Abr (active BCR-related gene) - Rat Genome Database

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Gene: Abr (active BCR-related gene) Mus musculus
Analyze
Symbol: Abr
Name: active BCR-related gene
RGD ID: 1314809
MGI Page MGI
Description: Enables GTPase activator activity. Involved in several processes, including negative regulation of blood vessel remodeling; negative regulation of cellular extravasation; and regulation of vascular permeability. Acts upstream of or within several processes, including negative regulation of macrophage migration; regulation of vesicle-mediated transport; and response to lipopolysaccharide. Located in cytosol and plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including gut; mesothelium; metanephros; nervous system; and sensory organ. Orthologous to human ABR (ABR activator of RhoGEF and GTPase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 6330400K15Rik; active breakpoint cluster region-related protein; AU042359
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,307,560 - 76,468,515 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1176,307,560 - 76,514,384 (-)EnsemblGRCm39 Ensembl
GRCm381176,416,732 - 76,623,324 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,416,734 - 76,623,558 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,230,236 - 76,391,229 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,232,929 - 76,393,922 (-)NCBIMGSCv36mm8
Celera1183,928,368 - 84,081,980 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
amosite asbestos  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (ISO)
cadmium dichloride  (ISO)
choline  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (EXP)
fenvalerate  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
ozone  (ISO)
PCB138  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
piperonyl butoxide  (EXP)
potassium chromate  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
tungsten  (EXP)
urethane  (ISO)
valproic acid  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
2. Abnormal function of astroglia lacking Abr and Bcr RacGAPs. Kaartinen V, etal., Development 2001 Nov;128(21):4217-27.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11921339   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15033168   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:16602821   PMID:17116687   PMID:18799693   PMID:19703997   PMID:20962234   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23152932   PMID:23416452  
PMID:24058174   PMID:24960694   PMID:27507650   PMID:28671696   PMID:32203420   PMID:32325033   PMID:34321999   PMID:37507586  


Genomics

Comparative Map Data
Abr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391176,307,560 - 76,468,515 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1176,307,560 - 76,514,384 (-)EnsemblGRCm39 Ensembl
GRCm381176,416,732 - 76,623,324 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,416,734 - 76,623,558 (-)EnsemblGRCm38mm10GRCm38
MGSCv371176,230,236 - 76,391,229 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,232,929 - 76,393,922 (-)NCBIMGSCv36mm8
Celera1183,928,368 - 84,081,980 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
ABR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38171,003,519 - 1,229,722 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl171,003,519 - 1,229,738 (-)EnsemblGRCh38hg38GRCh38
GRCh3717906,759 - 1,133,016 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3617853,509 - 1,029,881 (-)NCBINCBI36Build 36hg18NCBI36
Build 3417853,509 - 1,029,881NCBI
Celera17918,106 - 1,102,463 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef17813,353 - 993,409 (-)NCBIHuRef
CHM1_117914,146 - 1,097,251 (-)NCBICHM1_1
T2T-CHM13v2.017890,209 - 1,120,740 (-)NCBIT2T-CHM13v2.0
Abr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81061,760,743 - 61,959,526 (-)NCBIGRCr8
mRatBN7.21061,262,516 - 61,461,331 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1061,262,516 - 61,461,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1065,908,046 - 66,051,300 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01065,413,502 - 65,556,758 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01060,883,717 - 61,026,573 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01064,565,121 - 64,657,079 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1064,567,268 - 64,657,089 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01063,250,866 - 63,449,251 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41067,617,776 - 67,760,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11067,631,103 - 67,774,585 (+)NCBI
Celera1060,277,504 - 60,420,210 (-)NCBICelera
Cytogenetic Map10q24NCBI
Abr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554812,503,315 - 2,654,244 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554812,503,309 - 2,710,667 (-)NCBIChiLan1.0ChiLan1.0
ABR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,556,006 - 8,755,510 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11710,527,138 - 10,731,505 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v017972,009 - 1,174,953 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.117893,413 - 1,116,064 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl17895,013 - 1,069,973 (-)Ensemblpanpan1.1panPan2
ABR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1944,634,117 - 44,821,454 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl944,681,411 - 44,819,249 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha943,785,466 - 43,972,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0945,451,750 - 45,638,302 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl945,451,864 - 45,638,282 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1944,278,129 - 44,417,777 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0944,517,664 - 44,703,775 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0944,604,307 - 44,790,569 (+)NCBIUU_Cfam_GSD_1.0
Abr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560243,750,170 - 43,941,125 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365386,674,907 - 6,816,674 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365386,674,595 - 6,819,511 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1246,709,880 - 46,895,808 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11246,709,840 - 46,895,819 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21248,950,856 - 49,028,680 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116732,556 - 947,329 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl16735,211 - 847,690 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605921,070,415 - 21,348,246 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247863,174,989 - 3,319,804 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247863,121,282 - 3,319,804 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Abr
5146 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:8274
Count of miRNA genes:916
Interacting mature miRNAs:1281
Transcripts:ENSMUST00000065028, ENSMUST00000072740, ENSMUST00000094012, ENSMUST00000108407, ENSMUST00000108408, ENSMUST00000130364, ENSMUST00000131059, ENSMUST00000137261, ENSMUST00000141442, ENSMUST00000151526, ENSMUST00000155035, ENSMUST00000176024, ENSMUST00000176179
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse

Markers in Region
D11Mit322  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,579,323 - 76,579,434UniSTSGRCm38
MGSCv371176,392,825 - 76,392,936UniSTSGRCm37
Celera1184,083,605 - 84,083,716UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.0UniSTS
Whitehead Genetic1140.4UniSTS
Whitehead/MRC_RH11962.33UniSTS
Whitehead_YAC11 UniSTS
AU042359  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,416,938 - 76,417,052UniSTSGRCm38
MGSCv371176,230,440 - 76,230,554UniSTSGRCm37
Celera1183,928,572 - 83,928,686UniSTS
Cytogenetic Map11B5UniSTS
cM Map1145.0UniSTS
Whitehead/MRC_RH11960.32UniSTS
D11Jcs13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,420,769 - 76,420,938UniSTSGRCm38
MGSCv371176,234,271 - 76,234,440UniSTSGRCm37
Celera1183,932,405 - 83,932,574UniSTS
Cytogenetic Map11B5UniSTS
cM Map1144.0UniSTS
UniSTS:236642  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,416,877 - 76,417,088UniSTSGRCm38
MGSCv371176,230,379 - 76,230,590UniSTSGRCm37
Celera1183,928,511 - 83,928,722UniSTS
Cytogenetic Map11B5UniSTS
cM Map1145.0UniSTS
UniSTS:236645  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,459,438 - 76,459,759UniSTSGRCm38
MGSCv371176,272,940 - 76,273,261UniSTSGRCm37
Celera1183,971,311 - 83,971,632UniSTS
Cytogenetic Map11B5UniSTS
cM Map1145.0UniSTS
AI853502  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,434,949 - 76,435,029UniSTSGRCm38
MGSCv371176,248,451 - 76,248,531UniSTSGRCm37
Celera1183,946,619 - 83,946,699UniSTS
Cytogenetic Map11B5UniSTS
cM Map1145.0UniSTS
Whitehead/MRC_RH11960.22UniSTS
Abr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381176,416,778 - 76,416,943UniSTSGRCm38
MGSCv371176,230,280 - 76,230,445UniSTSGRCm37
Celera1183,928,412 - 83,928,577UniSTS
Cytogenetic Map11B5UniSTS
cM Map1145.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001291186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001346670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001363379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK044797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL591143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL663050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY126026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY629085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB246381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF535448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF536236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ147649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LS482294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000065028   ⟹   ENSMUSP00000068982
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,307,577 - 76,359,291 (-)Ensembl
GRCm38.p6 Ensembl1176,416,751 - 76,468,465 (-)Ensembl
Ensembl Acc Id: ENSMUST00000072740   ⟹   ENSMUSP00000072522
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,307,560 - 76,462,361 (-)Ensembl
GRCm38.p6 Ensembl1176,416,734 - 76,571,535 (-)Ensembl
Ensembl Acc Id: ENSMUST00000094012   ⟹   ENSMUSP00000091551
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,307,560 - 76,400,245 (-)Ensembl
GRCm38.p6 Ensembl1176,416,734 - 76,509,419 (-)Ensembl
Ensembl Acc Id: ENSMUST00000108407   ⟹   ENSMUSP00000104044
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,307,561 - 76,399,821 (-)Ensembl
GRCm38.p6 Ensembl1176,416,735 - 76,508,995 (-)Ensembl
Ensembl Acc Id: ENSMUST00000108408   ⟹   ENSMUSP00000104045
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,309,930 - 76,386,282 (-)Ensembl
GRCm38.p6 Ensembl1176,419,104 - 76,495,456 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130364   ⟹   ENSMUSP00000135174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,345,370 - 76,359,124 (-)Ensembl
GRCm38.p6 Ensembl1176,454,544 - 76,468,298 (-)Ensembl
Ensembl Acc Id: ENSMUST00000131059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,313,874 - 76,328,046 (-)Ensembl
GRCm38.p6 Ensembl1176,423,048 - 76,437,220 (-)Ensembl
Ensembl Acc Id: ENSMUST00000137261
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,376,569 - 76,385,810 (-)Ensembl
GRCm38.p6 Ensembl1176,485,743 - 76,494,984 (-)Ensembl
Ensembl Acc Id: ENSMUST00000141442
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,349,300 - 76,385,831 (-)Ensembl
GRCm38.p6 Ensembl1176,458,474 - 76,495,005 (-)Ensembl
Ensembl Acc Id: ENSMUST00000151526   ⟹   ENSMUSP00000135544
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,355,064 - 76,384,755 (-)Ensembl
GRCm38.p6 Ensembl1176,464,238 - 76,493,929 (-)Ensembl
Ensembl Acc Id: ENSMUST00000176024   ⟹   ENSMUSP00000135691
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,369,939 - 76,504,221 (-)Ensembl
GRCm38.p6 Ensembl1176,479,113 - 76,613,395 (-)Ensembl
Ensembl Acc Id: ENSMUST00000176179   ⟹   ENSMUSP00000135515
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,369,829 - 76,468,553 (-)Ensembl
GRCm38.p6 Ensembl1176,479,003 - 76,577,727 (-)Ensembl
Ensembl Acc Id: ENSMUST00000238684   ⟹   ENSMUSP00000158745
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1176,307,560 - 76,514,384 (-)Ensembl
GRCm38.p6 Ensembl1176,416,734 - 76,623,558 (-)Ensembl
RefSeq Acc Id: NM_001291186   ⟹   NP_001278115
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,307,560 - 76,359,289 (-)NCBI
GRCm381176,416,732 - 76,468,465 (-)NCBI
Celera1183,928,366 - 84,081,992 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001346670   ⟹   NP_001333599
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,307,560 - 76,385,490 (-)NCBI
GRCm381176,416,792 - 76,494,495 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001363379   ⟹   NP_001350308
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,307,560 - 76,328,049 (-)NCBI
GRCm381176,416,732 - 76,437,305 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198018   ⟹   NP_932135
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,307,560 - 76,400,172 (-)NCBI
GRCm381176,416,732 - 76,509,419 (-)NCBI
MGSCv371176,230,236 - 76,391,229 (-)RGD
Celera1183,928,366 - 84,081,992 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_198894   ⟹   NP_942597
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,307,560 - 76,468,515 (-)NCBI
GRCm381176,416,732 - 76,577,739 (-)NCBI
MGSCv371176,230,236 - 76,391,229 (-)RGD
Celera1183,928,366 - 84,081,992 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_198895   ⟹   NP_942598
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,307,560 - 76,462,209 (-)NCBI
GRCm381176,416,732 - 76,571,384 (-)NCBI
MGSCv371176,230,236 - 76,391,229 (-)RGD
Celera1183,928,366 - 84,081,992 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030245469   ⟹   XP_030101329
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,307,560 - 76,462,471 (-)NCBI
GRCm381176,416,734 - 76,571,645 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156228   ⟹   XP_036012121
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391176,328,178 - 76,462,576 (-)NCBI
Sequence:
RefSeq Acc Id: NP_942597   ⟸   NM_198894
- Peptide Label: isoform 2
- UniProtKB: E9PUE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_942598   ⟸   NM_198895
- Peptide Label: isoform 3
- UniProtKB: Q6PDH3 (UniProtKB/Swiss-Prot),   Q6PCY1 (UniProtKB/Swiss-Prot),   Q5SYJ9 (UniProtKB/Swiss-Prot),   Q5SYJ8 (UniProtKB/Swiss-Prot),   Q5SYJ7 (UniProtKB/Swiss-Prot),   Q5SYJ5 (UniProtKB/Swiss-Prot),   Q5SSL4 (UniProtKB/Swiss-Prot),   Q3UY38 (UniProtKB/Swiss-Prot),   Q3UQJ6 (UniProtKB/Swiss-Prot),   Q3U5G0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_932135   ⟸   NM_198018
- Peptide Label: isoform 1
- UniProtKB: A0A2X0U2A7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278115   ⟸   NM_001291186
- Peptide Label: isoform 4
- UniProtKB: Q5SSL4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001350308   ⟸   NM_001363379
- Peptide Label: isoform 6
RefSeq Acc Id: XP_030101329   ⟸   XM_030245469
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001333599   ⟸   NM_001346670
- Peptide Label: isoform 5
- UniProtKB: Q5SSL4 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000135174   ⟸   ENSMUST00000130364
Ensembl Acc Id: ENSMUSP00000068982   ⟸   ENSMUST00000065028
Ensembl Acc Id: ENSMUSP00000104044   ⟸   ENSMUST00000108407
Ensembl Acc Id: ENSMUSP00000104045   ⟸   ENSMUST00000108408
Ensembl Acc Id: ENSMUSP00000135544   ⟸   ENSMUST00000151526
Ensembl Acc Id: ENSMUSP00000072522   ⟸   ENSMUST00000072740
Ensembl Acc Id: ENSMUSP00000158745   ⟸   ENSMUST00000238684
Ensembl Acc Id: ENSMUSP00000091551   ⟸   ENSMUST00000094012
Ensembl Acc Id: ENSMUSP00000135691   ⟸   ENSMUST00000176024
Ensembl Acc Id: ENSMUSP00000135515   ⟸   ENSMUST00000176179
RefSeq Acc Id: XP_036012121   ⟸   XM_036156228
- Peptide Label: isoform X2
Protein Domains
C2   DH   PH   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5SSL4-F1-model_v2 AlphaFold Q5SSL4 1-859 view protein structure

Promoters
RGD ID:6820242
Promoter ID:MM_KWN:8562
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000039558,   OTTMUST00000014079
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361176,250,436 - 76,250,936 (-)MPROMDB
RGD ID:6820247
Promoter ID:MM_KWN:8563
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000014077,   UC007KFR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361176,281,511 - 76,282,011 (-)MPROMDB
RGD ID:6820246
Promoter ID:MM_KWN:8564
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000040910,   ENSMUST00000119983,   OTTMUST00000014074,   OTTMUST00000014075,   UC007KFV.1,   UC007KFW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361176,307,651 - 76,308,972 (-)MPROMDB
RGD ID:6820244
Promoter ID:MM_KWN:8565
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain
Transcripts:NM_198018
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361176,322,446 - 76,323,227 (-)MPROMDB
RGD ID:6820245
Promoter ID:MM_KWN:8567
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain
Transcripts:OTTMUST00000014071
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361176,384,786 - 76,385,587 (-)MPROMDB
RGD ID:8675600
Promoter ID:EPDNEW_M15831
Type:initiation region
Name:Abr_2
Description:Mus musculus active BCR-related gene , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15832  EPDNEW_M15833  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381176,468,425 - 76,468,485EPDNEW
RGD ID:8675602
Promoter ID:EPDNEW_M15832
Type:initiation region
Name:Abr_3
Description:Mus musculus active BCR-related gene , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15831  EPDNEW_M15833  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381176,509,346 - 76,509,406EPDNEW
RGD ID:8675604
Promoter ID:EPDNEW_M15833
Type:initiation region
Name:Abr_1
Description:Mus musculus active BCR-related gene , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15831  EPDNEW_M15832  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381176,571,383 - 76,571,443EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107771 AgrOrtholog
Ensembl Genes ENSMUSG00000017631 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000065028 ENTREZGENE
  ENSMUST00000065028.14 UniProtKB/Swiss-Prot
  ENSMUST00000072740 ENTREZGENE
  ENSMUST00000072740.13 UniProtKB/Swiss-Prot
  ENSMUST00000094012 ENTREZGENE
  ENSMUST00000094012.11 UniProtKB/Swiss-Prot
  ENSMUST00000108407.10 UniProtKB/TrEMBL
  ENSMUST00000108408 ENTREZGENE
  ENSMUST00000108408.9 UniProtKB/Swiss-Prot
  ENSMUST00000130364.3 UniProtKB/TrEMBL
  ENSMUST00000151526.3 UniProtKB/TrEMBL
  ENSMUST00000176024.2 UniProtKB/TrEMBL
  ENSMUST00000176179.8 UniProtKB/TrEMBL
  ENSMUST00000238684.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.280.30 UniProtKB/TrEMBL
InterPro Abr/Bcr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ABR_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcr-Abl_oncoprot_oligo UniProtKB/TrEMBL
  Bcr-Abl_oncoprot_oligo_sf UniProtKB/TrEMBL
  C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DBL_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GDS_CDC24_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:109934 UniProtKB/Swiss-Prot
MGD MGI:107771 ENTREZGENE
NCBI Gene Abr ENTREZGENE
PANTHER ACTIVE BREAKPOINT CLUSTER REGION-RELATED PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23182 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Bcr-Abl_Oligo UniProtKB/TrEMBL
  PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_19 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Abr PhenoGen
PROSITE DH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48065 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF69036 UniProtKB/TrEMBL
UniProt A0A2X0U2A7 ENTREZGENE, UniProtKB/TrEMBL
  A0A571BG95_MOUSE UniProtKB/TrEMBL
  ABR_MOUSE UniProtKB/Swiss-Prot
  E9PUE7 ENTREZGENE, UniProtKB/TrEMBL
  H3BJY3_MOUSE UniProtKB/TrEMBL
  H3BKT3_MOUSE UniProtKB/TrEMBL
  H3BKV6_MOUSE UniProtKB/TrEMBL
  H3BL84_MOUSE UniProtKB/TrEMBL
  Q3U5G0 ENTREZGENE
  Q3UQJ6 ENTREZGENE
  Q3UY38 ENTREZGENE
  Q5SSL4 ENTREZGENE
  Q5SYJ5 ENTREZGENE
  Q5SYJ7 ENTREZGENE
  Q5SYJ8 ENTREZGENE
  Q5SYJ9 ENTREZGENE
  Q6PCY1 ENTREZGENE
  Q6PDH3 ENTREZGENE
UniProt Secondary Q3U5G0 UniProtKB/Swiss-Prot
  Q3UQJ6 UniProtKB/Swiss-Prot
  Q3UY38 UniProtKB/Swiss-Prot
  Q5SYJ5 UniProtKB/Swiss-Prot
  Q5SYJ7 UniProtKB/Swiss-Prot
  Q5SYJ8 UniProtKB/Swiss-Prot
  Q5SYJ9 UniProtKB/Swiss-Prot
  Q6PCY1 UniProtKB/Swiss-Prot
  Q6PDH3 UniProtKB/Swiss-Prot