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Gene: DCLRE1A (DNA cross-link repair 1A) Homo sapiens
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Symbol: DCLRE1A
Name: DNA cross-link repair 1A
Description: Exhibits 5'-3' exodeoxyribonuclease activity. Predicted to be involved in double-strand break repair via nonhomologous end joining; interstrand cross-link repair; and protection from non-homologous end joining at telomere. Localizes to the fibrillar center and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae); DNA cross-link repair 1A protein; DNA-crosslink repair gene SNM1; hSNM1A; KIAA0086; PSO2; PSO2 homolog; SNM1; SNM1 homolog A; SNM1A
Orthologs:
Mus musculus (house mouse) : Dclre1a (DNA cross-link repair 1A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dclre1a (DNA cross-link repair 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dclre1a (DNA cross-link repair 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : DCLRE1A (DNA cross-link repair 1A)
Canis lupus familiaris (dog) : DCLRE1A (DNA cross-link repair 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dclre1a (DNA cross-link repair 1A)
Sus scrofa (pig) : DCLRE1A (DNA cross-link repair 1A)
Chlorocebus sabaeus (African green monkey) : DCLRE1A (DNA cross-link repair 1A)
Heterocephalus glaber (naked mole-rat) : Dclre1a (DNA cross-link repair 1A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl10113,834,725 - 113,854,383 (-)Ensembl
GRCh3810113,834,725 - 113,854,394 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710115,594,483 - 115,614,163 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610115,584,474 - 115,603,597 (-)NCBINCBI36hg18NCBI36
Build 3410115,584,473 - 115,603,597NCBI
Celera10109,321,854 - 109,341,216 (-)NCBI
Cytogenetic Map10q25.3NCBI
HuRef10109,221,884 - 109,241,549 (-)NCBIHuRef
CHM1_110115,876,518 - 115,896,196 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DCLRE1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314610
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.