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Gene: PTTG1IP (PTTG1 interacting protein) Homo sapiens
Symbol: PTTG1IP
Name: PTTG1 interacting protein
RGD ID: 1314337
Description: Exhibits p53 binding activity. Involved in negative regulation of signal transduction by p53 class mediator; positive regulation of cellular protein metabolic process; and protein import into nucleus. Localizes to cytoplasm and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C21orf1; C21orf3; PBF; pituitary tumor-transforming gene 1 protein-interacting protein; pituitary tumor-transforming gene protein-binding factor; PTTG-binding factor
Mus musculus (house mouse) : Pttg1ip (pituitary tumor-transforming 1 interacting protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pttg1ip (PTTG1 interacting protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pttg1ip (PTTG1 interacting protein)
Pan paniscus (bonobo/pygmy chimpanzee) : PTTG1IP (PTTG1 interacting protein)
Canis lupus familiaris (dog) : PTTG1IP (PTTG1 interacting protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pttg1ip (PTTG1 interacting protein)
Sus scrofa (pig) : PTTG1IP (PTTG1 interacting protein)
Chlorocebus sabaeus (African green monkey) : PTTG1IP (PTTG1 interacting protein)
Heterocephalus glaber (naked mole-rat) : Pttg1ip (PTTG1 interacting protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2144,849,585 - 44,873,903 (-)EnsemblGRCh38hg38GRCh38
GRCh382144,849,598 - 44,873,690 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372146,269,500 - 46,294,487 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362145,093,941 - 45,118,169 (-)NCBINCBI36hg18NCBI36
Build 342145,093,940 - 45,118,169NCBI
Celera2131,376,467 - 31,400,666 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2131,643,011 - 31,667,259 (-)NCBIHuRef
CHM1_12145,830,425 - 45,854,730 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PTTG1IP
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314337
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.