Alkbh2 (alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase) - Rat Genome Database

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Gene: Alkbh2 (alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase) Mus musculus
Analyze
Symbol: Alkbh2
Name: alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
RGD ID: 1314959
MGI Page MGI
Description: Enables broad specificity oxidative DNA demethylase activity and cytosine C-5 DNA demethylase activity. Involved in DNA alkylation repair. Predicted to be located in nucleolus and nucleoplasm. Orthologous to human ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9530023G02; Abh; Abh2; alkB, alkylation repair homolog 2; alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; DNA oxidative demethylase ALKBH2; mABH; mABH2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,261,987 - 114,268,782 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,261,987 - 114,266,279 (-)EnsemblGRCm39 Ensembl
GRCm385114,123,926 - 114,131,233 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,123,926 - 114,128,218 (-)EnsemblGRCm38mm10GRCm38
MGSCv375114,573,943 - 114,578,185 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365114,384,933 - 114,389,175 (-)NCBIMGSCv36mm8
Celera5111,225,796 - 111,230,044 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
DNA alkylation repair  (IBA,IMP,ISO,ISS)

Cellular Component
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072  
PMID:16141073   PMID:16174769   PMID:16642038   PMID:17967808   PMID:18519673   PMID:18799693   PMID:21873635   PMID:22429847   PMID:22684101   PMID:26930515   PMID:28726787  


Genomics

Comparative Map Data
Alkbh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,261,987 - 114,268,782 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,261,987 - 114,266,279 (-)EnsemblGRCm39 Ensembl
GRCm385114,123,926 - 114,131,233 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,123,926 - 114,128,218 (-)EnsemblGRCm38mm10GRCm38
MGSCv375114,573,943 - 114,578,185 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365114,384,933 - 114,389,175 (-)NCBIMGSCv36mm8
Celera5111,225,796 - 111,230,044 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.97NCBI
ALKBH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812109,088,189 - 109,093,472 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12109,088,188 - 109,093,631 (-)EnsemblGRCh38hg38GRCh38
GRCh3712109,525,994 - 109,531,277 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,010,379 - 108,015,628 (-)NCBINCBI36Build 36hg18NCBI36
Celera12109,149,917 - 109,155,219 (-)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12106,544,162 - 106,549,711 (-)NCBIHuRef
CHM1_112109,493,646 - 109,498,943 (-)NCBICHM1_1
T2T-CHM13v2.012109,063,001 - 109,068,284 (-)NCBIT2T-CHM13v2.0
Alkbh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,156,825 - 48,161,489 (+)NCBIGRCr8
mRatBN7.21242,494,187 - 42,500,929 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,496,300 - 42,500,914 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1243,663,490 - 43,668,131 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,277,081 - 44,281,722 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,337,598 - 43,342,239 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,257,575 - 48,262,244 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,257,609 - 48,262,243 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,039,893 - 50,044,572 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,531,682 - 43,536,317 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11243,392,394 - 43,399,689 (+)NCBI
Celera1244,100,824 - 44,105,459 (+)NCBICelera
Cytogenetic Map12q16NCBI
Alkbh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,255,292 - 10,265,083 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,258,736 - 10,265,100 (-)NCBIChiLan1.0ChiLan1.0
ALKBH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210117,153,973 - 117,160,045 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112117,150,371 - 117,156,460 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012106,664,678 - 106,670,558 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112110,058,507 - 110,068,225 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,058,507 - 110,063,946 (-)Ensemblpanpan1.1panPan2
ALKBH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,911,892 - 17,918,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,911,763 - 17,917,788 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2617,882,716 - 17,889,612 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02618,256,208 - 18,263,098 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2618,257,880 - 18,264,398 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,092,011 - 18,098,900 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02618,246,822 - 18,253,708 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02618,265,421 - 18,272,096 (+)NCBIUU_Cfam_GSD_1.0
Alkbh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,564,996 - 144,571,765 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936769904,125 - 906,881 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936769904,129 - 908,130 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALKBH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,760,505 - 41,766,090 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,760,427 - 41,766,990 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,326,105 - 44,331,765 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALKBH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111104,292,528 - 104,298,500 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11104,288,454 - 104,298,196 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037140,805,493 - 140,810,976 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alkbh2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,249,352 - 12,258,384 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474712,249,333 - 12,259,248 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Alkbh2
454 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:382
Count of miRNA genes:196
Interacting mature miRNAs:206
Transcripts:ENSMUST00000053657, ENSMUST00000112279, ENSMUST00000149418
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
25314310Syncl4_msynaptonemal complex length 4 (mouse)5103047866115538059Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
25314317Sccor3_msynaptonemal complex length to mean MLH1 count ratio 3 (mouse)5104347866114738061Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined598019649116876624Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
1357886Diht_mdopamine-induced hypothermia (mouse)Not determined5104498738115101540Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5114021753129632606Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4141652Mrdq2_mmodifier of retinal degeneration QTL 2 (mouse)Not determined110253106118093673Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108762509126882944Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse

Markers in Region
AU016977  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385114,124,022 - 114,124,160UniSTSGRCm38
MGSCv375114,574,031 - 114,574,169UniSTSGRCm37
Celera5111,225,884 - 111,226,022UniSTS
Cytogenetic Map5FUniSTS
cM Map561.0UniSTS
Whitehead/MRC_RH51383.51UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001359940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001424653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_188821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_188822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_188823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC129080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG083657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY210211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000053657   ⟹   ENSMUSP00000056043
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,261,987 - 114,266,237 (-)Ensembl
GRCm38.p6 Ensembl5114,123,926 - 114,128,176 (-)Ensembl
Ensembl Acc Id: ENSMUST00000112279   ⟹   ENSMUSP00000107898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,261,996 - 114,266,279 (-)Ensembl
GRCm38.p6 Ensembl5114,123,935 - 114,128,218 (-)Ensembl
Ensembl Acc Id: ENSMUST00000149418   ⟹   ENSMUSP00000142877
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5114,265,667 - 114,266,242 (-)Ensembl
GRCm38.p6 Ensembl5114,127,606 - 114,128,181 (-)Ensembl
RefSeq Acc Id: NM_001359940   ⟹   NP_001346869
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,266,275 (-)NCBI
GRCm385114,123,926 - 114,128,218 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359941   ⟹   NP_001346870
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,266,275 (-)NCBI
GRCm385114,123,926 - 114,128,218 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001424650   ⟹   NP_001411579
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,266,275 (-)NCBI
RefSeq Acc Id: NM_001424651   ⟹   NP_001411580
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,268,782 (-)NCBI
RefSeq Acc Id: NM_001424652   ⟹   NP_001411581
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,268,782 (-)NCBI
RefSeq Acc Id: NM_001424653   ⟹   NP_001411582
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,266,275 (-)NCBI
RefSeq Acc Id: NM_175016   ⟹   NP_778181
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,266,275 (-)NCBI
GRCm385114,123,926 - 114,128,218 (-)NCBI
MGSCv375114,573,943 - 114,578,185 (-)RGD
Celera5111,225,796 - 111,230,044 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_188821
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,266,275 (-)NCBI
RefSeq Acc Id: NR_188822
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,268,782 (-)NCBI
RefSeq Acc Id: NR_188823
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395114,261,987 - 114,266,275 (-)NCBI
RefSeq Acc Id: NP_778181   ⟸   NM_175016
- Peptide Label: isoform 1
- UniProtKB: Q8C591 (UniProtKB/Swiss-Prot),   Q6P6J4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001346870   ⟸   NM_001359941
- Peptide Label: isoform 1
- UniProtKB: Q8C591 (UniProtKB/Swiss-Prot),   Q6P6J4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001346869   ⟸   NM_001359940
- Peptide Label: isoform 1
- UniProtKB: Q8C591 (UniProtKB/Swiss-Prot),   Q6P6J4 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000056043   ⟸   ENSMUST00000053657
Ensembl Acc Id: ENSMUSP00000107898   ⟸   ENSMUST00000112279
Ensembl Acc Id: ENSMUSP00000142877   ⟸   ENSMUST00000149418
RefSeq Acc Id: NP_001411581   ⟸   NM_001424652
- Peptide Label: isoform 1
- UniProtKB: Q8C591 (UniProtKB/Swiss-Prot),   Q6P6J4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001411580   ⟸   NM_001424651
- Peptide Label: isoform 1
- UniProtKB: Q8C591 (UniProtKB/Swiss-Prot),   Q6P6J4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001411582   ⟸   NM_001424653
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001411579   ⟸   NM_001424650
- Peptide Label: isoform 2
Protein Domains
Fe2OG dioxygenase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P6J4-F1-model_v2 AlphaFold Q6P6J4 1-239 view protein structure

Promoters
RGD ID:6887666
Promoter ID:EPDNEW_M7284
Type:multiple initiation site
Name:Alkbh2_1
Description:Mus musculus alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase, transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385114,128,210 - 114,128,270EPDNEW
RGD ID:6837063
Promoter ID:MM_KWN:43536
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000034280,   OTTMUST00000034282,   UC008YZE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365114,577,696 - 114,578,196 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2141032 AgrOrtholog
Ensembl Genes ENSMUSG00000044339 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000053657 ENTREZGENE
  ENSMUST00000053657.13 UniProtKB/Swiss-Prot
  ENSMUST00000112279 ENTREZGENE
  ENSMUST00000112279.2 UniProtKB/Swiss-Prot
  ENSMUST00000149418.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.590 UniProtKB/Swiss-Prot
InterPro AlkB-like UniProtKB/Swiss-Prot
  AlkB-like_sf UniProtKB/Swiss-Prot
  ALKBH2 UniProtKB/Swiss-Prot
  Oxoglu/Fe-dep_dioxygenase UniProtKB/Swiss-Prot
KEGG Report mmu:231642 UniProtKB/Swiss-Prot
MGD MGI:2141032 ENTREZGENE
NCBI Gene Alkbh2 ENTREZGENE
PANTHER DNA OXIDATIVE DEMETHYLASE ALKBH2 UniProtKB/Swiss-Prot
  PTHR31573 UniProtKB/Swiss-Prot
Pfam 2OG-FeII_Oxy_2 UniProtKB/Swiss-Prot
PhenoGen Alkbh2 PhenoGen
PROSITE FE2OG_OXY UniProtKB/Swiss-Prot
Superfamily-SCOP Clavaminate synthase-like UniProtKB/Swiss-Prot
UniProt A0A0G2JER8_MOUSE UniProtKB/TrEMBL
  ALKB2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8C591 ENTREZGENE
UniProt Secondary Q8C591 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Alkbh2  alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase  AU016977  expressed sequence AU016977  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 AU016977  expressed sequence AU016977  Alkbh2  alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase  Symbol and/or name change 5135510 APPROVED
2015-12-22 Alkbh2  alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase    alkB, alkylation repair homolog 2 (E. coli)  Symbol and/or name change 5135510 APPROVED