WDR41 (WD repeat domain 41) - Rat Genome Database

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Gene: WDR41 (WD repeat domain 41) Homo sapiens
Analyze
Symbol: WDR41
Name: WD repeat domain 41
RGD ID: 1314938
HGNC Page HGNC:25601
Description: Contributes to guanyl-nucleotide exchange factor activity. Involved in positive regulation of GTPase activity and regulation of autophagy. Located in cytoplasm. Part of guanyl-nucleotide exchange factor complex. Colocalizes with Atg1/ULK1 kinase complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FLJ10904; MSTP048; WD repeat-containing protein 41
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38577,430,933 - 77,620,577 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl577,425,970 - 77,620,611 (-)EnsemblGRCh38hg38GRCh38
GRCh37576,726,758 - 76,788,141 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36576,763,825 - 76,824,088 (-)NCBINCBI36Build 36hg18NCBI36
Build 34576,763,825 - 76,824,088NCBI
Celera572,622,605 - 72,682,854 (-)NCBICelera
Cytogenetic Map5q13.3-q14.1NCBI
HuRef571,934,855 - 71,995,126 (-)NCBIHuRef
CHM1_1576,161,811 - 76,222,105 (-)NCBICHM1_1
T2T-CHM13v2.0577,913,542 - 77,974,918 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14702039   PMID:15342556   PMID:15489334   PMID:16341674   PMID:17897319   PMID:19913121   PMID:20379614   PMID:20628086   PMID:21502949   PMID:22678362   PMID:26186194   PMID:26638075  
PMID:26871637   PMID:27103069   PMID:27193190   PMID:27617292   PMID:28195531   PMID:28514442   PMID:29395067   PMID:29568061   PMID:29950492   PMID:29995611   PMID:30669939   PMID:31056421  
PMID:31091453   PMID:31871319   PMID:32303654   PMID:32394588   PMID:32848248   PMID:32877691   PMID:33597295   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34226595   PMID:34432599  
PMID:34672954   PMID:34709727   PMID:35241646   PMID:35256949   PMID:35509820   PMID:35844135  


Genomics

Comparative Map Data
WDR41
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38577,430,933 - 77,620,577 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl577,425,970 - 77,620,611 (-)EnsemblGRCh38hg38GRCh38
GRCh37576,726,758 - 76,788,141 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36576,763,825 - 76,824,088 (-)NCBINCBI36Build 36hg18NCBI36
Build 34576,763,825 - 76,824,088NCBI
Celera572,622,605 - 72,682,854 (-)NCBICelera
Cytogenetic Map5q13.3-q14.1NCBI
HuRef571,934,855 - 71,995,126 (-)NCBIHuRef
CHM1_1576,161,811 - 76,222,105 (-)NCBICHM1_1
T2T-CHM13v2.0577,913,542 - 77,974,918 (-)NCBIT2T-CHM13v2.0
Wdr41
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391395,112,226 - 95,161,800 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1395,112,852 - 95,159,822 (+)EnsemblGRCm39 Ensembl
GRCm381394,976,329 - 95,023,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1394,976,344 - 95,023,314 (+)EnsemblGRCm38mm10GRCm38
MGSCv371395,746,303 - 95,793,269 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361396,077,043 - 96,115,230 (+)NCBIMGSCv36mm8
Celera1398,594,444 - 98,641,510 (+)NCBICelera
Cytogenetic Map13C3- D1NCBI
Wdr41
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2226,222,797 - 26,273,840 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl226,224,495 - 26,273,836 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx233,260,068 - 33,309,248 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0231,360,307 - 31,409,491 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0226,178,985 - 26,227,815 (+)NCBIRnor_WKY
Rnor_6.0224,668,108 - 24,717,280 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl224,668,116 - 24,717,267 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0243,827,385 - 43,876,540 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4225,299,797 - 25,349,926 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1225,264,929 - 25,270,296 (+)NCBI
Celera222,294,024 - 22,343,220 (+)NCBICelera
Cytogenetic Map2q12NCBI
Wdr41
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542523,470,278 - 23,514,638 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542523,366,130 - 23,510,897 (+)NCBIChiLan1.0ChiLan1.0
WDR41
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1538,338,267 - 38,398,503 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl538,214,273 - 38,398,503 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0537,809,767 - 37,870,039 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
WDR41
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1329,082,481 - 29,286,632 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl329,073,073 - 29,286,681 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha330,322,335 - 30,526,500 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0329,003,543 - 29,208,015 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl328,994,217 - 29,208,226 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1328,940,203 - 29,142,315 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0328,918,819 - 29,123,031 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0329,249,596 - 29,454,033 (+)NCBIUU_Cfam_GSD_1.0
Wdr41
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213185,240,144 - 185,405,769 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365495,453,913 - 5,494,533 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365495,453,824 - 5,494,809 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR41
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl286,319,014 - 86,380,588 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1286,322,933 - 86,380,619 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2287,933,152 - 88,028,663 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WDR41
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1471,672,474 - 71,719,507 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl471,673,369 - 71,719,491 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604920,510,784 - 20,557,831 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr41
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248691,938,925 - 1,981,045 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248691,936,960 - 1,980,932 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in WDR41
4 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q13.3-22.1(chr5:74163186-110809453)x3 copy number gain See cases [RCV000051839] Chr5:74163186..110809453 [GRCh38]
Chr5:73459011..110145153 [GRCh37]
Chr5:73494767..110173052 [NCBI36]
Chr5:5q13.3-22.1
pathogenic
GRCh38/hg38 5q13.3-14.1(chr5:77018109-78190068)x1 copy number loss See cases [RCV000053473] Chr5:77018109..78190068 [GRCh38]
Chr5:76313934..77485892 [GRCh37]
Chr5:76349690..77521648 [NCBI36]
Chr5:5q13.3-14.1
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32
uncertain significance
GRCh37/hg19 5q13.3(chr5:76683620-76810358)x3 copy number gain not provided [RCV000850000] Chr5:76683620..76810358 [GRCh37]
Chr5:5q13.3
uncertain significance
GRCh37/hg19 5q13.2-15(chr5:72790061-97478870)x3 copy number gain not provided [RCV001005683] Chr5:72790061..97478870 [GRCh37]
Chr5:5q13.2-15
pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4000
Count of miRNA genes:1125
Interacting mature miRNAs:1376
Transcripts:ENST00000296679, ENST00000414719, ENST00000502528, ENST00000503035, ENST00000504895, ENST00000505129, ENST00000506307, ENST00000506474, ENST00000507029, ENST00000507239, ENST00000507452, ENST00000507654, ENST00000508154, ENST00000509701, ENST00000509858, ENST00000509892, ENST00000509971, ENST00000511036, ENST00000511630, ENST00000511791, ENST00000512033, ENST00000512168, ENST00000513417, ENST00000513917, ENST00000514451, ENST00000514559, ENST00000514878, ENST00000515253, ENST00000515321
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-57669  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,747,537 - 76,747,632UniSTSGRCh37
Build 36576,783,293 - 76,783,388RGDNCBI36
Celera572,642,081 - 72,642,176RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,954,327 - 71,954,422UniSTS
TNG Radiation Hybrid Map535854.0UniSTS
SHGC-36700  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,728,888 - 76,728,973UniSTSGRCh37
Build 36576,764,644 - 76,764,729RGDNCBI36
Celera572,623,424 - 72,623,509RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,935,674 - 71,935,759UniSTS
Stanford-G3 RH Map52775.0UniSTS
NCBI RH Map5363.9UniSTS
GeneMap99-G3 RH Map52770.0UniSTS
RH80473  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,728,094 - 76,728,193UniSTSGRCh37
Build 36576,763,850 - 76,763,949RGDNCBI36
Celera572,622,630 - 72,622,729RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,934,880 - 71,934,979UniSTS
GeneMap99-GB4 RH Map5376.16UniSTS
SHGC-133093  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,728,089 - 76,728,367UniSTSGRCh37
Build 36576,763,845 - 76,764,123RGDNCBI36
Celera572,622,625 - 72,622,903RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,934,875 - 71,935,153UniSTS
TNG Radiation Hybrid Map535846.0UniSTS
SHGC-36223  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,762,673 - 76,762,795UniSTSGRCh37
Build 36576,798,429 - 76,798,551RGDNCBI36
Celera572,657,218 - 72,657,340RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,969,470 - 71,969,592UniSTS
Stanford-G3 RH Map52786.0UniSTS
NCBI RH Map5363.9UniSTS
GeneMap99-G3 RH Map52781.0UniSTS
RH44392  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,728,203 - 76,728,338UniSTSGRCh37
Build 36576,763,959 - 76,764,094RGDNCBI36
Celera572,622,739 - 72,622,874RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,934,989 - 71,935,124UniSTS
GeneMap99-GB4 RH Map5368.59UniSTS
NCBI RH Map5363.9UniSTS
RH44320  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,728,161 - 76,728,398UniSTSGRCh37
Build 36576,763,917 - 76,764,154RGDNCBI36
Celera572,622,697 - 72,622,934RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,934,947 - 71,935,184UniSTS
GeneMap99-GB4 RH Map5368.59UniSTS
NCBI RH Map5363.9UniSTS
D5S2319  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,728,924 - 76,729,074UniSTSGRCh37
Build 36576,764,680 - 76,764,830RGDNCBI36
Celera572,623,460 - 72,623,610RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,935,710 - 71,935,860UniSTS
GeneMap99-GB4 RH Map5368.49UniSTS
Whitehead-RH Map5269.9UniSTS
Whitehead-YAC Contig Map5 UniSTS
NCBI RH Map5363.9UniSTS
SHGC-64313  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,728,236 - 76,728,359UniSTSGRCh37
Build 36576,763,992 - 76,764,115RGDNCBI36
Celera572,622,772 - 72,622,895RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,935,022 - 71,935,145UniSTS
WI-20907  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37576,728,196 - 76,728,473UniSTSGRCh37
Build 36576,763,952 - 76,764,229RGDNCBI36
Celera572,622,732 - 72,623,009RGD
Cytogenetic Map5q13.3UniSTS
HuRef571,934,982 - 71,935,259UniSTS
GeneMap99-GB4 RH Map5368.39UniSTS
Whitehead-RH Map5268.9UniSTS
NCBI RH Map5363.9UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 801 1354 872 125 895 65 3090 333 1927 237 1194 1463 73 1 910 1782 3 1
Low 1638 1628 854 499 1050 400 1266 1861 1807 182 266 150 102 294 1006 3 1
Below cutoff 9 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_018268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005248551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005248552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011543505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011543507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047417349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047417350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047417351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001742140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001742141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC010234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC108173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF115511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK295249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL834138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG113002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM818066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP276774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ000743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD656920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC403958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU178690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU178691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000296679   ⟹   ENSP00000296679
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,430,933 - 77,492,316 (-)Ensembl
RefSeq Acc Id: ENST00000502528
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,432,244 - 77,452,873 (-)Ensembl
RefSeq Acc Id: ENST00000503035   ⟹   ENSP00000421166
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,451,291 - 77,492,477 (-)Ensembl
RefSeq Acc Id: ENST00000504895   ⟹   ENSP00000426141
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,453,866 - 77,491,285 (-)Ensembl
RefSeq Acc Id: ENST00000505129   ⟹   ENSP00000425249
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,440,817 - 77,492,496 (-)Ensembl
RefSeq Acc Id: ENST00000506307   ⟹   ENSP00000424327
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,440,931 - 77,492,223 (-)Ensembl
RefSeq Acc Id: ENST00000506474   ⟹   ENSP00000425813
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,453,889 - 77,492,220 (-)Ensembl
RefSeq Acc Id: ENST00000507029   ⟹   ENSP00000424287
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,432,893 - 77,492,316 (-)Ensembl
RefSeq Acc Id: ENST00000507239
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,458,859 - 77,492,222 (-)Ensembl
RefSeq Acc Id: ENST00000507452
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,449,765 - 77,492,215 (-)Ensembl
RefSeq Acc Id: ENST00000507654   ⟹   ENSP00000427291
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,436,379 - 77,492,203 (-)Ensembl
RefSeq Acc Id: ENST00000508154
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,426,654 - 77,433,159 (-)Ensembl
RefSeq Acc Id: ENST00000509701   ⟹   ENSP00000427652
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,437,407 - 77,492,220 (-)Ensembl
RefSeq Acc Id: ENST00000509858
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,463,093 - 77,620,576 (-)Ensembl
RefSeq Acc Id: ENST00000509892   ⟹   ENSP00000427219
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,449,804 - 77,492,215 (-)Ensembl
RefSeq Acc Id: ENST00000509971   ⟹   ENSP00000422922
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,453,879 - 77,620,611 (-)Ensembl
RefSeq Acc Id: ENST00000511036   ⟹   ENSP00000422510
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,451,324 - 77,492,487 (-)Ensembl
RefSeq Acc Id: ENST00000511630   ⟹   ENSP00000425563
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,436,360 - 77,451,353 (-)Ensembl
RefSeq Acc Id: ENST00000511791   ⟹   ENSP00000423540
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,438,258 - 77,492,287 (-)Ensembl
RefSeq Acc Id: ENST00000512033
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,426,652 - 77,436,279 (-)Ensembl
RefSeq Acc Id: ENST00000512168
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,463,124 - 77,492,507 (-)Ensembl
RefSeq Acc Id: ENST00000513417   ⟹   ENSP00000423462
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,449,831 - 77,492,220 (-)Ensembl
RefSeq Acc Id: ENST00000513917
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,463,106 - 77,499,636 (-)Ensembl
RefSeq Acc Id: ENST00000514451
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,463,106 - 77,492,003 (-)Ensembl
RefSeq Acc Id: ENST00000514559   ⟹   ENSP00000426937
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,451,291 - 77,492,222 (-)Ensembl
RefSeq Acc Id: ENST00000514878
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,425,970 - 77,432,955 (-)Ensembl
RefSeq Acc Id: ENST00000515253   ⟹   ENSP00000426499
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,432,813 - 77,492,199 (-)Ensembl
RefSeq Acc Id: ENST00000515321
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl577,449,815 - 77,492,221 (-)Ensembl
RefSeq Acc Id: NM_018268   ⟹   NP_060738
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,430,933 - 77,492,316 (-)NCBI
GRCh37576,727,622 - 76,788,332 (-)NCBI
Build 36576,763,825 - 76,824,088 (-)NCBI Archive
Celera572,622,605 - 72,682,854 (-)RGD
HuRef571,934,855 - 71,995,126 (-)RGD
CHM1_1576,160,501 - 76,222,138 (-)NCBI
T2T-CHM13v2.0577,913,542 - 77,974,918 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005248551   ⟹   XP_005248608
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,430,933 - 77,492,316 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005248552   ⟹   XP_005248609
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,436,283 - 77,492,316 (-)NCBI
GRCh37576,727,622 - 76,788,332 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011543505   ⟹   XP_011541807
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,430,933 - 77,620,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011543507   ⟹   XP_011541809
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,436,283 - 77,492,316 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017009606   ⟹   XP_016865095
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,430,933 - 77,491,997 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047417349   ⟹   XP_047273305
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,430,933 - 77,620,577 (-)NCBI
RefSeq Acc Id: XM_047417350   ⟹   XP_047273306
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,430,933 - 77,620,577 (-)NCBI
RefSeq Acc Id: XM_047417351   ⟹   XP_047273307
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,436,283 - 77,492,316 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_060738   ⟸   NM_018268
- UniProtKB: Q9NV62 (UniProtKB/Swiss-Prot),   Q9HAD4 (UniProtKB/Swiss-Prot),   A0A0S2Z5E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005248608   ⟸   XM_005248551
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005248609   ⟸   XM_005248552
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_011541807   ⟸   XM_011543505
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011541809   ⟸   XM_011543507
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_016865095   ⟸   XM_017009606
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSP00000421166   ⟸   ENST00000503035
RefSeq Acc Id: ENSP00000426141   ⟸   ENST00000504895
RefSeq Acc Id: ENSP00000425249   ⟸   ENST00000505129
RefSeq Acc Id: ENSP00000425813   ⟸   ENST00000506474
RefSeq Acc Id: ENSP00000424327   ⟸   ENST00000506307
RefSeq Acc Id: ENSP00000296679   ⟸   ENST00000296679
RefSeq Acc Id: ENSP00000424287   ⟸   ENST00000507029
RefSeq Acc Id: ENSP00000427291   ⟸   ENST00000507654
RefSeq Acc Id: ENSP00000427652   ⟸   ENST00000509701
RefSeq Acc Id: ENSP00000422922   ⟸   ENST00000509971
RefSeq Acc Id: ENSP00000427219   ⟸   ENST00000509892
RefSeq Acc Id: ENSP00000423540   ⟸   ENST00000511791
RefSeq Acc Id: ENSP00000425563   ⟸   ENST00000511630
RefSeq Acc Id: ENSP00000422510   ⟸   ENST00000511036
RefSeq Acc Id: ENSP00000423462   ⟸   ENST00000513417
RefSeq Acc Id: ENSP00000426937   ⟸   ENST00000514559
RefSeq Acc Id: ENSP00000426499   ⟸   ENST00000515253
RefSeq Acc Id: XP_047273306   ⟸   XM_047417350
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047273305   ⟸   XM_047417349
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047273307   ⟸   XM_047417351
- Peptide Label: isoform X5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9HAD4-F1-model_v2 AlphaFold Q9HAD4 1-459 view protein structure

Promoters
RGD ID:6803702
Promoter ID:HG_KWN:50519
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000220014
Position:
Human AssemblyChrPosition (strand)Source
Build 36576,823,651 - 76,824,151 (-)MPROMDB
RGD ID:6869952
Promoter ID:EPDNEW_H8141
Type:initiation region
Name:WDR41_2
Description:WD repeat domain 41
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H8142  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,492,224 - 77,492,284EPDNEW
RGD ID:6869954
Promoter ID:EPDNEW_H8142
Type:initiation region
Name:WDR41_1
Description:WD repeat domain 41
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H8141  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38577,492,507 - 77,492,567EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:25601 AgrOrtholog
COSMIC WDR41 COSMIC
Ensembl Genes ENSG00000164253 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000296679 ENTREZGENE
  ENSP00000296679.4 UniProtKB/Swiss-Prot
  ENSP00000421166.1 UniProtKB/TrEMBL
  ENSP00000422510.1 UniProtKB/TrEMBL
  ENSP00000422922.1 UniProtKB/TrEMBL
  ENSP00000423462.1 UniProtKB/TrEMBL
  ENSP00000423540.1 UniProtKB/TrEMBL
  ENSP00000424287.1 UniProtKB/Swiss-Prot
  ENSP00000424327.1 UniProtKB/TrEMBL
  ENSP00000425249.1 UniProtKB/TrEMBL
  ENSP00000425563.2 UniProtKB/TrEMBL
  ENSP00000425813.1 UniProtKB/TrEMBL
  ENSP00000426141.1 UniProtKB/TrEMBL
  ENSP00000426499 ENTREZGENE
  ENSP00000426499.1 UniProtKB/TrEMBL
  ENSP00000426937.1 UniProtKB/TrEMBL
  ENSP00000427219.1 UniProtKB/TrEMBL
  ENSP00000427291.1 UniProtKB/TrEMBL
  ENSP00000427652.1 UniProtKB/TrEMBL
Ensembl Transcript ENST00000296679 ENTREZGENE
  ENST00000296679.9 UniProtKB/Swiss-Prot
  ENST00000503035.5 UniProtKB/TrEMBL
  ENST00000504895.5 UniProtKB/TrEMBL
  ENST00000505129.5 UniProtKB/TrEMBL
  ENST00000506307.5 UniProtKB/TrEMBL
  ENST00000506474.5 UniProtKB/TrEMBL
  ENST00000507029.5 UniProtKB/Swiss-Prot
  ENST00000507654.5 UniProtKB/TrEMBL
  ENST00000509701.5 UniProtKB/TrEMBL
  ENST00000509892.5 UniProtKB/TrEMBL
  ENST00000509971.5 UniProtKB/TrEMBL
  ENST00000511036.5 UniProtKB/TrEMBL
  ENST00000511630.6 UniProtKB/TrEMBL
  ENST00000511791.1 UniProtKB/TrEMBL
  ENST00000513417.5 UniProtKB/TrEMBL
  ENST00000514559.5 UniProtKB/TrEMBL
  ENST00000515253 ENTREZGENE
  ENST00000515253.5 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000164253 GTEx
HGNC ID HGNC:25601 ENTREZGENE
Human Proteome Map WDR41 Human Proteome Map
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WDR41 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:55255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 55255 ENTREZGENE
OMIM 617502 OMIM
PANTHER PTHR22805 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134906058 PharmGKB
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024RAK0_HUMAN UniProtKB/TrEMBL
  A0A0S2Z5D8_HUMAN UniProtKB/TrEMBL
  A0A0S2Z5E0 ENTREZGENE, UniProtKB/TrEMBL
  B4DHS8_HUMAN UniProtKB/TrEMBL
  B4DK73_HUMAN UniProtKB/TrEMBL
  D6R9E7_HUMAN UniProtKB/TrEMBL
  D6R9M1_HUMAN UniProtKB/TrEMBL
  D6RA22_HUMAN UniProtKB/TrEMBL
  D6RB94_HUMAN UniProtKB/TrEMBL
  D6RBY6_HUMAN UniProtKB/TrEMBL
  D6RE66_HUMAN UniProtKB/TrEMBL
  D6RGW4_HUMAN UniProtKB/TrEMBL
  D6RH33_HUMAN UniProtKB/TrEMBL
  D6RIX6_HUMAN UniProtKB/TrEMBL
  D6RJA5_HUMAN UniProtKB/TrEMBL
  H0Y9Z3_HUMAN UniProtKB/TrEMBL
  H0YAA3_HUMAN UniProtKB/TrEMBL
  H0YAI6_HUMAN UniProtKB/TrEMBL
  Q9HAD4 ENTREZGENE
  Q9NV62 ENTREZGENE
  WDR41_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B4DT55 UniProtKB/Swiss-Prot
  Q7Z792 UniProtKB/Swiss-Prot
  Q8IWG3 UniProtKB/Swiss-Prot
  Q8IXA9 UniProtKB/Swiss-Prot
  Q8NDA7 UniProtKB/Swiss-Prot
  Q9NV62 UniProtKB/Swiss-Prot