Taf1b (TATA-box binding protein associated factor, RNA polymerase I, B) - Rat Genome Database
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Gene: Taf1b (TATA-box binding protein associated factor, RNA polymerase I, B) Mus musculus
Analyze
Symbol: Taf1b
Name: TATA-box binding protein associated factor, RNA polymerase I, B
RGD ID: 1314967
Description: Predicted to have RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly and nucleolar large rRNA transcription by RNA polymerase I. Predicted to localize to RNA polymerase I core factor complex; RNA polymerase transcription factor SL1 complex; and nucleoplasm. Is expressed in heart and limb. Orthologous to human TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B); PARTICIPATES IN RNA polymerase I transcription pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrobenzenesulfonic acid; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930408G01Rik; A230108M10Rik; mTAFI; p6; p63; RNA polymerase I-specific TBP-associated factor 68 kDa; TAFI68; Tafi86; TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B; TATA box-binding protein-associated factor 1B; TATA box-binding protein-associated factor RNA polymerase I subunit B; TBP-associated factor 1B; TBP-associated factor RNA polymerase I 68; transcription factor TAFI68; transcription initiation factor SL1/TIF-IB subunit B
Orthologs:
Related Pseudogenes: Gm19196  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391224,548,580 - 24,608,570 (+)NCBI
GRCm381224,498,581 - 24,558,571 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1224,498,359 - 24,558,539 (+)EnsemblGRCm38mm10GRCm38
MGSCv371225,183,446 - 25,243,436 (+)NCBIGRCm37mm9NCBIm37
MGSCv361225,087,711 - 25,147,443 (+)NCBImm8
Celera1225,959,782 - 26,020,670 (+)NCBICelera
Cytogenetic Map12A1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:2924801   PMID:9050847   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:14691545   PMID:14697507   PMID:15805466  
PMID:16141072   PMID:16141073   PMID:17967808   PMID:20059953   PMID:20211142   PMID:21228480   PMID:21267068   PMID:21873635   PMID:23441852   PMID:24492243   PMID:24928901   PMID:25859222  
PMID:26275350   PMID:32325033  


Genomics

Comparative Map Data
Taf1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391224,548,580 - 24,608,570 (+)NCBI
GRCm381224,498,581 - 24,558,571 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1224,498,359 - 24,558,539 (+)EnsemblGRCm38mm10GRCm38
MGSCv371225,183,446 - 25,243,436 (+)NCBIGRCm37mm9NCBIm37
MGSCv361225,087,711 - 25,147,443 (+)NCBImm8
Celera1225,959,782 - 26,020,670 (+)NCBICelera
Cytogenetic Map12A1.3NCBI
TAF1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl29,843,443 - 9,934,416 (+)EnsemblGRCh38hg38GRCh38
GRCh3829,843,442 - 9,934,416 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3729,983,571 - 10,074,545 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3629,901,024 - 9,991,996 (+)NCBINCBI36hg18NCBI36
Build 3429,934,170 - 10,025,141NCBI
Celera29,899,495 - 9,990,471 (+)NCBI
Cytogenetic Map2p25.1NCBI
HuRef29,834,383 - 9,925,321 (+)NCBIHuRef
CHM1_129,913,254 - 10,004,217 (+)NCBICHM1_1
Taf1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0643,644,931 - 43,722,124 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,644,830 - 43,722,113 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,512,955 - 60,590,183 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4642,127,301 - 42,204,465 (+)NCBIRGSC3.4rn4RGSC3.4
Celera640,405,142 - 40,482,218 (+)NCBICelera
Cytogenetic Map6q16NCBI
Taf1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554875,359,112 - 5,394,707 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554875,359,132 - 5,394,564 (+)NCBIChiLan1.0ChiLan1.0
TAF1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A9,995,957 - 10,088,165 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A9,996,146 - 10,087,740 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A9,834,385 - 9,927,129 (+)NCBIMhudiblu_PPA_v0panPan3
TAF1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl176,873,360 - 6,937,789 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1176,873,275 - 6,940,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Taf1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365326,118,241 - 6,194,506 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAF1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,527,383 - 126,586,274 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,527,381 - 126,586,403 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23134,954,600 - 135,003,444 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAF1B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1497,704,187 - 97,787,639 (-)Ensembl
ChlSab1.11497,704,251 - 97,787,738 (-)NCBI
Taf1b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248655,089,425 - 5,128,228 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301655Bmd12_mbone mineral density 12 (mouse)Not determined12124612697Mouse
1357519Vtbt12_mvertebral trabecular bone trait 12 (mouse)Not determined12124612697Mouse
4141296Femwf9_mfemur work to failure 9 (mouse)Not determined127870733Mouse
4141112Tglq2a_mtriglyceride QTL 2a (mouse)Not determined12127870733Mouse
4141436Chldq7_mcholesterol and HDL QTL 7 (mouse)Not determined12127870733Mouse
9850128Tglq5_mtriglyceride QTL 5 (mouse)Not determined12127870733Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130383077Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132708755Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133380338Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1229013334290301Mouse
26884410Bzwq15_mbi-zygomatic width QTL 15, 16 week (mouse)12360000029700000Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12536844076984429Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12767315941673302Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12800000040000000Mouse
1301037Cd4ts5_mCD4 T cell subset 5 (mouse)Not determined12830244542302582Mouse
1301723Fcsa7_mfemoral cross-sectional area 7 (mouse)Not determined12944100543441113Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12950000084100000Mouse
14746972Manh72_mmandible shape 72 (mouse)121056528244565282Mouse
10401249Bglu15_mblood glucose level 15 (mouse)Not determined121057064344570810Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121161000097210000Mouse
4141516slwr_mslowlearner (mouse)Not determined1234247646342615Mouse
10043977Obq34_mobesity QTL 34 (mouse)Not determined121509733249097332Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121529102578993590Mouse
26884413Bzwq9_mbi-zygomatic width QTL 9, 10 week (mouse)121610000047700000Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121754644680910109Mouse
15039339Nmrs29_mNAFLD-associated magnetic resonance shift 29 (mouse)121777585351775853Mouse
10043848Hdlq90_mHDL QTL 90 (mouse)Not determined121778994051790082Mouse
1300870Ath18_matherosclerosis 18 (mouse)Not determined121820996752210068Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121968983453689834Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122209886756099017Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:70
Count of miRNA genes:64
Interacting mature miRNAs:67
Transcripts:ENSMUST00000075954
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_020614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_028341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC125067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK015111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ068630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK619940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN721617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y09973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000075954   ⟹   ENSMUSP00000075339
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1224,498,359 - 24,558,539 (+)Ensembl
RefSeq Acc Id: ENSMUST00000221372   ⟹   ENSMUSP00000152701
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1224,498,630 - 24,558,539 (+)Ensembl
RefSeq Acc Id: ENSMUST00000222710   ⟹   ENSMUSP00000152862
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1224,498,611 - 24,509,748 (+)Ensembl
RefSeq Acc Id: ENSMUST00000223503
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1224,498,629 - 24,549,725 (+)Ensembl
RefSeq Acc Id: NM_020614   ⟹   NP_065639
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391224,548,580 - 24,608,570 (+)NCBI
GRCm381224,498,581 - 24,558,571 (+)ENTREZGENE
MGSCv371225,183,446 - 25,243,436 (+)RGD
Celera1225,959,782 - 26,020,670 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_028341
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391224,548,580 - 24,608,570 (+)NCBI
GRCm381224,498,581 - 24,558,571 (+)ENTREZGENE
MGSCv371225,183,446 - 25,243,436 (+)RGD
Celera1225,959,782 - 26,020,670 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006515051   ⟹   XP_006515114
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391224,569,654 - 24,608,555 (+)NCBI
GRCm381224,519,655 - 24,558,556 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_065639   ⟸   NM_020614
- UniProtKB: P97358 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006515114   ⟸   XM_006515051
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000152862   ⟸   ENSMUST00000222710
RefSeq Acc Id: ENSMUSP00000075339   ⟸   ENSMUST00000075954
RefSeq Acc Id: ENSMUSP00000152701   ⟸   ENSMUST00000221372
Protein Domains
RRN7-type

Promoters
RGD ID:8678008
Promoter ID:EPDNEW_M17035
Type:initiation region
Name:Taf1b_1
Description:Mus musculus TATA-box binding protein associated factor, RNApolymerase I, B , transcript variant 2, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381224,498,608 - 24,498,668EPDNEW
RGD ID:6823465
Promoter ID:MM_KWN:11348
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Lung,   MEF_B4
Transcripts:NM_020614,   NR_028341,   UC007NEI.1,   UC007NEJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361225,183,329 - 25,183,829 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109577 AgrOrtholog
Ensembl Genes ENSMUSG00000059669 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000075339 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000152701 UniProtKB/TrEMBL
  ENSMUSP00000152862 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000075954 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000221372 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000222710 UniProtKB/TrEMBL
InterPro TAF1B/Rrn7 UniProtKB/Swiss-Prot
  TF_Rrn7_Zf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21340 UniProtKB/Swiss-Prot
MGD MGI:109577 ENTREZGENE
NCBI Gene 21340 ENTREZGENE
PANTHER PTHR31576 UniProtKB/Swiss-Prot
Pfam zf-RRN7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Taf1b PhenoGen
UniGene Mm.39082 ENTREZGENE
  Mm.421402 ENTREZGENE
UniProt A0A1Y7VK37_MOUSE UniProtKB/TrEMBL
  P97358 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary E9QJY7 UniProtKB/Swiss-Prot
  Q08AT7 UniProtKB/Swiss-Prot
  Q3V292 UniProtKB/Swiss-Prot
  Q6NSS9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Taf1b  TATA-box binding protein associated factor, RNA polymerase I, B    TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B  Symbol and/or name change 5135510 APPROVED