Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Estradiol results in increased expression of MIDEAS mRNA | CTD | PMID:23019147 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mideas (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MIDEAS mRNA | CTD | PMID:22298810 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mideas (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ELMSAN1 mRNA | CTD | PMID:33387578 | 3-methylcholanthrene | multiple interactions | ISO | MIDEAS (Homo sapiens) | 6480464 | Methylcholanthrene promotes the reaction [AHR protein binds to MIDEAS promoter] | CTD | PMID:20348232 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of ELMSAN1 gene | CTD | PMID:31683443 | antirheumatic drug | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of MIDEAS mRNA | CTD | PMID:24449571 | benzo[a]pyrene | affects methylation | ISO | MIDEAS (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MIDEAS 3' UTR and Benzo(a)pyrene affects the methylation of MIDEAS 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of MIDEAS mRNA | CTD | PMID:27858113 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | benzo[b]fluoranthene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of MIDEAS mRNA | CTD | PMID:27858113 | bisphenol A | affects expression | ISO | Mideas (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of MIDEAS mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Mideas (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ELMSAN1 mRNA and bisphenol A results in decreased expression of MIDEAS mRNA | CTD | PMID:32145629 and PMID:34947998 | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of MIDEAS mRNA | CTD | PMID:29038090 | cadmium dichloride | increases expression | ISO | Mideas (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased expression of ELMSAN1 mRNA | CTD | PMID:33453195 | caffeine | affects phosphorylation | ISO | MIDEAS (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of MIDEAS protein | CTD | PMID:35688186 | chrysene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of MIDEAS mRNA | CTD | PMID:27858113 | chrysene | decreases expression | EXP | | 6480464 | chrysene results in decreased expression of MIDEAS mRNA | CTD | PMID:26377693 | cisplatin | multiple interactions | ISO | MIDEAS (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of MIDEAS mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of MIDEAS mRNA | CTD | PMID:27392435 | coumarin | decreases phosphorylation | ISO | MIDEAS (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of MIDEAS protein | CTD | PMID:35688186 | crotonaldehyde | decreases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | 2-butenal results in decreased expression of MIDEAS mRNA | CTD | PMID:20471460 | diazinon | increases methylation | ISO | MIDEAS (Homo sapiens) | 6480464 | Diazinon results in increased methylation of MIDEAS gene | CTD | PMID:22964155 | dicrotophos | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | dicrotophos results in increased expression of MIDEAS mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | MIDEAS (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MIDEAS mRNA | CTD | PMID:29803840 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of MIDEAS mRNA | CTD | PMID:35436446 | ethylparaben | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of MIDEAS mRNA | CTD | PMID:37690743 | fipronil | increases expression | ISO | Mideas (Rattus norvegicus) | 6480464 | fipronil results in increased expression of MIDEAS mRNA | CTD | PMID:34044035 | fluoranthene | multiple interactions | EXP | | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of MIDEAS mRNA | CTD | PMID:28329830 | formaldehyde | decreases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of MIDEAS mRNA | CTD | PMID:20655997 | FR900359 | affects phosphorylation | ISO | MIDEAS (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of MIDEAS protein | CTD | PMID:37730182 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ELMSAN1 mRNA | CTD | PMID:36331819 | lead(0) | affects expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Lead affects the expression of MIDEAS mRNA | CTD | PMID:28903495 | leflunomide | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Leflunomide results in increased expression of MIDEAS mRNA | CTD | PMID:28988120 | methylmercury chloride | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of MIDEAS mRNA | CTD | PMID:28001369 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of MIDEAS mRNA | CTD | PMID:34911549 | paracetamol | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MIDEAS mRNA | CTD | PMID:29067470 | paracetamol | increases expression | ISO | Mideas (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of ELMSAN1 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ELMSAN1 mRNA | CTD | PMID:36331819 | phenylmercury acetate | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of MIDEAS mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | MIDEAS (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MIDEAS mRNA | CTD | PMID:27188386 | potassium dichromate | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of MIDEAS protein | CTD | PMID:23718831 | SB 431542 | multiple interactions | ISO | MIDEAS (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Silver results in increased expression of MIDEAS mRNA | CTD | PMID:26014281 | silver(0) | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Silver results in increased expression of MIDEAS mRNA | CTD | PMID:26014281 | tetraphene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of MIDEAS mRNA | CTD | PMID:27858113 | tetraphene | decreases expression | EXP | | 6480464 | benz(a)anthracene results in decreased expression of MIDEAS mRNA | CTD | PMID:26377693 | thioacetamide | increases expression | ISO | Mideas (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of MIDEAS mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of MIDEAS mRNA | CTD | PMID:23557971 | trichostatin A | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | trichostatin A results in increased expression of MIDEAS mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | MIDEAS (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MIDEAS mRNA | CTD | PMID:27188386 | valproic acid | increases methylation | ISO | MIDEAS (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of MIDEAS gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MIDEAS mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | MIDEAS (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MIDEAS mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | MIDEAS (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MIDEAS mRNA | CTD | PMID:28001369 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Phenotype Annotations
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Mammalian Phenotype
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 2. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:12466851 | PMID:12520002 | PMID:12904583 | PMID:14610273 | PMID:16141072 | PMID:16141073 | PMID:17967808 |
| PMID:18799693 | PMID:20362541 | PMID:21122108 | PMID:21267068 | PMID:21677750 | PMID:21873635 | PMID:22922362 | PMID:23892456 | PMID:32591534 |
Genomics
Comparative Map Data
| Mideas (Mus musculus - house mouse) |
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| MIDEAS (Homo sapiens - human) |
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| Mideas (Rattus norvegicus - Norway rat) |
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| Mideas (Chinchilla lanigera - long-tailed chinchilla) |
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| MIDEAS (Pan paniscus - bonobo/pygmy chimpanzee) |
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| MIDEAS (Canis lupus familiaris - dog) |
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| Mideas (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| MIDEAS (Sus scrofa - pig) |
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| MIDEAS (Chlorocebus sabaeus - green monkey) |
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| Mideas (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Mideas
2230 total Variants 
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