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Gene: NAV3 (neuron navigator 3) Homo sapiens
Symbol: NAV3
Name: neuron navigator 3
Description: This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0938; POMFIL1; pore membrane and/or filament interacting like protein 1; pore membrane and/or filament-interacting-like protein 1; steerin 3; steerin-3; STEERIN3; unc-53 homolog 3; unc53H3
Mus musculus (house mouse) : Nav3 (neuron navigator 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nav3 (neuron navigator 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nav3 (neuron navigator 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NAV3 (neuron navigator 3)
Canis lupus familiaris (dog) : NAV3 (neuron navigator 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nav3 (neuron navigator 3)
Sus scrofa (pig) : NAV3 (neuron navigator 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381277,571,856 - 78,213,010 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371278,224,685 - 78,606,790 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361276,749,200 - 77,130,921 (+)NCBINCBI36hg18NCBI36
Build 341276,727,664 - 77,108,408NCBI
Celera1277,890,812 - 78,272,363 (+)NCBI
Cytogenetic Map12q21.2NCBI
HuRef1275,278,625 - 75,660,456 (+)NCBIHuRef
CHM1_11278,191,333 - 78,573,063 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NAV3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314915
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.