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Gene: NMB (neuromedin B) Homo sapiens
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Symbol: NMB
Name: neuromedin B
Description: This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC17211; MGC2277; MGC3936; neuromedin-B; Neuromedin-B-32; neuromedin-beta
Orthologs:
Mus musculus (house mouse) : Nmb (neuromedin B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nmb (neuromedin B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nmb (neuromedin B)
Pan paniscus (bonobo/pygmy chimpanzee) : NMB (neuromedin B)
Canis lupus familiaris (dog) : NMB (neuromedin B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nmb (neuromedin B)
Sus scrofa (pig) : NMB (neuromedin B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381584,655,129 - 84,658,611 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371585,198,360 - 85,201,802 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361582,999,364 - 83,002,806 (-)NCBINCBI36hg18NCBI36
Build 341582,999,365 - 83,002,806NCBI
Celera1561,623,887 - 61,627,329 (-)NCBI
Cytogenetic Map15q25.2NCBI
HuRef1561,284,258 - 61,287,701 (-)NCBIHuRef
CHM1_11585,039,491 - 85,042,934 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NMB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315040
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.