Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Rexo4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of REXO4 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Rexo4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of REXO4 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Rexo4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of REXO4 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of REXO4 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,4-dinitrotoluene | affects expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of REXO4 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of REXO4 mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of REXO4 mRNA | CTD | PMID:30071829 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Rexo4 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of REXO4 mRNA | CTD | PMID:18648102 | acrolein | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of REXO4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of REXO4 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | ISO | Rexo4 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of REXO4 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of REXO4 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of REXO4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of REXO4 mRNA | CTD | PMID:32699268 | aristolochic acid A | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of REXO4 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Rexo4 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of REXO4 mRNA | CTD | PMID:23650126 | bisphenol A | increases expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of REXO4 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Rexo4 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of REXO4 mRNA | CTD | PMID:35598803 | bisphenol A | decreases expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of REXO4 mRNA | CTD | PMID:30816183 and PMID:34947998 | bisphenol A | affects methylation | ISO | Rexo4 (Mus musculus) | 6480464 | bisphenol A affects the methylation of REXO4 promoter | CTD | PMID:27334623 | butan-1-ol | multiple interactions | EXP | | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of REXO4 mRNA | CTD | PMID:29432896 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of REXO4 mRNA | CTD | PMID:35301059 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of REXO4 mRNA | CTD | PMID:26472689 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of REXO4 mRNA | CTD | PMID:35301059 | caffeine | decreases phosphorylation | EXP | | 6480464 | Caffeine results in decreased phosphorylation of REXO4 protein | CTD | PMID:35688186 | chrysene | increases expression | ISO | Rexo4 (Mus musculus) | 6480464 | chrysene results in increased expression of REXO4 mRNA | CTD | PMID:26377693 | cisplatin | multiple interactions | EXP | | 6480464 | [Piroxicam co-treated with Cisplatin] results in decreased expression of REXO4 mRNA | CTD | PMID:21858171 | coumarin | decreases phosphorylation | EXP | | 6480464 | coumarin results in decreased phosphorylation of REXO4 protein | CTD | PMID:35688186 | cytarabine | decreases expression | EXP | | 6480464 | Cytarabine results in decreased expression of REXO4 mRNA | CTD | PMID:21198554 | enzyme inhibitor | multiple interactions | EXP | | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of REXO4 protein | CTD | PMID:23301498 | fonofos | increases methylation | EXP | | 6480464 | Fonofos results in increased methylation of REXO4 promoter | CTD | PMID:22847954 | FR900359 | affects phosphorylation | EXP | | 6480464 | FR900359 affects the phosphorylation of REXO4 protein | CTD | PMID:37730182 | oxaliplatin | multiple interactions | ISO | Rexo4 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of REXO4 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | EXP | | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of REXO4 mRNA more ... | CTD | PMID:32699268 | parathion | increases methylation | EXP | | 6480464 | Parathion results in increased methylation of REXO4 promoter | CTD | PMID:22847954 | perfluorononanoic acid | increases expression | EXP | | 6480464 | perfluoro-n-nonanoic acid results in increased expression of REXO4 mRNA | CTD | PMID:32588087 | pirinixic acid | decreases expression | ISO | Rexo4 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of REXO4 mRNA | CTD | PMID:18445702 | piroxicam | multiple interactions | EXP | | 6480464 | [Piroxicam co-treated with Cisplatin] results in decreased expression of REXO4 mRNA | CTD | PMID:21858171 | rotenone | decreases expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of REXO4 mRNA | CTD | PMID:19013527 | rotenone | increases expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of REXO4 mRNA | CTD | PMID:28374803 | senecionine | decreases expression | ISO | Rexo4 (Mus musculus) | 6480464 | senecionine results in decreased expression of REXO4 protein | CTD | PMID:35357534 | Soman | decreases expression | ISO | Rexo4 (Rattus norvegicus) | 6480464 | Soman results in decreased expression of REXO4 mRNA | CTD | PMID:19281266 | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of REXO4 mRNA | CTD | PMID:31533062 | terbufos | increases methylation | EXP | | 6480464 | terbufos results in increased methylation of REXO4 promoter | CTD | PMID:22847954 | tetrachloromethane | increases expression | ISO | Rexo4 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of REXO4 mRNA | CTD | PMID:27339419 and PMID:31919559 | topotecan | multiple interactions | ISO | Rexo4 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of REXO4 mRNA | CTD | PMID:25729387 | triptonide | increases expression | ISO | Rexo4 (Mus musculus) | 6480464 | triptonide results in increased expression of REXO4 mRNA | CTD | PMID:33045310 | |