeus (green monkey) : ATXN2 (ataxin 2)
Heterocephalus glaber (naked mole-rat) : Atxn2 (ataxin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl5121,711,337 - 121,816,493 (+)Ensembl
GRCm385121,711,609 - 121,814,950 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375122,161,618 - 122,264,959 (+)NCBIGRCm37mm9NCBIm37
MGSCv365121,972,226 - 122,075,325 (+)NCBImm8
Celera5118,835,912 - 118,905,112 (+)NCBICelera
Cytogenetic Map5 FNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Atxn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315365
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.