Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: LRPPRC (leucine rich pentatricopeptide repeat containing) Homo sapiens
Analyze
Symbol: LRPPRC
Name: leucine rich pentatricopeptide repeat containing
Description: Exhibits beta-tubulin binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in mitochondrion transport along microtubule. Localizes to several cellular components, including condensed nuclear chromosome; mitochondrial nucleoid; and perinuclear region of cytoplasm. Implicated in French Canadian Leigh disease and Leigh disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 130 kDa leucine-rich protein; CLONE-23970; GP130; leucine-rich pentatricopeptide repeat containing; leucine-rich PPR motif-containing protein, mitochondrial; leucine-rich PPR-motif containing; LRP 130; LRP130; LSFC; mitochondrial leucine-rich PPR motif-containing protein
Orthologs:
Mus musculus (house mouse) : Lrpprc (leucine-rich PPR-motif containing)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lrpprc (leucine-rich pentatricopeptide repeat containing)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrpprc (leucine rich pentatricopeptide repeat containing)
Pan paniscus (bonobo/pygmy chimpanzee) : LRPPRC (leucine rich pentatricopeptide repeat containing)
Canis lupus familiaris (dog) : LRPPRC (leucine rich pentatricopeptide repeat containing)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrpprc (leucine rich pentatricopeptide repeat containing)
Sus scrofa (pig) : LRPPRC (leucine rich pentatricopeptide repeat containing)
Chlorocebus sabaeus (African green monkey) : LRPPRC (leucine rich pentatricopeptide repeat containing)
Heterocephalus glaber (naked mole-rat) : Lrpprc (leucine rich pentatricopeptide repeat containing)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl243,886,224 - 43,995,989 (-)EnsemblGRCh38hg38GRCh38
GRCh38243,886,224 - 43,995,989 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37244,113,363 - 44,223,144 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36243,968,391 - 44,076,648 (-)NCBINCBI36hg18NCBI36
Build 34244,026,537 - 44,134,795NCBI
Celera243,952,087 - 44,062,100 (-)NCBI
Cytogenetic Map2p21NCBI
HuRef243,849,689 - 43,959,564 (-)NCBIHuRef
CHM1_1244,042,771 - 44,152,581 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LRPPRC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315270
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.