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Gene: Spic (Spi-C transcription factor (Spi-1/PU.1 related)) Mus musculus
Symbol: Spic
Name: Spi-C transcription factor (Spi-1/PU.1 related)
RGD ID: 1314797
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in blastocyst development and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system; liver; and nervous system. Orthologous to human SPIC (Spi-C transcription factor); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU019198; C76795; P; Prf; pu.1-related factor; Sp; Spi-C; transcription factor Spi-C
Homo sapiens (human) : SPIC (Spi-C transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spic (Spi-C transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spic (Spi-C transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SPIC (Spi-C transcription factor)
Canis lupus familiaris (dog) : SPIC (Spi-C transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spic (Spi-C transcription factor)
Sus scrofa (pig) : SPIC (Spi-C transcription factor)
Chlorocebus sabaeus (African green monkey) : SPIC (Spi-C transcription factor)
Heterocephalus glaber (naked mole-rat) : Spic (Spi-C transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391088,511,131 - 88,518,885 (-)NCBI
GRCm381088,675,269 - 88,683,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1088,674,772 - 88,685,015 (-)EnsemblGRCm38mm10GRCm38
MGSCv371088,138,014 - 88,145,768 (-)NCBIGRCm37mm9NCBIm37
MGSCv361088,105,076 - 88,112,821 (-)NCBImm8
Celera1090,655,323 - 90,663,281 (-)NCBICelera
Cytogenetic Map10C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Spic
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314797
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.