Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of ARAP2 mRNA | CTD | PMID:23649840 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ARAP2 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of ARAP2 mRNA | CTD | PMID:31614463 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of ARAP2 mRNA | CTD | PMID:29581250 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARAP2 mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARAP2 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARAP2 mRNA | CTD | PMID:32109520 | 2-butoxyethanol | decreases expression | EXP | | 6480464 | n-butoxyethanol results in decreased expression of ARAP2 mRNA | CTD | PMID:19812364 | 2-hydroxypropanoic acid | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ARAP2 mRNA | CTD | PMID:30851411 | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of ARAP2 mRNA | CTD | PMID:25172293 | 3-Nitrobenzanthrone | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | 3-nitrobenzanthrone results in decreased expression of ARAP2 mRNA | CTD | PMID:34036453 | 6-propyl-2-thiouracil | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of ARAP2 mRNA | CTD | PMID:30047161 | aflatoxin B1 | affects expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ARAP2 protein | CTD | PMID:20106945 | aflatoxin B1 | increases methylation | ISO | ARAP2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ARAP2 exon | CTD | PMID:30157460 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of ARAP2 mRNA | CTD | PMID:19770486 | Aflatoxin B2 alpha | increases methylation | ISO | ARAP2 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of ARAP2 exon | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ARAP2 mRNA | CTD | PMID:33167477 | all-trans-retinoic acid | multiple interactions | EXP | | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ARAP2 mRNA | CTD | PMID:36189433 | amitrole | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of ARAP2 mRNA | CTD | PMID:30047161 | antirheumatic drug | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of ARAP2 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ARAP2 mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ARAP2 mRNA] | CTD | PMID:32406909 | azathioprine | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Azathioprine results in increased expression of ARAP2 mRNA | CTD | PMID:22623647 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ARAP2 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ARAP2 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | decreases methylation | ISO | ARAP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of ARAP2 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of ARAP2 intron | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of ARAP2 mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ARAP2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ARAP2 mRNA | CTD | PMID:30816183 and PMID:34947998 | cadmium dichloride | increases methylation | ISO | Arap2 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased methylation of ARAP2 promoter | CTD | PMID:22457795 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of ARAP2 mRNA | CTD | PMID:24982889 | calcitriol | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of ARAP2 mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of ARAP2 mRNA | CTD | PMID:21592394 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ARAP2 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of ARAP2 mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with RELB mutant form] results in increased expression of ARAP2 mRNA | CTD | PMID:23625948 | cisplatin | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ARAP2 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of ARAP2 mRNA | CTD | PMID:27392435 | clorgyline | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Clorgyline results in increased expression of ARAP2 mRNA | CTD | PMID:19691856 | coenzyme Q10 | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | coenzyme Q10 inhibits the reaction [Lipopolysaccharides results in increased expression of ARAP2 mRNA] | CTD | PMID:21370964 | Cuprizon | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Cuprizone results in decreased expression of ARAP2 mRNA | CTD | PMID:27523638 | cyclosporin A | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Cyclosporine results in decreased expression of ARAP2 mRNA | CTD | PMID:21865292 | cyclosporin A | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ARAP2 mRNA | CTD | PMID:20106945 and PMID:25562108 | DDT | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | DDT results in decreased expression of ARAP2 mRNA | CTD | PMID:30207508 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of ARAP2 mRNA | CTD | PMID:17361019 and PMID:21266533 | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ARAP2 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ARAP2 mRNA | CTD | PMID:29803840 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of ARAP2 mRNA | CTD | PMID:29018328 | fluoranthene | multiple interactions | EXP | | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of ARAP2 mRNA | CTD | PMID:28329830 | fonofos | increases methylation | ISO | ARAP2 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of ARAP2 promoter | CTD | PMID:22847954 | formaldehyde | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ARAP2 mRNA | CTD | PMID:23649840 | hydrogen cyanide | increases expression | EXP | | 6480464 | Hydrogen Cyanide results in increased expression of ARAP2 mRNA | CTD | PMID:33914522 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of ARAP2 mRNA | CTD | PMID:19751817 | lipopolysaccharide | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | coenzyme Q10 inhibits the reaction [Lipopolysaccharides results in increased expression of ARAP2 mRNA] more ... | CTD | PMID:21370964 and PMID:35811015 | lipopolysaccharide | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of ARAP2 mRNA | CTD | PMID:21370964 and PMID:35811015 | mercury dibromide | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of ARAP2 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] affects the expression of ARAP2 mRNA | CTD | PMID:27188386 | methimazole | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of ARAP2 mRNA | CTD | PMID:30047161 | mono(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ARAP2 mRNA | CTD | PMID:36189433 | nickel sulfate | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of ARAP2 mRNA | CTD | PMID:22714537 | ochratoxin A | increases methylation | ISO | Arap2 (Rattus norvegicus) | 6480464 | ochratoxin A results in increased methylation of ARAP2 gene | CTD | PMID:26431795 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ARAP2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ARAP2 mRNA | CTD | PMID:34911549 | p-chloromercuribenzoic acid | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of ARAP2 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ARAP2 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | panobinostat results in increased expression of ARAP2 mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ARAP2 mRNA | CTD | PMID:27188386 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ARAP2 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ARAP2 mRNA | CTD | PMID:29067470 | parathion | increases methylation | ISO | ARAP2 (Homo sapiens) | 6480464 | Parathion results in increased methylation of ARAP2 promoter | CTD | PMID:22847954 | parathion | increases expression | EXP | | 6480464 | Parathion results in increased expression of ARAP2 mRNA | CTD | PMID:34813904 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ARAP2 mRNA | CTD | PMID:27153767 | perfluorooctanoic acid | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of ARAP2 mRNA | CTD | PMID:36326898 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of ARAP2 mRNA | CTD | PMID:23091169 | phenylmercury acetate | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of ARAP2 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] affects the expression of ARAP2 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ARAP2 mRNA | CTD | PMID:18301758 and PMID:23811191 | potassium chromate | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of ARAP2 mRNA | CTD | PMID:22714537 | potassium cyanide | increases expression | EXP | | 6480464 | Potassium Cyanide results in increased expression of ARAP2 mRNA | CTD | PMID:33914522 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of ARAP2 mRNA | CTD | PMID:30047161 | quercitrin | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | quercitrin results in increased expression of ARAP2 mRNA | CTD | PMID:25193878 | rac-lactic acid | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ARAP2 mRNA | CTD | PMID:30851411 | rotenone | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of ARAP2 mRNA | CTD | PMID:29955902 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of ARAP2 mRNA] | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased expression of ARAP2 mRNA | CTD | PMID:25351596 | sulfadimethoxine | decreases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of ARAP2 mRNA | CTD | PMID:30047161 | terbufos | increases methylation | ISO | ARAP2 (Homo sapiens) | 6480464 | terbufos results in increased methylation of ARAP2 promoter | CTD | PMID:22847954 | testosterone | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of ARAP2 mRNA | CTD | PMID:21592394 | testosterone | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of ARAP2 mRNA | CTD | PMID:33359661 | testosterone | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Testosterone results in increased expression of ARAP2 mRNA | CTD | PMID:21592394 | tetrachloroethene | increases expression | EXP | | 6480464 | Tetrachloroethylene results in increased expression of ARAP2 mRNA | CTD | PMID:28973375 | tetrachloromethane | increases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of ARAP2 mRNA | CTD | PMID:31150632 | tetraphene | decreases expression | EXP | | 6480464 | benz(a)anthracene results in decreased expression of ARAP2 mRNA | CTD | PMID:26377693 | thioacetamide | increases expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of ARAP2 mRNA | CTD | PMID:23411599 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of ARAP2 mRNA | CTD | PMID:23557971 | trichostatin A | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ARAP2 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ARAP2 mRNA | CTD | PMID:27188386 | triclosan | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Triclosan results in increased expression of ARAP2 mRNA | CTD | PMID:30510588 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of ARAP2 mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of ARAP2 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of ARAP2 mRNA | CTD | PMID:30912803 | urethane | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Urethane results in increased expression of ARAP2 mRNA | CTD | PMID:28818685 | valproic acid | decreases methylation | ISO | ARAP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ARAP2 gene | CTD | PMID:29154799 | valproic acid | affects splicing | ISO | Arap2 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of ARAP2 mRNA | CTD | PMID:29427782 | valproic acid | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] affects the expression of ARAP2 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ARAP2 mRNA | CTD | PMID:26272509 and PMID:29154799 | valproic acid | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ARAP2 mRNA | CTD | PMID:24383497 and PMID:24935251 | valproic acid | affects expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ARAP2 mRNA | CTD | PMID:23179753 | vinclozolin | affects expression | ISO | Arap2 (Rattus norvegicus) | 6480464 | vinclozolin affects the expression of ARAP2 mRNA | CTD | PMID:23034163 | vincristine | decreases expression | ISO | ARAP2 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of ARAP2 mRNA | CTD | PMID:23649840 | zinc atom | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ARAP2 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | ARAP2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ARAP2 mRNA | CTD | PMID:18593933 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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